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Cellulase and xylanase synergism in industrial biotechnology

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Abstract

Biocatalysts provide a major advantage to bio-based economy over chemical catalysts by catalyzing various useful transformations in an environment friendly manner along with other major benefits of selectivity, specificity, and low energy consumption. Since last decade, cellulase is the 3rd highest used enzyme in industry in various processes. Xylanase is also one amongst the widely used enzymes, and many industrial applications require synergistic action of both of these enzymes. These applications predominantly include bioethanol production, deinking of waste paper, animal feed processing, food processing, paper and pulp production, removal of fine fibers from textile material (biostoning), and pharmaceuticals. These enzymes are produced by microorganisms (fungi and bacteria), and hence, the microorganisms producing both cellulases and xylanases are in high demand by these industries. This review focuses on the synergistic applications of cellulase and xylanase enzymes across various industrial sectors. It also discusses the potential applications and the need of the microbial systems (fungi and bacteria) secreting both of these enzymes and the future prospects of their development into an integral part of various industrial processes.

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References

  • Abrão FO, Duarte ER, Pessoa MS, dos Santos VL, de Freitas Júnior LF, Barros K de O, Huges AFS, Silva TD, Rodriguez NM (2017) Notable fibrolytic enzyme production by Aspergillus spp. isolates from the gastrointestinal tract of beef cattle fed in lignified pastures. PLoS One 12:e0183628

    PubMed  PubMed Central  Google Scholar 

  • Adesogan AT (2005) Improving forage quality and animal performance with fibrolytic enzymes. In Florida ruminant nutrition symposium: 91–109

  • Adetunji C, Oloke J, Kumar A, Swaranjit S, Akpor B (2017) Synergetic effect of rhamnolipid from Pseudomonas aeruginosa C1501 and phytotoxic metabolite from Lasiodiplodia pseudotheobromae C1136 on Amaranthus hybridus L. and Echinochloa crus-galli weeds. Environ Sci Pollut Res 24:13700–13709

    CAS  Google Scholar 

  • Akpinar M, Urek R (2017) Peach and cherry agroindustrial wastes: new and economic sources for the production of lignocellulolytic enzymes. Acta Chim Slov 64:422–430

    CAS  PubMed  Google Scholar 

  • Al-Ghazzewi FH, Tester RF (2012) Efficacy of cellulase and mannanase hydrolysates of konjac glucomannan to promote the growth of lactic acid bacteria. J Sci Food Agric 92(11):2394–2396

    CAS  PubMed  Google Scholar 

  • Amerah AM, Gilbert C, Simmins PH, Ravindran V (2011) Influence of feed processing on the efficacy of exogenous enzymes in broiler diets. Worlds Poult Sci J 67(1):29–46

    Google Scholar 

  • Arnold FH (2018) Directed evolution: bringing new chemistry to life. Angew Chem Int Ed Eng 57(16):4143–4148

    CAS  Google Scholar 

  • Arriola KG, Oliveira AS, Ma ZX, Lean IJ, Giurcanu MC, Adesogan AT (2017) A meta-analysis on the effect of dietary application of exogenous fibrolytic enzymes on the performance of dairy cows. J Dairy Sci 100(6):4513–4527

    CAS  PubMed  Google Scholar 

  • Asem D, Leo VV, Passari AK, Tonsing MV, Joshi JB, Uthandi S, Hashem A, Abd Allah EF, Singh BP (2017) Evaluation of gastrointestinal bacterial population for the production of holocellulose enzymes for biomass deconstruction. PLoS One 12:e0186355

    PubMed  PubMed Central  Google Scholar 

  • Bajpai P (1999) Application of enzymes in the pulp and paper industry. Biotechnol Prog 15(2):147–157

    CAS  PubMed  Google Scholar 

  • Bajpai P (2004) Biological bleaching of chemical pulps. Crit Rev Biotechnol 24(1):1–58

    CAS  PubMed  Google Scholar 

  • Bajpai P (2010) Overview of pulp and papermaking processes. In: Environmentally friendly production of pulp and paper. Wiley, NJ, pp 8–43

    Google Scholar 

  • Bajpai P (2012) Biodeinking. In: Biotechnology for pulp and paper processing. Springer, New York: 7–13 and 139–158

  • Bala A, Singh B (2017) Concomitant production of cellulase and xylanase by thermophilic mould Sporotrichum thermophile in solid state fermentation and their applicability in bread making. World J Microbiol Biotechnol 33(6):109

    PubMed  Google Scholar 

  • Bamforth CW, Martin HL (1983) The degradation of β-glucan during malting and mashing: the role of β-glucanase. J Inst Brew 89(4):303–307

    CAS  Google Scholar 

  • Beauchemin KA, Rode LM, Sewalt VJH (1995) Fibrolytic enzymes increase fiber digestibility and growth rate of steers fed dry forages. Can J Anim Sci 75(4):641–644

    Google Scholar 

  • Beauchemin KA, Rode LM, Maekawa M, Morgavi DP, Kampen R (2000) Evaluation of a nonstarch polysaccharidase feed enzyme in dairy cow diets. J Dairy Sci 83(3):543–553

    CAS  PubMed  Google Scholar 

  • Beck CI, Scott D (1974) Enzymes in foods—for better or worse. In: Whitaker JR (ed) Food related enzymes. advances in chemistry series, pp 1–30. https://doi.org/10.1021/ba-1974-0136.ch001

    Chapter  Google Scholar 

  • Bedford MR, Partridge GG (2010) Feed enzyme, the future: bright hope or regulatory minefield. In: Bedford MR, Partridge GG (eds) Enzymes in farm animal nutrition. CAB International, Wallingford, pp 304–312

    Google Scholar 

  • Beg Q, Kapoor M, Mahajan L, Hoondal G (2001) Microbial xylanases and their industrial applications: a review. Appl Microbiol Biotechnol 56(3):326–338

    CAS  PubMed  Google Scholar 

  • Behera SS, Ray RC (2016) Solid state fermentation for production of microbial cellulases: recent advances and improvement strategies. Int J Biol Macromol 86:656–669

    CAS  PubMed  Google Scholar 

  • Berikashvili V, Sokhadze K, Kachlishvili E, Elisashvili V, Chikindas ML (2018) Bacillus amyloliquefaciens spore production under solid-state fermentation of lignocellulosic residues. Probiotics Antimicrob Proteins 10(4):755–761

