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Mapping of hepatic vasculature in potential living liver donors: comparison of gadoxetic acid-enhanced MR imaging using CAIPIRINHA technique with CT angiography

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Abstract

Purpose

To retrospectively evaluate gadoxetic acid-enhanced magnetic resonance angiography (MRA) using controlled aliasing in parallel imaging results in higher acceleration (CAIPIRINHA) technique for mapping hepatic vascular anatomy in potential living liver donors, with CT angiography (CTA) as reference standard.

Methods

82 potential living liver donors who underwent MRA and CTA were enrolled in this HIPAA-compliant IRB-approved study. MRA and CTA images were evaluated by two reviewers in consensus with respect to (1) image quality scores for depiction of the hepatic vessels and (2) accuracy of MRA for determining the hepatic vascular variants with CTA as reference standard. The image quality scores were compared using Fisher’s exact test between MRA and CTA.

Results

The accuracy for determining the hepatic arterial, portal, and hepatic venous variants and segment IV arterial origin was 73, 90, 79, and 55%, respectively, compared to CTA. However, subjective image quality for depiction of hepatic arteries in MRA was significantly lower than CTA (p < 0.001). The portal and hepatic venous image quality was almost equal in both modalities (p = 0.059) except left hepatic vein being depicted better on CT images (p = 0.023).

Conclusion

Gadoxetic acid-enhanced MRA using CAIPIRINHA technique is feasible for mapping hepatic vasculature in potential living liver donors, with moderate accuracy for arterial variants and good to excellent results for hepatic and portal vein variants, compared with CTA. However, the specific delineation of segment IV arterial origin was possible in just over half of the liver donors with MRA.

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Authors and Affiliations

  1. Joint Department of Medical Imaging, Mount Sinai Hospital & Women’s College Hospital, University Health Network, University of Toronto, 610 University Ave, 3-957, Toronto, ON M5G, Canada

    Kartik Jhaveri, Lijun Guo, Luís Guimarães & Ravi Menezes

  2. Department of Surgery, University Health Network, University of Toronto, 610 University Ave, 3-957, Toronto, ON M5G, Canada

    Ian McGilvray, Mark Cattral & David Grant

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  1. Kartik Jhaveri
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  2. Lijun Guo
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Correspondence to Kartik Jhaveri.

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Jhaveri, K., Guo, L., Guimarães, L. et al. Mapping of hepatic vasculature in potential living liver donors: comparison of gadoxetic acid-enhanced MR imaging using CAIPIRINHA technique with CT angiography. Abdom Radiol 43, 1682–1692 (2018). https://doi.org/10.1007/s00261-017-1379-x

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  • DOI: https://doi.org/10.1007/s00261-017-1379-x

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