Skip to main content

Advertisement

Log in

Pre-operative predictors of lower extremity swelling following total knee arthroplasty in patients with venous insufficiency and osteoarthritis

  • Original Paper
  • Published:
International Orthopaedics Aims and scope Submit manuscript

Abstract

Purpose

Post-operative swelling and oedema following total knee arthroplasty (TKA) are one of the most important causes of dissatisfaction. We aimed to assess the clinical variables associated with post-operative swelling and edema after TKA and to compare their performance in respect of predicting them pre-operatively.

Methods

The study cohort comprised 116 patients who underwent TKA between January 2018 and May 2019 in our centre. The diameters and the grade of venous insufficiency (VI) in the lower extremity veins were measured with duplex ultrasonography preoperatively and at one and three months post-operatively. The study cohort was divided into the patients with leg swelling positive with a difference in leg circumference of > 2 cm (n = 56, 48.2%) and leg swelling negative with a difference of ≤ 2 cm (n = 60, 51.7%) from the pre-operative leg diameter.

Results

Independent predictors for lower extremity swelling were pre-operative great saphenous diameter (GSV) diameter > 5.5 mm [odds ratio (OR) 2.51, 95% CI 0.24–0.91; p = 0.0012], GSV reflux > 1 s [OR 3.28, 95% CI 1.16–12.1; p = 0.003], deep only VI [OR 1.32, 95% CI 0.74–1.87; p = 0.021], CEAP C4–6 [OR 1.62, 95% CI 0.36–0.91; p = 0.018], and hypothyroidism [OR 1.55, 95% CI 1.31–11.2; p = 0.031].

Conclusion

GSV diameter of > 5.38 mm and GSV reflux duration > 1.23 s had the best predictive value for lower extremity oedema following TKA.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  1. Carr AJ, Robertsson O, Graves S, Price AJ, Arden NK, Judge A, Beard DJ (2012) Knee replacement. Lancet 379(9823):1331–1340. https://doi.org/10.1016/S0140-6736(11)60752-6

    Article  Google Scholar 

  2. Loyd BJ, Stackhouse S, Dayton M, Hogan C, Bade M, Stevens-Lapsley J (2019) The relationship between lower extremity swelling, quadriceps strength, and functional performance following total knee arthroplasty. Knee 26(2):382–391. https://doi.org/10.1016/j.knee.2019.01.012

    Article  PubMed  PubMed Central  Google Scholar 

  3. Mizner RL, Petterson SC, Snyder-Mackler L (2005) Quadriceps strength and the time course of functional recovery after total knee arthroplasty. J Orthop Sports Phys Ther 35(7):424–436. https://doi.org/10.2519/jospt.2005.35.7.424

    Article  PubMed  Google Scholar 

  4. Mizner RL, Petterson SC, Stevens JE, Axe MJ, Snyder-Mackler L (2005) Preoperative quadriceps strength predicts functional ability one year after total knee arthroplasty. J Rheumatol 32(8):1533–1539

    PubMed  Google Scholar 

  5. Petterson SC, Mizner RL, Stevens JE, Raisis LEO, Bodenstab A, Newcomb W, Snyder-Mackler L (2009) Improved function from progressive strengthening interventions after total knee arthroplasty: a randomized clinical trial with an imbedded prospective cohort. Arthritis Care Res 61(2):174–183. https://doi.org/10.1002/art.24167

    Article  Google Scholar 

  6. Thacoor A, Sandiford NA (2019) Cryotherapy following total knee arthroplasty: what is the evidence? J Orthop Surg (Hong Kong) 27(1):2309499019832752. https://doi.org/10.1177/2309499019832752

    Article  CAS  Google Scholar 

  7. Cheung A, Lykostratis H, Holloway I (2014) Compression bandaging improves mobility following total knee replacement in an enhanced recovery setting. J Perioper Pract 24(4):84–86. https://doi.org/10.1177/175045891602400405

    Article  CAS  PubMed  Google Scholar 

  8. Liu P, Mu X, Zhang Q, Liu Z, Wang W, Guo W (2020) Should compression bandage be performed after total knee arthroplasty? A meta-analysis of randomized controlled trials. J Orthop Surg Res 15(1):52. https://doi.org/10.1186/s13018-019-1527-9

    Article  PubMed  PubMed Central  Google Scholar 

  9. Navarro TP, Delis KT, Ribeiro AP (2002) Clinical and hemodynamic significance of the greater saphenous vein diameter in chronic venous insufficiency. Arch Surg 137(11):1233–1237. https://doi.org/10.1001/archsurg.137.11.1233