    CAS  PubMed  Google Scholar 

  • Bhagia S, Ferreira JFS, Kothari N, Nunez A, Liu X, da Silva DN, Suarez DL, Kumar R, Wyman CE (2018) Sugar yield and composition of tubers from Jerusalem Artichoke (Helianthus tuberosus) irrigated with saline waters. Biotechnol Bioeng 115:1475–1484

    CAS  PubMed  Google Scholar 

  • Bhat MK (2000) Cellulases and related enzymes in biotechnology. Biotechnol Adv 18(5):355–383

    CAS  PubMed  Google Scholar 

  • Bhatia L, Sharma A, Bachheti RK, Chandel AK (2019) Lignocellulose derived functional oligosaccharides: production, properties, and health benefits. Prep Biochem Biotechnol 49(8):744–758

    CAS  PubMed  Google Scholar 

  • Bhatt SM, Bal JS (2019) Bioprocessing perspective in biorefineries. In: Srivastava N, Srivastava M, Mishra PK, Upadhyay SN, Ramteke PW, Gupta VK (eds) Sustainable approaches for biofuels production technologies: from current status to practical implementation. vol 7. Springer, pp 1–23

  • Bisaria R, Madan M, Vasudevan P (1997) Utilisation of agro-residues as animal feed through bioconversion. Bioresour Technol 59(1):5–8

    CAS  Google Scholar 

  • Blanco A, Diaz P, Martinez J, Vidal T, Torres AL, Pastor FIJ (1998) Cloning of a new endoglucanase gene from Bacillus sp. BP-23 and characterisation of the enzyme performance in paper manufacture from cereal straw. Appl Microbiol Biotechnol 50(1):48–54

    CAS  PubMed  Google Scholar 

  • Bokinsky G, Peralta-Yahya PP, George A, Holmes BM, Steen EJ, Dietrich J, Lee TS, Tullman-Ercek D, Voigt CA, Simmons BA, Keasling JD (2011) Synthesis of three advanced biofuels from ionic liquid-pretreated switchgrass using engineered Escherichia coli. Proc Natl Acad Sci U S A 108(50):19949–19954

    CAS  PubMed  PubMed Central  Google Scholar 

  • Bothast RJ, Nichols NN, Dien BS (1999) Fermentations with new recombinant organisms. Biotechnol Prog 15(5):867–875

    CAS  PubMed  Google Scholar 

  • Broeker J, Mechelke M, Baudrexl M, Mennerich D, Hornburg D, Mann M, Schwarz WH, Liebl W, Zverlov VV (2018) The hemicellulose-degrading enzyme system of the thermophilic bacterium Clostridium stercorarium: comparative characterisation and addition of new hemicellulolytic glycoside hydrolases. Biotechnol Biofuels 11:229

    PubMed  PubMed Central  Google Scholar 

  • Cao Y, Tan H (2002) Effects of cellulase on the modification of cellulose. Carbohydr Res 337(14):1291–1296

    CAS  PubMed  Google Scholar 

  • Chandrasekaran M, Basheer SM, Chellappan S, Krishna JG, Beena PS (2015) Enzymes in food and beverage production: an overview. In: Chandrasekaran M (ed) Enzymes in food and beverage processing. CRC Press, pp 117–137

  • Chen Y (2011) Development and application of co-culture for ethanol production by co-fermentation of glucose and xylose: a systematic review. J Ind Microbiol Biotechnol 38(5):581–597

    CAS  PubMed  Google Scholar 

  • Chen L, Gu W, Xu H, Yang GL, Shan XF, Chen G, Wang CF, Qian AD (2018) Complete genome sequence of Bacillus velezensis 157 isolated from Eucommia ulmoides with pathogenic bacteria inhibiting and lignocellulolytic enzymes production by SSF. 3 Biotech 8(2):114

    PubMed  PubMed Central  Google Scholar 

  • Chen Y, Cervenka ND, Low AM, Olson DG, Lynd LR (2019) A mutation in the AdhE alcohol dehydrogenase of Clostridium thermocellum increases tolerance to several primary alcohols, including isobutanol, n-butanol and ethanol. Sci Rep 9(1):1736

    Google Scholar 

  • Choi JW, Jeon EJ, Jeong KJ (2018) Recent advances in engineering Corynebacterium glutamicum for utilization of hemicellulosic biomass. Curr Opin Biotechnol 57:17–24

    PubMed  Google Scholar 

  • Choudhary JMS, Nain L, Arora A (2014) Enhanced saccharification of steam-pretreated rice straw by commercial cellulases supplemented with xylanase. J Bioprocess Biotech 4(7):1–6

    Google Scholar 

  • Chutani P, Sharma KK (2016) Concomitant production of xylanases and cellulases from Trichoderma longibrachiatum MDU-6 selected for the deinking of paper waste. Bioprocess Biosyst Eng 39(5):747–758

    CAS  PubMed  Google Scholar 

  • Das A, Paul T, Halder SK, Jana A, Maity C, Das Mohapatra PK, Pati BR, Mondal KC (2013) Production of cellulolytic enzymes by Aspergillus fumigatus ABK9 in wheat bran-rice straw mixed substrate and use of cocktail enzymes for deinking of waste office paper pulp. Bioresour Technol 128:290–296

    CAS  PubMed  Google Scholar 

  • de Almeida MN, Guimarães VM, Falkoski DL, Paes GBT, Ribeiro JI, Visser EM, Alfenas RF, Pereira OL, de Rezende ST (2014) Optimization of endoglucanase and xylanase activities from Fusarium verticillioides for simultaneous saccharification and fermentation of sugarcane bagasse. Appl Biochem Biotechnol 172(3):1332–1346

    PubMed  Google Scholar 

  • de Vries S, Pustjens AM, Schols HA, Hendriks WH, Gerrits WJJ (2012) Improving digestive utilization of fiber-rich feedstuffs in pigs and poultry by processing and enzyme technologies: a review. Anim Feed Sci Technol 178(3):123–138

    Google Scholar 

  • den Haan R, van Rensburg E, Rose SH, Görgens JF, van Zyl WH (2015) Progress and challenges in the engineering of non-cellulolytic microorganisms for consolidated bioprocessing. Curr Opin Biotechnol 33:32–38

    Google Scholar 

  • Dhillon A, Khanna S (2000) Production of a thermostable alkali-tolerant xylanase from Bacillus circulans AB 16 grown on wheat straw. World J Microbiol Biotechnol 16(4):325–327

