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Extracorporeally irradiated autografts in pelvic reconstruction after malignant tumour resection

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Abstract.

We treated 15 patients suffering from an extracompartmental malignant pelvic tumour by resecting the affected part of the bone, irradiating it extracorporeally with 300 Gy, and reimplanting it after having removed the bulk of the lesion. Adjuvant therapies were used according to the type and extension of the tumour. Follow-up was an average of 4 years 6 months. Complications were seen in 13 patients. Most mechanical complications were related to the use of hip arthroplasties. Internal fixation of the graft failed in one case only, infection was seen in three cases, and seven patients died after local recurrence. Functional scores were fair. Although many complications were seen, this method remains our treatment of choice.

Résumé.

Nous avons traité 15 malades qui souffraient d'une tumeur pelvienne maligne extracompartimentale par résection de la partie affectée, 'irradiation extracorporelle de 300 Gy, puis réimplantation après avoir enlevé la charge de la lésion. Les thérapies adjuvantes ont été utilisées d'après le type et l'extension de la tumeur. Le suivi moyen était de quatre ans et demi. Treize malades ont eu des complications. La plupart des complications mécaniques étaient relatives à la prothése de la hanche. La fixation de la greffe a failli seulement une fois. Il y a eu trois infections. Sept malades sont morts après une récidive locale. Les scores fonctionnels sont moyens. Bien que beaucoup de complications puissent survenir, cette méthode reste notre traitement de choix.

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Sys, G., Uyttendaele, D., Poffyn, B. et al. Extracorporeally irradiated autografts in pelvic reconstruction after malignant tumour resection. International Orthopaedics (SICOT) 26, 174–178 (2002). https://doi.org/10.1007/s00264-002-0352-6

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  • DOI: https://doi.org/10.1007/s00264-002-0352-6

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