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Ewing’s sarcoma of the humerus mimicking fibrous dysplasia on imaging and biological behavior

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Abstract

We present the case of a 12-year-old girl who presented with a pathological fracture through a benign-appearing osteolytic lesion that was presumed to represent fibrous dysplasia. The fracture healed, and over the next 2.5 years there was further refracturing and healing with progressive osteolysis. A biopsy was performed and revealed Ewing’s sarcoma. The disease was locally controlled by neoadjuvant chemotherapy and radiation therapy. The patient is disease free with excellent function 6 years following the discovery of the lesion. We illustrate and discuss the sequence of events.

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References

  1. Ushigome S, Machinami R, Sorensen PH. Ewing sarcoma/primitive neuroectodermal tumor (PNET). In: Fletcher CDM, Unni KK (eds) World Health Organization classification of tumors. Pathology and genetics. Tumors of soft tissue and bone. IARC 2000; pp 298–300.

  2. Siegal G, Dal Cin P, Araujo ES. Fibrous dysplasia. In: Fletcher CDM, Unni KK (eds) World Health Organization classification of tumors. Pathology and genetics. Tumors of soft tissue and bone. IARC 2000; pp 341–342.

  3. Dal Cin P, Sciot R, Brys P, et al. Recurrent chromosome aberrations in fibrous dysplasia of the bone. A report of the CHAMP study group. Cancer Genet Cytogenet 2000; 122:30–32.

    Article  PubMed  Google Scholar 

  4. Ruggieri P, Sim FH, Bond JR, Unni KK. Malignancies in fibrous dysplasia. Cancer 1994; 73:1411–1424.

    CAS  PubMed  Google Scholar 

  5. Bhagia SM, Grimer RJ, Davies AM, Mangham DC. Ewing’s sarcoma presenting as a solitary bone cyst. Skeletal Radiol 1997; 26:722–724.

    Article  CAS  PubMed  Google Scholar 

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Author notes

  1. Murali Sundaram

    Present address: Diagnostic Radiology, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA

Authors and Affiliations

  1. Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA

    Murali Sundaram

  2. Department of Surgical Pathology, Mayo Clinic, Rochester, Minnesota, USA

    Carrie Y. Inwards

  3. Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA

    Thomas E. Shives

  4. Department of Pediatric and Adolescent Medicine and Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA

    Peter M. Anderson

Authors
  1. Murali Sundaram
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  2. Carrie Y. Inwards
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  3. Thomas E. Shives
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  4. Peter M. Anderson
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Corresponding author

Correspondence to Murali Sundaram.

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Sundaram, M., Inwards, C.Y., Shives, T.E. et al. Ewing’s sarcoma of the humerus mimicking fibrous dysplasia on imaging and biological behavior. Skeletal Radiol 34, 285–289 (2005). https://doi.org/10.1007/s00256-004-0847-x

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  • DOI: https://doi.org/10.1007/s00256-004-0847-x

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