    CAS  Google Scholar 

  • Dhiman SS, Garg G, Mahajan R, Garg N, Sharma J (2009) ‘Single lay out’and ‘mixed lay out’ enzymatic processes for bio-bleaching of kraft pulp. Bioresour Technol 100(20):4736–4741

    CAS  PubMed  Google Scholar 

  • Dias LM, dos Santos BV, Albuquerque CJB, Baeta BEL, Pasquini D, Baffi MA (2018) Biomass sorghum as a novel substrate in solid-state fermentation for the production of hemicellulases and cellulases by Aspergillus niger and A. fumigatus. J Appl Microbiol 124:708–718

    CAS  PubMed  Google Scholar 

  • Dienes D, Egyhazi A, Reczey K (2004) Treatment of recycled fiber with Trichoderma cellulases. Ind Crop Prod 20(1):11–21

    CAS  Google Scholar 

  • Dutt D, Tyagi CH, Singh RP, Kumar A (2012) Effect of enzyme concoctions on fiber surface roughness and deinking efficiency of sorted office paper. Cellul Chem Technol 46(9):611–623

    CAS  Google Scholar 

  • Dutt D, Tyagi CH, Singh RP, Gautam A, Agnohotri S, Kumar A (2013) Isolation and biochemical characterization of crude xylanase from Coprinus cinereus AT-1 MTCC 9695 and its effectiveness in biodeinking of SOP. Cellul Chem Technol 47(3):203–217

    CAS  Google Scholar 

  • Enzymedica Report (2019) Cellulase is essential for digesting fruits & vegetables. Available online: https://enzymedica.com/blogs/naturaldigestivehealth/cellulase-is-essential-for-digesting-fruits-vegetables

  • Eom SH, Chun YG, Park CE, Kim BK, Lee SH, Park DJ (2018) Application of freeze–thaw enzyme impregnation to produce softened root vegetable foods for elderly consumers. J Texture Stud 49:404–414

    Google Scholar 

  • García-Calvo L, Ullán RV, Fernández-Aguado M, García-Lino AM, Balaña-Fouce R, Barreiro C (2018) Secreted protein extract analyses present the plant pathogen Alternaria alternata as a suitable industrial enzyme toolbox. J Proteome 177:48–64

    Google Scholar 

  • Garg G, Dhiman SS, Mahajan R, Kaur A, Sharma J (2011a) Bleach-boosting effect of crude xylanase from Bacillus stearothermophilus SDX on wheat straw pulp. New Biotechnol 28(1):58–64

    CAS  Google Scholar 

  • Garg G, Mahajan R, Kaur A, Sharma J (2011b) Xylanase production using agro-residue in solid-state fermentation from Bacillus pumilus ASH for biodelignification of wheat straw pulp. Biodegradation 22(6):1143–1154

    CAS  PubMed  Google Scholar 

  • Global animal feed market report (2018–2022) Available online: https://www.technavio.com/report/global-animal-feed-market-analysis-share-2018#

  • Guo H, Hong C, Zheng B, Lu F, Jiang D, Qin W (2017a) Bioflocculants’ production in a biomass-degrading bacterium using untreated corn stover as carbon source and use of bioflocculants for microalgae harvest. Biotechnol Biofuels 10(1):306

    PubMed  PubMed Central  Google Scholar 

  • Guo Z, Duquesne S, Bozonnet S, Nicaud J-M, Marty A, O’Donohue MJ (2017b) Expressing accessory proteins in cellulolytic Yarrowia lipolytica to improve the conversion yield of recalcitrant cellulose. Biotechnol Biofuels 10:298

    PubMed  PubMed Central  Google Scholar 

  • Hasunuma T, Okazaki F, Okai N, Hara KY, Ishii J, Kondo A (2013) A review of enzymes and microbes for lignocellulosic biorefinery and the possibility of their application to consolidated bioprocessing technology. Bioresour Technol 135:513–522

    CAS  PubMed  Google Scholar 

  • Hatakka AI, Mohammadi OK, Lundell TK (1989) The potential of white-rot fungi and their enzymes in the treatment of lignocellulosic feed. Food Biotechnol 3(1):45–58

    CAS  Google Scholar 

  • Henriksson G, Christiernin M, Agnemo R (2005) Monocomponent endoglucanase treatment increases the reactivity of softwood sulphite dissolving pulp. J Ind Microbiol Biotechnol 32(5):211–214

    CAS  PubMed  Google Scholar 

  • Henriksson M, Henriksson G, Berglund LA, Lindström T (2007) An environmentally friendly method for enzyme-assisted preparation of microfibrillated cellulose (MFC) nanofibers. Eur Polym J 43:3434–3441

    CAS  Google Scholar 

  • Hernández C, Milagres AMF, Vázquez-Marrufo G, Muñoz-Páez KM, García-Pérez JA, Alarcón E (2018) An ascomycota coculture in batch bioreactor is better than polycultures for cellulase production. Folia Microbiol (Praha) 63:467–478

    Google Scholar 

  • Hickert LR, de Souza-Cruz PB, Rosa CA, Ayub MAZ (2013) Simultaneous saccharification and co-fermentation of un-detoxified rice hull hydrolysate by Saccharomyces cerevisiae ICV D254 and Spathaspora arborariae NRRL Y-48658 for the production of ethanol and xylitol. Bioresour Technol 143:112–116

    CAS  PubMed  Google Scholar 

  • Hildén L, Väljamäe P, Johansson G (2005) Surface character of pulp fibres studied using endoglucanases. J Biotechnol 118(4):386–397

    PubMed  Google Scholar 

  • Hu J, Arantes V, Saddler JN (2011) The enhancement of enzymatic hydrolysis of lignocellulosic substrates by the addition of accessory enzymes such as xylanase: is it an additive or synergistic effect? Biotechnol Biofuels 4:36

    CAS  PubMed  PubMed Central  Google Scholar 

  • Hua C, Li W, Han W, Wang Q, Bi P, Han C, Zhu L (2018) Characterization of a novel thermostable GH7 endoglucanase from Chaetomium thermophilum capable of xylan hydrolysis. Int J Biol Macromol 117:342–349

    CAS  PubMed  Google Scholar 

  • Husson E, Auxenfans T, Herbaut M, Baralle M, Lambertyn V, Rakotoarivonina H, Rémond C, Sarazin C (2018) Sequential and simultaneous strategies for biorefining of wheat straw using room temperature ionic liquids, xylanases and cellulases. Bioresour Technol 251:280–287

