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Meta-analysis shows that obesity may be a significant risk factor for prosthetic joint infections

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Abstract

Purpose

Our aim was to evaluate the association between the different degree of obesity and prosthetic joint infections (PJIs) after total hip replacement (THR) by performing a meta-analysis.

Methods

PubMed, Cochrane library and Embase databases up to May, 2014 were retrieved for identifying relevant studies. Relative risk (RR) and their 95 % confidence intervals (CIs) were used as effect sizes.

Results

A total of 15 articles were included in this meta-analysis. The overall analyses showed that the risk of PJIs in the BMI ≥ 30 group and in BMI ≥ 40 group were significantly higher than that in the BMI < 30 group. As well, the prospective pooled results showed that overweight and obesity could significantly increase the incidence of PJIs.

Conclusions

Our meta-analysis indicates that all of obesity levels can significantly increase the risk of PJIs. However, further studies with more strict design are need in the future.

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Competing interests

The authors declare that they have no competing interests.

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Authors and Affiliations

  1. Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No.1095 Jiefang Road, Wuhan, 430030, Hubei Province, China

    Zhongxi Ma, Fengjin Guo, Jun Qi, Wei Xiang & Jinming Zhang

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  1. Zhongxi Ma
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  2. Fengjin Guo
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  3. Jun Qi
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  4. Wei Xiang
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  5. Jinming Zhang
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Correspondence to Fengjin Guo.

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Ma, Z., Guo, F., Qi, J. et al. Meta-analysis shows that obesity may be a significant risk factor for prosthetic joint infections. International Orthopaedics (SICOT) 40, 659–667 (2016). https://doi.org/10.1007/s00264-015-2914-4

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  • DOI: https://doi.org/10.1007/s00264-015-2914-4

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