Abstract
Lactobacilli are recognized as probiotics on account of their health-promoting effects in the host. The aim of this review is to summarize current knowledge of the mechanisms of the adaption factors and main functions of lactobacilli that exert health-promoting effects in the host and to discuss important applications in animal and human health. The adaption mechanisms of lactobacilli facilitate interactions with the host and directly contribute to the beneficial nutritional, physiological, microbiological, and immunological effects in the host. Besides, the application of probiotic lactobacilli will increase our understanding of practical uses based on the roles of these organisms in immunoregulation, antipathogenic activities, and enhancement of the epithelial barrier.
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This work was supported by grants from the National Key Research and Development Program of China (grant no. 2017YFD0501104), the National Natural Science Foundation of China (grant no. 31772780), the Key Technology R&D Program of Gansu Province of China (grant no. 1604NKCA045-2), and the China Agriculture Research System (grant no. CARS-35).
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Zhang, Z., Lv, J., Pan, L. et al. Roles and applications of probiotic Lactobacillus strains. Appl Microbiol Biotechnol 102, 8135–8143 (2018). https://doi.org/10.1007/s00253-018-9217-9
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DOI: https://doi.org/10.1007/s00253-018-9217-9