    CAS  PubMed  Google Scholar 

  • Ibarra D, Köpcke V, Larsson PT, Jääskeläinen AS, Ek M (2010) Combination of alkaline and enzymatic treatments as a process for upgrading sisal paper-grade pulp to dissolving-grade pulp. Bioresour Technol 101(19):7416–7423

    CAS  PubMed  Google Scholar 

  • IFIF fact sheet (2019) Available online: https://ifif.org/

  • Ire FS, Ezebuiro V, Ogugbue CJ (2016) Production of bioethanol by bacterial co-culture from agro-waste-impacted soil through simultaneous saccharification and co-fermentation of steam-exploded bagasse. Bioresour Bioprocess 3:26

    Google Scholar 

  • Jacobs CJ, Venditti RA, Joyce TW (1998) Effect of enzyme pretreatments on conventional kraft pulping. TAPPI J 81(2):43–147

    Google Scholar 

  • Jampala P, Tadikamalla S, Preethi M, Ramanujam S, Uppuluri KB (2017) Concurrent production of cellulase and xylanase from Trichoderma reesei NCIM 1186: enhancement of production by desirability-based multi-objective method. 3 Biotech 7:14

    PubMed  PubMed Central  Google Scholar 

  • Jeffries TW, Klungness JH, Sykes MS, Rutledge-Cropsey K (1994) Comparison of enzyme-enhanced with conventional deinking of xerographic and laser-printed paper. TAPPI J 77(4):173–179

    CAS  Google Scholar 

  • Jobbins JM, Franks NE (1997) Enzymatic deinking of mixed office waste: process condition optimization. TAPPI J 80(9):73–78

    CAS  Google Scholar 

  • Jonnadula R, Imran M, Poduval PB, Ghadi SC (2018) Effect of polysaccharide admixtures on expression of multiple polysaccharide-degrading enzymes in Microbulbifer strain CMC-5. Biotechnol Rep 17:93–96

    Google Scholar 

  • Kalyani D, Lee K-M, Kim T-S, Li J, Dhiman SS, Kang YC, Lee JK (2013) Microbial consortia for saccharification of woody biomass and ethanol fermentation. Fuel 107:815–822

    CAS  Google Scholar 

  • Kamaya Y (1996) Role of endoglucanase in enzymatic modification of bleached kraft pulp. J Ferment Bioeng 82(6):549–553

    CAS  Google Scholar 

  • Kamble RD, Jadhav AR (2012) Isolation, purification, and characterization of xylanase produced by a new species of Bacillus in solid state fermentation. Int J Microbiol 2012:683193

    PubMed  PubMed Central  Google Scholar 

  • Karimi K, Emtiazi G, Taherzadeh MJ (2006) Ethanol production from dilute-acid pretreated rice straw by simultaneous saccharification and fermentation with Mucor indicus, Rhizopus oryzae, and Saccharomyces cerevisiae. Enzym Microb Technol 40(1):138–144

    CAS  Google Scholar 

  • Karlsson EN, Schmitz E, Linares-Pastén JA, Adlercreutz P (2018) Endo-xylanases as tools for production of substituted xylooligosaccharides with prebiotic properties. Appl Microbiol Biotechnol 102(21):9081–9088

    Google Scholar 

  • Katsimpouras C, Dedes G, Thomaidis NS, Topakas E (2019) A novel fungal GH30 xylanase with xylobiohydrolase auxiliary activity. Biotechnol Biofuels 12(1):120

    PubMed  PubMed Central  Google Scholar 

  • Kaur A, Mahajan R, Singh A, Garg G, Sharma J (2010) Application of cellulase-free xylano-pectinolytic enzymes from the same bacterial isolate in biobleaching of kraft pulp. Bioresour Technol 101(23):9150–9155

    CAS  PubMed  Google Scholar 

  • Kirk TK, Jeffries TW (1996) Roles for microbial enzymes in pulp and paper processing. In: Jeffries TW, Viikari L (eds) Enzymes for pulp and paper processing. American Chemical Society, Washington, DC, pp 2–14

    Google Scholar 

  • Kramer SJ, Pochapin MB (2012) Gastric phytobezoar dissolution with ingestion of diet coke and cellulose. J Gastroenterol Hepatol 8(11):770

    Google Scholar 

  • Krueger NA, Adesogan AT (2008) Effects of different mixtures of fibrolytic enzymes on digestion and fermentation of bahiagrass hay. Anim Feed Sci Technol 145(1-4):84–94

    CAS  Google Scholar 

  • Kshirsagar SD, Bhalkar BN, Waghmare PR, Saratale GD, Saratale RG, Govindwar SP (2017) Sorghum husk biomass as a potential substrate for production of cellulolytic and xylanolytic enzymes by Nocardiopsis sp. KNU. 3 Biotech 7:163

    PubMed  PubMed Central  Google Scholar 

  • Kuhad RC, Gupta R, Singh A (2011) Microbial cellulases and their industrial applications. Enzyme Res:280696. https://doi.org/10.4061/2011/280696

    Google Scholar 

  • Kumar R, Wyman CE (2009a) Effect of xylanase supplementation of cellulase on digestion of corn stover solids prepared by leading pretreatment technologies. Bioresour Technol 100(18):4203–4213

    CAS  PubMed  Google Scholar 

  • Kumar R, Wyman CE (2009b) Effects of cellulase and xylanase enzymes on the deconstruction of solids from pretreatment of poplar by leading technologies. Biotechnol Prog 25(2):302–314

    CAS  PubMed  Google Scholar 

  • Lal M, Dutt D, Kumar A, Gautam A (2015) Optimization of submerged fermentation conditions for two xylanase producers Corpenellus disseminates MLK- 01NTCC-1180 and MLK-07NTCC-1181 and their biochemical characterization. Cellul Chem Technol 49(5-6):471–483

    CAS  Google Scholar 

  • Le B, Yang SH (2019) Production of prebiotic xylo-oligosaccharide from aqueous ammonia-pretreated rice straw by β-xylosidase of Weissella cibaria. J Appl Microbiol 126(6):1861–1868

    CAS  PubMed  Google Scholar 

  • Lee CK, Darah I, Ibrahim CO (2007) Enzymatic deinking of laser printed office waste papers: some governing parameters on deinking efficiency. Bioresour Technol 98(8):1684–1689

