Skip to main content

Advertisement

SpringerLink
Log in

Plexiform schwannoma of the forearm

  • Case Report
  • Published:
Skeletal Radiology Aims and scope Submit manuscript

Abstract

We report a case of plexiform schwannoma located in the flexor muscles of the forearm in the absence of other signs of neurofibromatosis or schwannomatosis. Magnetic resonance examination revealed a multinodular irregular inhomogeneous mass. Some nodules displayed a peripheral, high intensity rim and a central low intensity (target sign) on T2-weighted images. Pre-operative diagnosis of the rare plexiform schwannoma may be possible with careful imaging examination for the target sign.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1A, B
Fig. 2
Fig. 3
Fig. 4A–D

Similar content being viewed by others

References

  1. Masson P. Human tumors: histology, diagnosis, and technique. 2nd edn, translated by Kobernick SD. Wayne State University Press, Detroit 1970:1103.

  2. Tomita K, Mori K, Miyajima Y, Nakashima T. Plexiform schwannoma of the neck extending deeply to the mediastinum. Acta Otolaryngol Suppl 1998; 539:106–109.

    CAS  PubMed  Google Scholar 

  3. Sheikh S, Gomes M, Montgomery E. Multiple plexiform schwannomas in a patient with neurofibromatosis. J Thorac Cardiovasc Surg 1998; 115:240–242.

    CAS  PubMed  Google Scholar 

  4. Chiodi E, Centanni F, Gattazzo D, Morini G. Plexiform schwannomatosis of the tibial nerve: study with MR and surgical findings in a case (in Italian). Radiol Med (Torino) 1998; 95:107–110.

    Google Scholar 

  5. Rongioletti F, Drago F, Robora A. Multiple cutaneous plexiform schwannomas with tumors of the central nervous system. Arch Dermatol 1989; 125:431–432.

    CAS  PubMed  Google Scholar 

  6. Shishiba T, Niimura M, Ohtsuka F, Tsuru N. Multiple cutaneous neurilemmomas as a skin manifestation of neurilemmomatosis. J Am Acad Dermatol 1984; 10:744–754.

    CAS  PubMed  Google Scholar 

  7. Enzinger FM, Weiss SW. Soft tissue tumors. Mosby, St Louis 1983:587–589.

  8. Harkin JC, Arrington JH, Reed RJ. Benign plexiform schwannoma, a lesion distinct from plexiform neurofibroma (abstract). J Neuropathol Exp Neurol 1978; 37:622.

    Google Scholar 

  9. Nodl F. Multiple reine Neurinome der Haut. Arch Klin Exp Dermatol 1958; 207: 291–301.

    CAS  PubMed  Google Scholar 

  10. Ishida T, Kuroda M, Motoi T, Oka T, Imamura T, Machinami R. Phenotypic diversity of neurofibromatosis 2: association with plexiform schwannoma. Histopathology 1998; 32:264–270.

    Article  CAS  PubMed  Google Scholar 

  11. Val-Bernal JF, Figols J, Vazquez-Barquero A. Cutaneous plexiform schwannoma associated with neurofibromatosis type 2. Cancer 1995; 76:1181–1186.

    CAS  PubMed  Google Scholar 

  12. Iwashita T, Enjoji M. Plexiform neurilemoma: a clinicopathological and immunohistochemical analysis of 23 tumours from 20 patients. Virchows Arch A 1987; 411:305–9.

    CAS  Google Scholar 

  13. Reith JD, Goldblum JR. Multiple cutaneous plexiform schwannomas. Report of a case and review of the literature with particular reference to the association with type 1 and 2 neurofibromatosis and schwannomatosis. Arch Pathol Lab Med 1996; 120:399–401.

    CAS  PubMed  Google Scholar 

  14. Purcell SM, Dixon SL. Schwannomatosis: an unusual variant of neurofibromatosis or a distinct clinical entity? Arch Dermatol 1989; 125:390–393.

    CAS  PubMed  Google Scholar 

  15. Baraosa J, Hansen LS. Solitary multilobular schwannoma of the oral cavity. J Oral Med 1984; 39:232–235.

    PubMed  Google Scholar 

  16. Cokelaere K, Sciot R, Geboes K. Esophageal Plexiform Schwanoma. Int J Surg Pathol 2000; 8:353–57.

    PubMed  Google Scholar 

  17. Escalas Taberner J, Saus C, Gonzales A, Mestre F, Martin A. Plexiform schwannoma (in French). Ann Dermatol Venereol 1997; 124:184.

    PubMed  Google Scholar 

  18. Fletcher CD, Davies SE. Benign plexiform (multinodular) schwannoma: a rare tumour unassociated with neurofibromatosis. Histopathology 1986; 10:971–980.

    CAS  PubMed  Google Scholar 

  19. Guarino M. Plexiform schwannoma. Immunohistochemistry of Schwann cell markers, intermediate filaments and extracellular matrix components. Pathol Res Pract 1993; 189:913–920.

    CAS  PubMed  Google Scholar 

  20. Heifetz SA, Sadove AM, Joyner ML, Davidson D. Intraoral plexiform (multinodular) neurilemoma. Pediatr Pathol 1991; 11:457–465.

    CAS  PubMed  Google Scholar 

  21. Hirose T, Scheithauer BW, Sano T. Giant plexiform schwannoma: a report of two cases with soft tissue and visceral involvement. Mod Pathol 1997; 10:1075–1081.

