Abstract
Recently, thermophilic Thermoanaerobacterium species have attracted increasing attentions in consolidated bioprocessing (CBP), which can directly utilize lignocellulosic materials for biofuels production. Compared to the mesophilic process, thermophilic process shows greater prospects in CBP due to its relatively highly efficiency of lignocellulose degradation. In addition, thermophilic conditions can avoid microbial contamination, reduce the cooling costs, and further facilitate the downstream product recovery. However, only few reviews specifically focused on the microbial applications of thermophilic Thermoanaerobacterium species in lignocellulosic biorefinery. Accordingly, this review will comprehensively summarize the recent advances of Thermoanaerobacterium species in lignocellulosic biorefinery, including their secreted xylanases and bioenergy production. Furthermore, the co-culture can significantly reduce the metabolic burden and achieve the more complex work, which will be discussed as the further perspectives.
Key points
• Thermoanaerobacterium species, promising chassis for lignocellulosic biorefinery.
• Potential capability of hemicellulose degradation for Thermoanaerobacterium species.
• Efficient bioenergy production by Thermoanaerobacterium species through metabolic engineering.
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This work was supported by the National Key R&D Program of China (2018YFA0902200), National Natural Science Foundation of China (21978130, 22008113, 22078151 and 31961133017), Jiangsu Province Natural Science Foundation for Youths (BK20200683), and China Postdoctoral Science Foundation (No. 2020 M671465).
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Jiang M and Xin F provided ideas for the article. Jiang Y and Wu M wrote the manuscript. Xin F and Zhang W revised the article. Liu Y and Mou L contributed to the conception and reviewed the manuscript. All authors read and approved the manuscript.
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Wu, M., Jiang, Y., Liu, Y. et al. Microbial application of thermophilic Thermoanaerobacterium species in lignocellulosic biorefinery. Appl Microbiol Biotechnol 105, 5739–5749 (2021). https://doi.org/10.1007/s00253-021-11450-4
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DOI: https://doi.org/10.1007/s00253-021-11450-4