    CAS  PubMed  Google Scholar 

  • Lee CK, Ibrahim D, Omar IC, Rosli WDW (2011) Pilot scale enzymatic deinking of mixed office wastepaper and old newspaper. BioResources 6(4):3809–3823

    CAS  Google Scholar 

  • Li Q, Loman AA, Coffman AM, Ju LK (2017) Soybean hull induced production of carbohydrases and protease among Aspergillus and their effectiveness in soy flour carbohydrate and protein separation. J Biotechnol 248:35–42

    CAS  PubMed  Google Scholar 

  • Lin J, Ndlovu LM, Singh S, Pillay B (1999) Purification and biochemical characteristics of β-D-xylanase from a thermophilic fungus, Thermomyces lanuginosus-SSBP. Biotechnol Appl Biochem 30(1):73–79

    CAS  PubMed  Google Scholar 

  • Lin CW, Wu CH, Tran DT, Shih MC, Li WH, Wu CF (2011) Mixed culture fermentation from lignocellulosic materials using thermophilic lignocellulose-degrading anaerobes. Process Biochem 46(2):489–493

    CAS  Google Scholar 

  • Long C, Cheng Y, Cui J, Liu J, Gan L, Zeng B, Long M (2018) Enhancing cellulase and hemicellulase production in Trichoderma orientalis EU7-22 via knockout of the creA. Mol Biotechnol 60:55–61

    CAS  PubMed  Google Scholar 

  • Lynd LR, van Zyl WH, McBride JE, Laser M (2005) Consolidated bioprocessing of cellulosic biomass: an update. Curr Opin Biotechnol 16(5):577–583

    CAS  PubMed  Google Scholar 

  • Ma K, Ruan Z (2015) Production of a lignocellulolytic enzyme system for simultaneous bio-delignification and saccharification of corn stover employing co-culture of fungi. Bioresour Technol 175:586–593

    CAS  PubMed  Google Scholar 

  • Main GL, Morris JR (2007) Effect of macerating enzymes and postfermentation grape-seed tannin on the color of cynthiana wines. Am J Enol Vitic 58(3):365–372

    CAS  Google Scholar 

  • Marques S, Pala H, Alves L, Amaral-Collaco MT, Gama FM, Gırio FM (2003) Characterisation and application of glycanases secreted by Aspergillus terreus CCMI 498 and Trichoderma viride CCMI 84 for enzymatic deinking of mixed office wastepaper. J Biotechnol 100(3):209–219

    CAS  PubMed  Google Scholar 

  • Masey O’Neill HV, Smith JA, Bedford MR (2014) Multicarbohydrase enzymes for non-ruminants. Asian-Australas J Anim Sci 27(2):290–301

    PubMed  PubMed Central  Google Scholar 

  • Matsakas L, Nitsos C, Raghavendran V, Yakimenko O, Persson G, Olsson E, Rova U, Olsson L, Christakopoulos P (2018) A novel hybrid organosolv: steam explosion method for the efficient fractionation and pretreatment of birch biomass. Biotechnol Biofuels 11:160

    PubMed  PubMed Central  Google Scholar 

  • Mayeli N, Talaeipour M (2010) Effect of different hlb value and enzymatic treatment on the properties of old newspaper deinked pulp. BioResources 5(4):2520–2534

    Google Scholar 

  • Metreveli E, Kachlishvili E, Singer SW, Elisashvili V (2017) Alteration of white-rot basidiomycetes cellulase and xylanase activities in the submerged co-cultivation and optimization of enzyme production by Irpex lacteus and Schizophyllum commune. Bioresour Technol 241:652–660

    CAS  PubMed  Google Scholar 

  • Miao Q, Chen L, Huang L, Tian C, Zheng L, Ni Y (2014) A process for enhancing the accessibility and reactivity of hardwood kraft-based dissolving pulp for viscose rayon production by cellulase treatment. Bioresour Technol 154:109–113

    CAS  PubMed  Google Scholar 

  • Miguel ÂSM, Martins-Meyer TS, da Costa Figueiredo ÉV, Lobo BWP, Dellamora-Ortiz GM (2013) Enzymes in bakery: current and future trends. In: Muzzalupo I (ed) Food industry. IntechOpen. https://doi.org/10.5772/53168

    Google Scholar 

  • Mithra MG, Padmaja G (2017) Strategies for enzyme saving during saccharification of pretreated lignocellulo-starch biomass: effect of enzyme dosage and detoxification chemicals. Heliyon 3:e00384

    CAS  PubMed  PubMed Central  Google Scholar 

  • Mohapatra S, Padhy S, Das Mohapatra PK, Thatoi HN (2018) Enhanced reducing sugar production by saccharification of lignocellulosic biomass, Pennisetum species through cellulase from a newly isolated Aspergillus fumigatus. Bioresour Technol 253:262–272

    CAS  PubMed  Google Scholar 

  • Moraïs S, Barak Y, Hadar Y, Wilson DB, Shoham Y, Lamed R, Bayer EA (2011) Assembly of xylanases into designer cellulosomes promotes efficient hydrolysis of the xylan component of a natural recalcitrant cellulosic substrate. mBio 2(6)

  • Murad HA, Azzaz HH (2010) Cellulase and dairy animal feeding. Biotechnology 9(3):238–256

    CAS  Google Scholar 

  • Nunes MF, da Cunha-Santino MB, Bianchini I (2011) Xylanase and cellulase activities during anaerobic decomposition of three aquatic macrophytes. Braz J Microbiol 42(1):75–83

    CAS  PubMed  PubMed Central  Google Scholar 

  • Olgun O, Altay Y, Yildiz AO (2018) Effects of carbohydrase enzyme supplementation on performance, eggshell quality, and bone parameters of laying hens fed on maize- and wheat-based diets. Br Poult Sci 59(2):211–217

    CAS  PubMed  Google Scholar 

  • Olson DG, McBride JE, Shaw AJ, Lynd LR (2012) Recent progress in consolidated bioprocessing. Curr Opin Biotechnol 23(3):396–405

    CAS  PubMed  Google Scholar 

  • Pala H, Mota M, Gama FM (2004) Enzymatic versus chemical deinking of non-impact ink printed paper. J Biotechnol 108(1):79–89