    CAS  PubMed  Google Scholar 

  22. Ikushima K, Ueda T, Kudawara I, Nakanishi K, Yoshikawa H. Plexiform schwannoma of the foot. Eur Radiol 1999; 9:1653–1655.

    CAS  PubMed  Google Scholar 

  23. Kao GF, Laskin WB, Olsen TG. Solitary cutaneous plexiform neurilemmoma (schwannoma): a clinicopathologic, immunohistochemical, and ultrastructural study of 11 cases. Mod Pathol 1989; 2:20–26.

    CAS  PubMed  Google Scholar 

  24. Kleinman GM, Sanders FJ, Gagliardi JM. Plexiform schwannoma. Clin Neuropathol 1985; 4:265–266.

    CAS  PubMed  Google Scholar 

  25. Krolls SO, McGinnis JP Jr, Quon D. Multinodular versus plexiform neurilemoma of the hard palate. Report of a case. Oral Surg Oral Med Oral Pathol 1994; 77:154–157.

    CAS  PubMed  Google Scholar 

  26. Mannara GM, La Rosa FC, Marino F. Plexiform schwannoma of the cheek. J Larygol Otol 1999; 113:1034–1035.

    CAS  Google Scholar 

  27. Megahed M. Plexiform schwannoma. Am J Surg Pathol 1994; 16:288–293.

    CAS  Google Scholar 

  28. Pinto RG, Mandreker S, Nadkarni N, Amonkar SS, Lobo D, Noronha FP. Plexiform (multinodular) schwannoma in a child—a rare variant of schwannoma. J Indian Med Assoc 1995; 93:318–317.

    CAS  PubMed  Google Scholar 

  29. Posner MA, McMahon MS, Desai P. Plexiform schwannoma (neurilemmoma) associated with macrodactyly: a case report. J Hand Surg [Am] 1996; 21:707–710.

    Google Scholar 

  30. Qureshi F, Hozakewich H, Perez-Atayde A. Plexiform schwannoma in children (abstract). Lab Invest 1986; 54:7.

    Google Scholar 

  31. Santos LD, Currie BG, Killingsworth MC. Case report: plexiform schwannoma of the vulva. Pathology 2001; 33: 526–531.

    CAS  PubMed  Google Scholar 

  32. Tanaka M, Hara M, Hosokawa M, Miyazawa T, Tagami H. Linear cutaneous neurilemmomas on the forehead. Clin Exp Dermatol 1991; 16:247–249.

    CAS  PubMed  Google Scholar 

  33. Woodruff JM, Funkhouser JW, Marshall ML, Thompson NJ, Godwin TA, Erlandson RA. Plexiform (multinodular) schwannoma. A tumor simulating the plexiform neurofibroma. Am J Surg Pathol 1983; 7:691–697.

    CAS  PubMed  Google Scholar 

  34. National Institutes of Health Consensus Development Conference. Neurofibromatosis: conference statement. Arch Neurol 1988; 45:575–578.

    PubMed  Google Scholar 

  35. Ogose A, Hotta T, Morita T, Yamamura S, Hosaka N, Kobayashi H, Hirata Y. Tumors of peripheral nerves: correlation of symptoms, clinical sign, imaging features, and histologic diagnosis. Skeletal Radiol 1999; 28:183–188.

    Article  CAS  PubMed  Google Scholar 

  36. Donner TR, Voorhies RM, Kline DG. Neural sheath tumors of major nerves. J Neurosurg 1994;81:362–373.

    CAS  PubMed  Google Scholar 

  37. Gouliamos AD, Kontogiannis DS, Androulidakis EJ, Kalovidouris AE, Vlahos LJ, Papavasiliou CG. Spinal neurilemmomas and neurofibromas: central dot signal in postgadolinum MRI. J Comput Assist Tomogr 1993; 17:446–448.

    CAS  PubMed  Google Scholar 

  38. Varma DGK, Moulopoulos A, Sara AS. MR imaging of extracranial nerve sheath tumors. J Comput Assist Tomogr 1992; 16:448–453.

    CAS  PubMed  Google Scholar 

  39. Bhargava R, Parham DM, Laster OE, Chari RS, Chen G, Fletcher BD. MR imaging differentiation of benign and malignant peripheral nerve sheath tumors: use of target sign. Pediatr Radiol 1997; 27:124–129.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Division of Orthopedic Surgery, Department of Regenerative and Transplant Medicine, Graduate School of Medical and Dental Sciences, Niigata University, Asahimachi 1-751, 951-8510, Niigata, Japan

    Keiichi Katsumi, Akira Ogose, Tetsuo Hotta, Hiroshi Hatano, Hiroyuki Kawashima & Naoto Endo

  2. Division of Pathology, Niigata University Hospital, Niigata, Japan

    Hajime Umezu

Authors
  1. Keiichi Katsumi
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Akira Ogose
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Tetsuo Hotta
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Hiroshi Hatano
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Hiroyuki Kawashima
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Hajime Umezu
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Naoto Endo
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Akira Ogose.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Katsumi, K., Ogose, A., Hotta, T. et al. Plexiform schwannoma of the forearm. Skeletal Radiol 32, 719–723 (2003). https://doi.org/10.1007/s00256-003-0701-6

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00256-003-0701-6

Keywords

Search

Navigation