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Imaging biomarkers: from research to patient care—a shift in view

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References

  1. Biomarkers Definitions Working Group. Biomarkers and surrogate endpoints: preferred definitions and conceptual framework. Clin Pharmacol Ther 2001;69(3):89–95 (Mar).

    Article  Google Scholar 

  2. Richter WS. Imaging biomarkers as surrogate endpoints for drug development. Eur J Nucl Med Mol Imaging 2006;33 Suppl 1:6–10 (Jul).

    Article  PubMed  Google Scholar 

  3. Pien HH, Fischman AJ, Thrall JH, Sorensen AG. Using imaging biomarkers to accelerate drug development and clinical trials. Drug Discov Today 2005;10(4):259–66 (Feb 15).

    Article  PubMed  CAS  Google Scholar 

  4. Web site of the Center for Biomarkers in Imaging http://www.biomarkers.org/.

  5. Stephen RM, Gillies RJ. Promise and progress for functional and molecular imaging of response to targeted therapies. Pharm Res 2007;24(6):1172–85 (Epub 2007 Mar 24 Jun).

    Article  PubMed  CAS  Google Scholar 

  6. Massoud TF, Gambhir SS. Integrating noninvasive molecular imaging into molecular medicine: an evolving paradigm. Trends Mol Med 2007 May;13(5):183–91 (Epub 2007 Apr 2).

    Article  PubMed  CAS  Google Scholar 

  7. Dickerson BC, Sperling RA. Neuroimaging biomarkers for clinical trials of disease-modifying therapies in Alzheimer’s disease. NeuroRx 2005;2(2):348–60 (Apr).

    Article  PubMed  Google Scholar 

  8. Chertkow H, Black S. Imaging biomarkers and their role in dementia clinical trials. Can J Neurol Sci 2007;34 Suppl 1:S77–83 (Mar).

    PubMed  Google Scholar 

  9. Schuster DP. The opportunities and challenges of developing imaging biomarkers to study lung function and disease. Am J Respir Crit Care Med 2007;176(3):224–30 (Epub 2007 May 3 Aug 1).

    Article  PubMed  Google Scholar 

  10. Blasberg RG. Imaging update: new windows, new views. Clin Cancer Res 2007;13(12):3444–8 (Jun 15).

    Article  PubMed  Google Scholar 

  11. Wester HJ. Nuclear imaging probes: from bench to bedside. Clin Cancer Res. 2007 Jun 15;13(12):3470–81.

    Article  PubMed  CAS  Google Scholar 

  12. Rudin M. Imaging readouts as biomarkers or surrogate parameters for the assessment of therapeutic interventions Eur Radiol. 2007 Mar 6; [Epub ahead of print].

  13. Temple RJ. A regulatory authority’s opinion about surrogate endpoints. In:Nimmo WS, Tucker GT, editors. Clinical measurement in drug evaluation. New York: Wiley; 1995. pp. 1–2.

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Authors and Affiliations

  1. Institute of Radiological Sciences, University of Milan, Unit of Nuclear Medicine, Hospital San Paolo, Via Antonio di Rudinì, 8, 20142, Milan, Italy

    Giovanni Lucignani

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  1. Giovanni Lucignani
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Correspondence to Giovanni Lucignani.

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The commentaries in this section derive from a literature search and include summaries of recently published articles compiled and linked to each other by extensive use of the text contained in the articles examined.

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Lucignani, G. Imaging biomarkers: from research to patient care—a shift in view. Eur J Nucl Med Mol Imaging 34, 1693–1697 (2007). https://doi.org/10.1007/s00259-007-0569-0

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