    CAS  PubMed  Google Scholar 

  • Panesar PS, Chopra HK, Marwaha SS (2010) Fundamentals of enzyme. In: Panesar PS, Chopra HK, Marwaha SS (eds) Enzymes in food processing: fundamentals and potential applications. IK International Pvt Ltd, New Delhi, pp 1–43

    Google Scholar 

  • Parisutham V, Kim TH, Lee SK (2014) Feasibilities of consolidated bioprocessing microbes: from pretreatment to biofuel production. Bioresour Technol 161:431–440

    CAS  PubMed  Google Scholar 

  • Pathak P, Bhardwaj NK, Singh AK (2014) Production of crude cellulase and xylanase from Trichoderma harzianum PPDDN10 NFCCI-2925 and its application in photocopier waste paper recycling. Appl Biochem Biotechnol 172(8):3776–3797

    CAS  PubMed  Google Scholar 

  • Pennacchio A, Ventorino V, Cimini D, Pepe O, Schiraldi C, Inverso M, Faraco V (2018) Isolation of new cellulase and xylanase producing strains and application to lignocellulosic biomasses hydrolysis and succinic acid production. Bioresour Technol 259:325–333

    CAS  PubMed  Google Scholar 

  • Perwez M, Ahmad R, Sardar M (2017) A reusable multipurpose magnetic nanobiocatalyst for industrial applications. Int J Biol Macromol 103:16–24

    CAS  PubMed  Google Scholar 

  • Pinos N, Moreno-Merino S, Congregado M (2015) Phytobezoar by aloe vera as long term complication after oesophagectomy resolved using cellulase. Int J Surg Case Rep 13:37–39

    PubMed  PubMed Central  Google Scholar 

  • Prakash H, Chauhan PS, General T, Sharma AK (2018) Development of eco-friendly process for the production of bioethanol from banana peel using inhouse developed cocktail of thermo-alkali-stable depolymerizing enzymes. Bioprocess Biosyst Eng 41(7):1003–1016

    CAS  PubMed  Google Scholar 

  • Pribowo A, Arantes V, Saddler JN (2012) The adsorption and enzyme activity profiles of specific Trichoderma reesei cellulase/xylanase components when hydrolyzing steam pretreated corn stover. Enzym Microb Technol 50(3):195–203

    CAS  Google Scholar 

  • Puneet P, Bhardwaj NK, Singh AK (2010) Enzymatic deinking of office waste paper: an overview. IPPTA 22(2):83–88

    CAS  Google Scholar 

  • Rahkamo L, Siika-Aho M, Vehviläinen M, Dolk M, Viikari L, Nousiainen P, Buchert J (1996) Modification of hardwood dissolving pulp with purified Trichoderma reesei cellulases. Cellulose 3:153–163

    CAS  Google Scholar 

  • Ramos LP (2003) The chemistry involved in the steam treatment of lignocellulosic materials. Quím Nova 26(6):863–871

    CAS  Google Scholar 

  • Raza A, Bashir S, Tabassum R (2018) Statistical based experimental optimization for co-production of endo-glucanase and xylanase from Bacillus sonorensis BD92 with their application in biomass saccharification. Folia Microbiol (Praha) 64(3):295–305

    Google Scholar 

  • Refat B, Christensen DA, McKinnon JJ, Yang W, Beattie AD, McAllister TA, Eun JS, Abdel-Rahman GA, Yu P (2018) Effect of fibrolytic enzymes on lactational performance, feeding behavior, and digestibility in high-producing dairy cows fed a barley silage-based diet. J Dairy Sci 101(9):7971–7979

    CAS  PubMed  Google Scholar 

  • Roushdy M (2015) Biodeinking of photocopier waste paper effluent by fungal cellulase under solid state fermentation. J Adv Biol Biotechnol 3:190–199

    Google Scholar 

  • Saarinen MT, Lahtinen SJ, Sørensen JF, Tiihonen K, Ouwehand AC, Rautonen N, Morgan A (2012) Treatment of bran containing bread by baking enzymes; effect on the growth of probiotic bacteria on soluble dietary fiber extract in vitro. Biosci Biotechnol Biochem 76(6):1135–1139

    CAS  PubMed  Google Scholar 

  • Saha BC, Cotta MA (2006) Ethanol production from alkaline peroxide pretreated enzymatically saccharified wheat straw. Biotechnol Prog 22(2):449–453

    CAS  PubMed  Google Scholar 

  • Sanhueza C, Carvajal G, Soto-Aguilar J, Lienqueo ME, Salazar O (2018) The effect of a lytic polysaccharide monooxygenase and a xylanase from Gloeophyllum trabeum on the enzymatic hydrolysis of lignocellulosic residues using a commercial cellulase. Enzym Microb Technol 113:75–82

    CAS  Google Scholar 

  • Sawisit A, Jampatesh S, Jantama SS, Jantama K (2018) Optimization of sodium hydroxide pretreatment and enzyme loading for efficient hydrolysis of rice straw to improve succinate production by metabolically engineered Escherichia coli KJ122 under simultaneous saccharification and fermentation. Bioresour Technol 260:348–356

    CAS  PubMed  Google Scholar 

  • Saxena A, Chauhan PS (2016) Role of various enzymes for deinking paper: a review. Crit Rev Biotechnol 37(5):598–612

    PubMed  Google Scholar 

  • Schingoethe DJ, Stegeman GA, Treacher RJ (1999) Response of lactating dairy cows to a cellulase and xylanase enzyme mixture applied to forages at the time of feeding. J Dairy Sci 82(5):996–1003

    CAS  PubMed  Google Scholar 

  • Schuerg T, Prahl JP, Gabriel R, Harth S, Tachea F, Chen CS, Miller M, Masson F, He Q, Brown S, Mirshiaghi LL, Tom LM, Taniore D, Sun N, Pray TR, Singer SW (2017) Xylose induces cellulase production in Thermoascus aurantiacus. Biotechnol Biofuels 10:271

    PubMed  PubMed Central  Google Scholar 

  • Senior DJ, Mayers PP, Miller D, Sutcliffe R, Tan L, Saddler JN (1988) Selective solubilization of xylan in pulp using a purified xylanase from Trichoderma harzianum. Biotechnol Lett 10(12):907–912

    CAS  Google Scholar 

  • Sharma HP, Patel H, Sharma S (2014) Enzymatic extraction and clarification of juice from various fruits—a review. Crit Rev Food Sci Nutr 2(1):1–4

