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Spotlights on advances in mycotoxin research

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Abstract

A remarkable feature of filamentous fungi is their ability to produce small yet structurally complex and often bioactive natural products. In this mini-review, we cover advances in the research on fungal secondary metabolites, particularly mycotoxins, and focus on biosynthetic aspects as well as on the complex regulatory mechanisms which control the expression of biosynthetic genes. We also highlight the increasing impact of genomics and transcriptomics, which help explore the realm of secondary metabolism of fungi.

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Acknowledgments

M.B. acknowledges a predoctoral fellowship of the Jena School of Microbial Communication (JSMC). Research in D.H.s laboratory is supported by the Leibniz-Institute for Infection Biology and Natural Product research—Hans-Knöll-Institute, by the Friedrich-Schiller-Universität Jena, and by the International Leibniz Research School for Microbial Interaction (ILRS Mibintact).

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  1. Department Pharmaceutical Biology at the Hans-Knöll-Institute, Friedrich-Schiller-Universität Jena, Beutenbergstrasse 11a, 07745, Jena, Germany

    Markus Bohnert, Barbara Wackler & Dirk Hoffmeister

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  1. Markus Bohnert
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  2. Barbara Wackler
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  3. Dirk Hoffmeister
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Correspondence to Dirk Hoffmeister.

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Bohnert, M., Wackler, B. & Hoffmeister, D. Spotlights on advances in mycotoxin research. Appl Microbiol Biotechnol 87, 1–7 (2010). https://doi.org/10.1007/s00253-010-2565-8

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  • DOI: https://doi.org/10.1007/s00253-010-2565-8

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