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Radiography of successful bone marrow transplantation for osteopetrosis

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Abstract

Hematopoietic stem cell transplantation (HSCT) is the only curative therapy for autosomal recessive infantile malignant osteopetrosis, an otherwise fatal disease. HSCT has also been utilized in patients with the less severe autosomal recessive intermediate form in an attempt to correct hematologic abnormalities and halt cranial nerve deficits caused by progressive cranial foraminal stenosis. Successful engraftment is accompanied by rapid normalization of radiographic signs of osteopetrosis.

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Authors and Affiliations

  1. Division of Diagnostic Imaging, Department of Diagnostic Radiology, University of Texas M.D. Anderson Cancer Center, Houston, TX, USA

    Colleen M. Costelloe & Farzin Eftekhari

  2. Department of Pediatrics, University of Texas M.D. Anderson Cancer Center, Houston, TX, USA

    Demetrios Petropoulos

  3. Musculoskeletal Section, Division of Diagnostic Imaging, Department of Diagnostic Radiology, University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Unit #1273, Houston, TX, 77030, USA

    Colleen M. Costelloe

Authors
  1. Colleen M. Costelloe
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  2. Farzin Eftekhari
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  3. Demetrios Petropoulos
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Correspondence to Colleen M. Costelloe.

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Costelloe, C.M., Eftekhari, F. & Petropoulos, D. Radiography of successful bone marrow transplantation for osteopetrosis. Skeletal Radiol 36 (Suppl 1), 34–37 (2007). https://doi.org/10.1007/s00256-006-0141-1

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  • DOI: https://doi.org/10.1007/s00256-006-0141-1

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