    Google Scholar 

  • Shrinivas D, Savitha G, Raviranjan K, Naik GR (2010) A highly thermostable alkaline cellulase-free xylanase from thermoalkalophilic Bacillus sp. JB 99 suitable for paper and pulp industry: purification and characterization. Appl Biochem Biotechnol 162(7):2049–2057

    CAS  PubMed  Google Scholar 

  • Singh B (2018) Engineering fungal morphology for enhanced production of hydrolytic enzymes by Aspergillus oryzae SBS50 using microparticles. 3 Biotech 8:283

  • Singh A, Yadav RD, Kaur A, Mahajan R (2012) An ecofriendly cost effective enzymatic methodology for deinking of school waste paper. Bioresour Technol 120:322–327

    CAS  PubMed  Google Scholar 

  • Singh A, Bajar S, Bishnoi NR (2014) Enzymatic hydrolysis of microwave alkali pretreated rice husk for ethanol production by Saccharomyces cerevisiae, Scheffersomyces stipites and their co-culture. Fuel 116:4143–4148

    Google Scholar 

  • Singh N, Mathur AS, Gupta RP, Barrow CJ, Tuli D, Puri M (2018) Enhanced cellulosic ethanol production via consolidated bioprocessing by Clostridium thermocellum ATCC 31924. Bioresour Technol 250:860–867

    CAS  PubMed  Google Scholar 

  • Sousa D, Venâncio A, Belo I, Salgado JM (2018) Mediterranean agro-industrial wastes as valuable substrates for lignocellulolytic enzymes and protein production by solid-state fermentation. J Sci Food Agric 98:5248–5256

    CAS  PubMed  Google Scholar 

  • Srinivasan MC, Rele MV (1999) Microbial xylanases for paper industry. Curr Sci 77(1):137–142

    CAS  Google Scholar 

  • Stokes MR (1992) Effects of an enzyme mixture, an inoculant, and their interaction on silage fermentation and dairy production. J Dairy Sci 75(3):764–773

    CAS  PubMed  Google Scholar 

  • Strauss MLA, Jolly NP, Lambrechts MG, Van Rensburg P (2001) Screening for the production of extracellular hydrolytic enzymes by non-Saccharomyces wine yeasts. J Appl Microbiol 91(1):182–190

    CAS  PubMed  Google Scholar 

  • Sujani S, Seresinhe RT (2015) Exogenous enzymes in ruminant nutrition: a review. Asian J Anim Sci 9(3):85–99

    CAS  Google Scholar 

  • Surendran A, Siddiqui Y, Ali NS, Manickam S (2018) Inhibition and kinetic studies of cellulose- and hemicellulose-degrading enzymes of Ganoderma boninense by naturally occurring phenolic compounds. J Appl Microbiol 124:1544–1555

    CAS  PubMed  Google Scholar 

  • Suriyachai N, Weerasaia K, Laosiripojana N, Champreda V, Unrean P (2013) Optimized simultaneous saccharification and co-fermentation of rice straw for ethanol production by Saccharomyces cerevisiae and Scheffersomyces stipitis co-culture using design of experiments. Bioresour Technol 142:171–178

    CAS  PubMed  Google Scholar 

  • Tabka MG, Herpoël-Gimbert I, Monod F, Asther M, Sigoillot JC (2006) Enzymatic saccharification of wheat straw for bioethanol production by a combined cellulase xylanase and feruloyl esterase treatment. Enzym Microb Technol 39(4):897–902

    CAS  Google Scholar 

  • Tan H, Miao R, Liu T, Yang L, Yang Y, Chen C, Lei J, Li Y, He J, Sun Q, Peng W, Gan B, Huang Z (2018) A bifunctional cellulase–xylanase of a new Chryseo bacterium strain isolated from the dung of a straw-fed cattle. Microb Biotechnol 11(2):381–398

    CAS  PubMed  Google Scholar 

  • Tewari S, Dubey KK, Singhal RS (2018) Evaluation and application of prebiotic and probiotic ingredients for development of ready to drink tea beverage. J Food Sci Technol 55(4):1525–1534

    CAS  PubMed  PubMed Central  Google Scholar 

  • Tingting L (2014) Bioenzyme fertilizer. Chinese patent application no. CN105503291A. (https://patents.google.com/patent/CN105503291A/en)

  • Todhanakasem T, Sowatad A, Kanokratana P, Havanapan P, Champreda V (2018) Expression and extracellular secretion of endo-glucanase and xylanase by Zymomonas mobilis. Appl Biochem Biotechnol 187(1):239–252

    PubMed  Google Scholar 

  • Tomme P, Driver DP, Amandoron EA, Miller RC, Antony R, Warren J, Kilburn DG (1995) Comparison of a fungal (family I) and bacterial (family II) cellulose-binding domain. J Bacteriol 177(15):4356–4363

    CAS  PubMed  PubMed Central  Google Scholar 

  • Trudeau DL, Tawfik DS (2019) Protein engineers turned evolutionists—the quest for the optimal starting point. Curr Opin Biotechnol 60:46–52

    CAS  PubMed  Google Scholar 

  • Varghese LM, Agrawal S, Sharma D, Mandhan RP, Mahajan R (2017) Cost-effective screening and isolation of xylano-cellulolytic positive microbes from termite gut and termitarium. 3. Biotech 7(2):108

    Google Scholar 

  • Verma N, Bansal MC, Kumar V (2011) Enzymatic deinking with cellulases: a review. J Solid Waste Technol Manag 37(4):297–306

    Google Scholar 

  • Vinod Kumar N, Rani ME, Gunaseeli R, Kannan ND (2018) Paper pulp modification and deinking efficiency of cellulase-xylanase complex from Escherichia coli SD5. Int J Biol Macromol 111:289–295

    CAS  PubMed  Google Scholar 

  • Virk AP, Puri M, Gupta V, Capalash N, Sharma P (2013) Combined enzymatic and physical deinking methodology for efficient eco-friendly recycling of old newsprint. PLoS One 8(8):e72346

    CAS  PubMed  PubMed Central  Google Scholar 

  • Walia A, Guleria S, Mehta P, Chauhan A, Parkash J (2017) Microbial xylanases and their industrial application in pulp and paper biobleaching: a review. 3 Biotech 7(1):11

    PubMed  PubMed Central  Google Scholar 

  • Wan C, Li Y (2010) Microbial pretreatment of corn stover with Ceriporiopsis subvermispora for enzymatic hydrolysis and ethanol production. Bioresour Technol 101(16):6398–6403

