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The Bovine Pericardium Matrix in Immediate Implant-Based Breast Reconstruction

  • Original Article
  • Breast Surgery
  • Published:
Aesthetic Plastic Surgery Aims and scope Submit manuscript

Abstract

Background

Acellular dermal matrices have been introduced to optimize direct-to-implant breast reconstruction. We selected a bovine pericardium noncross-linked matrix.

Methods

The study consists in the retrospective analysis of 123 patients (141 breasts) who underwent conservative mastectomy and immediate implant-based breast reconstruction with bovine pericardium matrix Veritas® from March 2012 to October 2017.

Results

The overall rates of early and late complications, after a median follow-up of 51.84 months, were, respectively, 37.6% and 24.1%. The most noticeable early complications were flap ischemia [n = 39 (27.7%)], hematoma [n = 5 (3.6%)], marginal skin flap necrosis [n = 5 (3.6%)] and dehiscence of the surgical wound [n = 2 (1.4%)]. The most common late complications were rippling [n = 18 (12.7%)] and seroma [n = 4 (2.8%)]. The rate of clinically relevant capsular contracture was low: 12.1% (n = 17) presented grade II and only 2.1%% (n = 3) grade III. Implant substitution became necessary for five patients (3.6%). Early complications occurred more frequently in patients undergoing therapeutic mastectomy (p = 0.031). Patients undergoing preoperative radiotherapy more frequently developed late complications (p = 0.012). A clinically relevant capsular contracture (grade II–III) was found in higher average patients age (p = 0.0019). The left side developed less frequently late complications except for rippling (p = 0.002). Rippling occurred more frequently in patients who sustained a nipple skin-sparing mastectomy (p = 0.035).

Conclusion

Our results further support the safety of Veritas® in immediate implant-based breast reconstruction.

Level of Evidence IV

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

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Authors and Affiliations

  1. Breast Surgery Unit, AZIENDA USL-IRCCS Reggio Emilia, Viale Risorgimento no. 80, 42123, Reggio Emilia, Italy

    Fabio Castagnetti, Chiara Bertani, Monica Foroni, Giuseppe Falco, Eugenio Cenini, Filomena De Bonis & Guglielmo Ferrari

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  1. Fabio Castagnetti
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  2. Chiara Bertani
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  3. Monica Foroni
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  4. Giuseppe Falco
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  5. Eugenio Cenini
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  6. Filomena De Bonis
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  7. Guglielmo Ferrari
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Correspondence to Fabio Castagnetti.

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Castagnetti, F., Bertani, C., Foroni, M. et al. The Bovine Pericardium Matrix in Immediate Implant-Based Breast Reconstruction. Aesth Plast Surg 44, 2051–2060 (2020). https://doi.org/10.1007/s00266-020-01651-z

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  • DOI: https://doi.org/10.1007/s00266-020-01651-z

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