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Epidermoid cyst in intrapancreatic accessory spleen: computed tomography findings and clinical manifestation

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Abstract

Objective

This study aims to assess retrospectively the imaging features of computed tomography (CT) and clinical characteristics of epidermoid cyst in intrapancreatic accessory spleen (ECIPAS).

Methods

Seven consecutive patients with pathologically confirmed ECIPAS were included. CT images and clinical data were analyzed. The CT features emphasized included the location, size, calcification, cystic features, surrounding accessory spleen, density, and enhancement of the lesions.

Results

Five patients were male and two were female with a mean age of 43.2 years ranging from 25 to 66 years. Most cases were incidentally detected. All lesions were situated in the pancreatic tail, wherein the mean size was 4.4 cm. The cyst appeared unilocular in four cases and multilocular in three cases. An accessory spleen surrounding the cyst was recognized in all seven cases, and the cystic wall of ECIPAS showed a contrast enhancement similar to that of the spleen during multiphasic scans.

Conclusion

ECIPAS is an extremely rare entity. The diagnosis of an ECIPAS should be considered when enhancing the cystic wall of the lesion in the pancreatic tail similar to that of the spleen during multiphasic scans.

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References

  1. Davidson ED, Campbell WG, Hersh T (1980) Epidermoid splenic cyst occurring in an intrapancreatic accessory spleen. Dig Dis Sci 25(12):964–967

    Article  CAS  PubMed  Google Scholar 

  2. Hwang HS, Lee SS, Kim SC, Seo DW, Kim J (2011) Intrapancreatic accessory spleen: clinicopathologic analysis of 12 cases. Pancreas 40(6):956–965

    Article  PubMed  Google Scholar 

  3. Higaki K, Jimi A, Watanabe J, Kusaba A, Kojiro M (1998) Epidermoid cyst of the spleen with CA19-9 or carcinoembryonic antigen productions: report of three cases. Am J Surg Pathol 22(6):704–708

    Article  CAS  PubMed  Google Scholar 

  4. Morohoshi T, Hamamoto T, Kunimura T, et al. (1991) Epidermoid cyst derived from an accessory spleen in the pancreas. A case report with literature survey. Acta Pathol Jpn 41(12):916–921

    CAS  PubMed  Google Scholar 

  5. Tang X, Tanaka Y, Tsutsumi Y (1994) Epithelial inclusion cysts in an intrapancreatic accessory spleen. Pathol Int 44(8):652–654

    Article  CAS  PubMed  Google Scholar 

  6. Tateyama H, Tada T, Murase T, Fujitake S, Eimoto T (1998) Lymphoepithelial cyst and epidermoid cyst of the accessory spleen in the pancreas. Mod Pathol 11(12):1171–1177

    CAS  PubMed  Google Scholar 

  7. Sasou S, Nakamura S, Inomata M (1999) Epithelial splenic cysts in an intrapancreatic accessory spleen and spleen. Pathol Int 49(12):1078–1083

    Article  CAS  PubMed  Google Scholar 

  8. Horibe Y, Murakami M, Yamao K, et al. (2001) Epithelial inclusion cyst (epidermoid cyst) formation with epithelioid cell granuloma in an intrapancreatic accessory spleen. Pathol Int 51(1):50–54

    Article  CAS  PubMed  Google Scholar 

  9. Kadota K, Kushida Y, Miyai Y, et al. (2010) Epidermoid cyst in an intrapancreatic accessory spleen: three case reports and review of the literatures. Pathol Oncol Res 16(3):435–442

    Article  PubMed  Google Scholar 

  10. Furukawa H, Kosuge T, Kanai Y, Mukai K (1998) Epidermoid cyst in an intrapancreatic accessory spleen: CT and pathologic findings. AJR Am J Roentgenol 171(1):271

    Article  CAS  PubMed  Google Scholar 

  11. Fink AM, Kulkarni S, Crowley P, Crameri JA (2002) Epidermoid cyst in a pancreatic accessory spleen mimicking an infected abdominal cyst in a child. AJR Am J Roentgenol 179(1):206–208

    Article  CAS  PubMed  Google Scholar 

  12. Sonomura T, Kataoka S, Chikugo T, et al. (2002) Epidermoid cyst originating from an intrapancreatic accessory spleen. Abdom Imaging 27(5):560–562

    Article  CAS  PubMed  Google Scholar 

  13. Yokomizo H, Hifumi M, Yamane T, et al. (2002) Epidermoid cyst of an accessory spleen at the pancreatic tail: diagnostic value of MRI. Abdom Imaging 27(5):557–559

    Article  CAS  PubMed  Google Scholar 

  14. Motosugi U, Yamaguchi H, Ichikawa T, et al. (2010) Epidermoid cyst in intrapancreatic accessory spleen: radiological findings including superparamagnetic iron oxide-enhanced magnetic resonance imaging. J Comput Assist Tomogr 34(2):217–222