    CAS  PubMed  Google Scholar 

  • Wang Q, Liu S, Yang G, Chen J, Ni Y (2015) Cationic polyacrylamide enhancing cellulase treatment efficiency of hardwood kraft-based dissolving pulp. Bioresour Technol 183:42–46

    CAS  PubMed  Google Scholar 

  • Wang M, Du J, Zhang D, Li X, Zhao J (2017a) Modification of different pulps by homologous overexpression alkali-tolerant endoglucanase in Bacillus subtilis Y106. Sci Rep 7(1):3321

    PubMed  PubMed Central  Google Scholar 

  • Wang Q, Chen L, Yu D, Lin H, Shen Q, Zhao Y (2017b) Excellent waste biomass-degrading performance of Trichoderma asperellum T-1 during submerged fermentation. Sci Total Environ 609:1329–1339

    CAS  PubMed  Google Scholar 

  • Wang J, Gong Y, Zhao S, Liu G (2018a) A new regulator of cellulase and xylanase in the thermophilic fungus Myceliophthora thermophila strain ATCC 42464. 3 Biotech 8:160

    PubMed  PubMed Central  Google Scholar 

  • Wang X, Pei D, Teng Y, Liang J (2018b) Effects of enzymes to improve sensory quality of frozen dough bread and analysis on its mechanism. J Food Sci Technol 55(1):389–398

    CAS  PubMed  Google Scholar 

  • Wazeri A, Elsamadony M, Le Roux S, Peu P, Tawfik A (2018) Potentials of using mixed culture bacteria incorporated with sodium bicarbonate for hydrogen production from water hyacinth. Bioresour Technol 263:365–374

    CAS  PubMed  Google Scholar 

  • Wen Z, Wu M, Lin Y, Yang L, Lin J, Cen P (2014) A novel strategy for sequential co-culture of Clostridium thermocellum and Clostridium beijerinckii to produce solvents from alkali extracted corn cobs. Process Biochem 49(11):1941–1949

    CAS  Google Scholar 

  • Wong KK, Tan LU, Saddler JN (1988) Multiplicity of beta-1, 4-xylanase in microorganisms: functions and applications. Microbiol Rev 52(3):305–317

    CAS  PubMed  PubMed Central  Google Scholar 

  • Wu YB, Ravindran V, Thomas DG, Birtles MJ, Hendriks WH (2004) Influence of phytase and xylanase, individually or in combination, on performance, apparent metabolisable energy, digestive tract measurements and gut morphology in broilers fed wheat-based diets containing adequate level of phosphorus. Br Poult Sci 45(1):76–84

    CAS  PubMed  Google Scholar 

  • Wu X, Zhang J, Xu E, Liu Y, Cheng Y, Addy M, Zhou J, Griffith R, Chen PL, Ruan RR (2016) Microbial hydrolysis and fermentation of rice straw for ethanol production. Fuel 180:679–686

    CAS  Google Scholar 

  • Xu Q, Singh A, Himmel ME (2009) Perspectives and new directions for the production of bioethanol using consolidated bioprocessing of lignocellulose. Curr Opin Biotechnol 20(3):364–371

    CAS  PubMed  Google Scholar 

  • Xu X, Xu Z, Shi S, Lin M (2017) Lignocellulose degradation patterns, structural changes, and enzyme secretion by Inonotus obliquus on straw biomass under submerged fermentation. Bioresour Technol 241:415–423

    CAS  PubMed  Google Scholar 

  • Yadav KS, Naseeruddin S, Prashanthi GS, Sateesh L, Rao LV (2011) Bioethanol fermentation of concentrated rice straw hydrolysate using co-culture of Saccharomyces cerevisiae and Pichia stipitis. Bioresour Technol 102(11):6473–6478

    PubMed  Google Scholar 

  • Yan YS, Zhao S, Liao LS, He QP, Xiong YR, Wang L, Li CX, Feng JX (2017) Transcriptomic profiling and genetic analyses reveal novel key regulators of cellulase and xylanase gene expression in Penicillium oxalicum. Biotechnol Biofuels 10:279

    PubMed  PubMed Central  Google Scholar 

  • Yang M, Zhang J, Kuittinen S, Vepsäläinen J, Soininen P, Keinänen M, Pappinen A (2015) Enhanced sugar production from pretreated barley straw by additive xylanase and surfactants in enzymatic hydrolysis for acetone-butanol-ethanol fermentation. Bioresour Technol 189:131–137

    CAS  PubMed  Google Scholar 

  • Ye Y, Li X, Cao Y, Du J, Chen S, Zhao J (2017) A β-xylosidase hyper-production Penicillium oxalicum mutant enhanced ethanol production from alkali-pretreated corn stover. Bioresour Technol 245:734–742

    CAS  PubMed  Google Scholar 

  • Zhang YHP, Lynd LR (2004) Towards an aggregated understanding of enzymatic hydrolysis of cellulose: noncomplexed cellulase systems. Biotechnol Bioeng 88(7):797–824

    CAS  PubMed  Google Scholar 

  • Zhang M, Li Z, Yang R (2017) Preparation of xylanase loaded biomass-based deinking agents and their application in secondary fiber recycling. BioResources 12(2):2818–2829

    CAS  Google Scholar 

  • Zhang W, Wu S, Cai L, Liu X, Wu H, Xin F, Zhang M, Jiang M (2018) Improved treatment and utilization of rice straw by Coprinopsis cinerea. Appl Biochem Biotechnol 184:616–629

    CAS  PubMed  Google Scholar 

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Acknowledgments

The authors sincerely appreciate the help of Ms. Sarbani Chakraborti, Institute of Microbial Technology, for her help in drafting the manuscript.

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This work is supported by funding from the Council of Scientific and Industrial Research (CSIR) and the Department of Science and Technology (DST), India.

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  1. CSIR-Institute of Microbial Technology (IMTech), Sector-39A, Chandigarh, 160036, India

    Priyanka Bajaj

  2. Department of Biotechnology, Kurukshetra University, Kurukshetra, 136119, India

    Ritu Mahajan

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Bajaj, P., Mahajan, R. Cellulase and xylanase synergism in industrial biotechnology. Appl Microbiol Biotechnol 103, 8711–8724 (2019). https://doi.org/10.1007/s00253-019-10146-0

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