    Article  PubMed  Google Scholar 

  10. Youn YJ, Lee J (2019) Chronic venous insufficiency and varicose veins of the lower extremities. Korean J Intern Med 34(2):269–283. https://doi.org/10.3904/kjim.2018.230

    Article  PubMed  Google Scholar 

  11. Charalambides C, Beer M, Melhuish J, Williams RJ, Cobb AG (2005) Bandaging technique after knee replacement. Acta Orthop 76(1):89–94. https://doi.org/10.1080/00016470510030382

    Article  PubMed  Google Scholar 

  12. Munk S, Jensen NJ, Andersen I, Kehlet H, Hansen TB (2013) Effect of compression therapy on knee swelling and pain after total knee arthroplasty. Knee Surg Sports Traumatol Arthrosc 21(2):388–392. https://doi.org/10.1007/s00167-012-1963-0

    Article  PubMed  Google Scholar 

  13. Pinsornsak P, Chumchuen S (2013) Can a modified Robert Jones bandage after knee arthroplasty reduce blood loss? A prospective randomized controlled trial. Clin Orthop Relat Res 471(5):1677–1681. https://doi.org/10.1007/s11999-013-2786-0

    Article  PubMed  PubMed Central  Google Scholar 

  14. Matthews CN, Chen AF, Daryoush T, Rothman RH, Maltenfort MG, Hozack WJ (2019) Does an elastic compression bandage provide any benefit after primary TKA? Clin Orthop Relat Res 477(1):134–144. https://doi.org/10.1097/CORR.0000000000000459

    Article  PubMed  Google Scholar 

  15. Gunaratne R, Pratt DN, Banda J, Fick DP, Khan RJK, Robertson BW (2017) Patient dissatisfaction following total knee arthroplasty: a systematic review of the literature. J Arthroplast 32(12):3854–3860. https://doi.org/10.1016/j.arth.2017.07.021

    Article  Google Scholar 

  16. Nakano N, Shoman H, Olavarria F, Matsumoto T, Kuroda R, Khanduja V (2020) Why are patients dissatisfied following a total knee replacement? A systematic review. Int Orthop:1–46. https://doi.org/10.1007/s00264-020-04607-9

  17. Healy WL, Seidman J, Pfeifer BA, Brown DG (1994) Cold compressive dressing after total knee arthroplasty. Clin Orthop Relat Res 299:143–146

    Google Scholar 

  18. Smith J, Stevens J, Taylor M, Tibbey J (2002) A randomized, controlled trial comparing compression bandaging and cold therapy in postoperative total knee replacement surgery. Orthop Nurs 21(2):61–66. https://doi.org/10.1097/00006416-200203000-00009

    Article  PubMed  Google Scholar 

  19. Levy AS, Marmar E (1993) The role of cold compression dressings in the postoperative treatment of total knee arthroplasty. Clin Orthop Relat Res 297:174–178

    Google Scholar 

  20. Matsen FA 3rd, Krugmire RB Jr (1974) The effect of externally applied pressure on post-fracture swelling. J Bone Joint Surg Am 56(8):1586–1591

    Article  Google Scholar 

  21. Ogata K, Whiteside LA (1982) Effects of external compression on blood flow to muscle and skin. Clin Orthop Relat Res 168:105–107

    Google Scholar 

  22. Zhang W, Li N, Chen S, Tan Y, Al-Aidaros M, Chen L (2014) The effects of a tourniquet used in total knee arthroplasty: a meta-analysis. J Orthop Surg Res 9(1):13. https://doi.org/10.1186/1749-799X-9-13

    Article  PubMed  PubMed Central  Google Scholar 

  23. Cai DF, Fan QH, Zhong HH, Peng S, Song H (2019) The effects of tourniquet use on blood loss in primary total knee arthroplasty for patients with osteoarthritis: a meta-analysis. J Orthop Surg Res 14(1):348. https://doi.org/10.1186/s13018-019-1422-4

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  24. Clarke MT, Longstaff L, Edwards D, Rushton N (2001) Tourniquet-induced wound hypoxia after total knee replacement. J Bone Joint Surg (Br) 83(1):40–44. https://doi.org/10.1302/0301-620x.83b1.10795

    Article  CAS  Google Scholar 

Download references

Funding

This project was internally funded.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Gokhan Cansabuncu.

Ethics declarations

Conflict of interest

The authors declare that they have no conflicts of interest.

Additional information

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Level of evidence: Case–Control study, Level III

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Cansabuncu, G., Gumus, F. Pre-operative predictors of lower extremity swelling following total knee arthroplasty in patients with venous insufficiency and osteoarthritis. International Orthopaedics (SICOT) 45, 2561–2567 (2021). https://doi.org/10.1007/s00264-020-04888-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00264-020-04888-0

Keywords

Navigation