    Article  PubMed  Google Scholar 

  15. Nakae Y, Hayakawa T, Kondo T, et al. (1991) Epidermoid cyst occurring in a pancreatic accessory spleen. J Clin Gastroenterol 13(3):362–364

    Article  CAS  PubMed  Google Scholar 

  16. Choi SK, Ahn SI, Hong KC, et al. (2000) A case of epidermoid cyst of the intrapancreatic accessory spleen. J Korean Med Sci 15(5):589–592

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. Tsutsumi S, Kojima T, Fukai Y, et al. (2000) Epidermoid cyst of an intrapancreatic accessory spleen: a case report. Hepatogastroenterology 47(35):1462–1464

    CAS  PubMed  Google Scholar 

  18. Kanazawa H, Kamiya J, Nagino M, et al. (2004) Epidermoid cyst in an intrapancreatic accessory spleen: a case report. J Hepatobiliary Pancreat Surg 11(1):61–63

    Article  PubMed  Google Scholar 

  19. Ru K, Kalra A, Ucci A (2007) Epidermoid cyst of intrapancreatic accessory spleen. Dig Dis Sci 52(5):1229–1232

    Article  PubMed  Google Scholar 

  20. Gleeson FC, Kendrick ML, Chari ST, Zhang L, Lew MJ (2008) Epidermoid accessory splenic cyst masquerading as a pancreatic mucinous cystic neoplasm. Endoscopy 40(Suppl 2):E141–E142

    Article  PubMed  Google Scholar 

  21. Itano O, Shiraga N, Kouta E, et al. (2008) Epidermoid cyst originating from an intrapancreatic accessory spleen. J Hepatobiliary Pancreat Surg 15(4):436–439

    Article  PubMed  Google Scholar 

  22. Servais EL, Sarkaria IS, Solomon GJ, Gumpeni P, Lieberman MD (2008) Giant epidermoid cyst within an intrapancreatic accessory spleen mimicking a cystic neoplasm of the pancreas: case report and review of the literature. Pancreas 36(1):98–100

    Article  PubMed  Google Scholar 

  23. Reiss G, Sickel JZ, See-Tho K, Ramrakhiani S (2009) Intrapancreatic splenic cyst mimicking pancreatic cystic neoplasm diagnosed by EUS-FNA. Gastrointest Endosc 70(3):557–558

    Article  PubMed  Google Scholar 

  24. Zhang Z, Wang JC (2009) An epithelial splenic cyst in an intrapancreatic accessory spleen. A case report JOP 10(6):664–666

    PubMed  Google Scholar 

  25. Itano O, Chiba N, Wada T, et al. (2010) Laparoscopic resection of an epidermoid cyst originating from an intrapancreatic accessory spleen: report of a case. Surg Today 40(1):72–75

    Article  PubMed  Google Scholar 

  26. Khashab MA, Canto ML, Singh VK, et al. (2011) Endosonographic and elastographic features of a rare epidermoid cyst of an intrapancreatic accessory spleen. Endoscopy 43(Suppl 2):E193–E194

    Article  PubMed  Google Scholar 

  27. Ough YD, Nash HR, Wood DA (1981) Mesothelial cysts of the spleen with squamous metaplasia. Am J Clin Pathol 76(5):666–669

    Article  CAS  PubMed  Google Scholar 

  28. Bürrig KF (1988) Epithelial (true) splenic cysts. Pathogenesis of the mesothelial and so-called epidermoid cyst of the spleen. Am J Surg Pathol 12(4):275–281

    Article  PubMed  Google Scholar 

  29. Lifschitz-Mercer B, Open M, Kushnir I, Czernobilsky B (1994) Epidermoid cyst of the spleen: a cytokeratin profile with comparison to other squamous epithelia. Virchows Arch 424(2):213–216

    Article  CAS  PubMed  Google Scholar 

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Acknowledgments

This study was supported in part by a grant-in-aid for scientific research from the Science and Technology Commission of Shanghai Municipality (Project No. 10JC1410900) and National Natural Science Foundation of China (Project No. 81071281).

Conflict of interest

All authors have no conflict of interest.

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Authors and Affiliations

  1. Department of Radiology, Ruijin Hospital, Shanghai Jiao tong University, School of Medicine, No. 197, Ruijin Er Road, Shanghai, 200025, China

    Shudong Hu, Linxiao zhu, Qi song & Kemin Chen

Authors
  1. Shudong Hu
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  2. Linxiao zhu
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  3. Qi song
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  4. Kemin Chen
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Corresponding author

Correspondence to Kemin Chen.

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Hu, S., zhu, L., song, Q. et al. Epidermoid cyst in intrapancreatic accessory spleen: computed tomography findings and clinical manifestation. Abdom Radiol 37, 828–833 (2012). https://doi.org/10.1007/s00261-012-9851-0

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  • DOI: https://doi.org/10.1007/s00261-012-9851-0

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