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Production of rhamnolipids by Pseudomonas aeruginosa

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Abstract

Pseudomonas aeruginosa produces glycolipidic surface-active molecules (rhamnolipids) which have potential biotechnological applications. Rhamnolipids are produced by P. aeruginosa in a concerted manner with different virulence-associated traits. Here, we review the rhamnolipids biosynthetic pathway, showing that it has metabolic links with numerous bacterial products such as alginate, lipopolysaccharide, polyhydroxyalkanoates, and 4-hydroxy-2-alkylquinolines (HAQs). We also discuss the factors controlling the production of rhamnolipids and the proposed roles this biosurfactant plays in P. aeruginosa lifestyle.

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Authors and Affiliations

  1. Departamento de Bioprocesos y Biocatálisis, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Mexico City, Mexico

    Gloria Soberón-Chávez

  2. INRS-Institut Armand-Frappier, Université du Québec, Laval, Quebec, Canada

    François Lépine & Eric Déziel

  3. Apdo, Postal 70228, 04510, Mexico City, Mexico

    Gloria Soberón-Chávez

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  1. Gloria Soberón-Chávez
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  2. François Lépine
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  3. Eric Déziel
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Correspondence to Gloria Soberón-Chávez.

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Soberón-Chávez, G., Lépine, F. & Déziel, E. Production of rhamnolipids by Pseudomonas aeruginosa . Appl Microbiol Biotechnol 68, 718–725 (2005). https://doi.org/10.1007/s00253-005-0150-3

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