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The histological variants of liposarcoma: predictive MRI findings with prognostic implications, management, follow-up, and differential diagnosis

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Abstract

Liposarcoma is the single most common soft tissue sarcoma accounting for up to 35 % of sarcomas. It represents a histologically diverse group of soft tissue tumors that demonstrate a wide range of imaging appearances with varied behavior patterns. Correspondingly, more aggressive histological subtypes often require management that includes a combination of surgery, chemotherapy, and radiation therapy. Distinguishing among liposarcoma subtypes has important therapeutic and prognostic implications. In this manuscript, we review the liposarcoma subtypes and their histologic and MRI findings, prognostic implications, and differential diagnostic considerations.

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Authors and Affiliations

  1. Department of Radiology, Mount Sinai Medical Center, Miami Beach, FL, USA

    Magda Rizer

  2. Department of Radiology and Imaging Sciences, Section of Musculoskeletal Imaging, Emory Healthcare, Atlanta, GA, USA

    Adam D. Singer

  3. Bone and Soft Tissue Pathology, Department of Pathology, Emory Healthcare, Atlanta, GA, USA

    Mark Edgar

  4. Section of Musculoskeletal Imaging, Miller School of Medicine, University of Miami, Miami, FL, USA

    Jean Jose & Ty K. Subhawong

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  1. Magda Rizer
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  2. Adam D. Singer
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  3. Mark Edgar
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  5. Ty K. Subhawong
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Correspondence to Magda Rizer.

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Rizer, M., Singer, A.D., Edgar, M. et al. The histological variants of liposarcoma: predictive MRI findings with prognostic implications, management, follow-up, and differential diagnosis. Skeletal Radiol 45, 1193–1204 (2016). https://doi.org/10.1007/s00256-016-2409-4

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