Abstract
We present measurements of the effective spontaneous curvature of fluid lipid bilayers as a function of trans-bilayer asymmetry. Experiments are performed on micrometer-scale vesicles in sugar solutions with varying species across the membrane. There are two effects leading to a preferred curvature of such a vesicle. The spontaneous curvatures of the two monolayers as well as their area difference combine into an effective spontaneous curvature of the membrane. Our technique for measuring this parameter allows us to use vesicle morphology as a probe for general membrane-solute interactions affecting elasticity.
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Received: 3 June 1998 / Revised version: 18 August 1998 / Accepted: 21 August 1998
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Döbereiner, HG., Selchow, O. & Lipowsky, R. Spontaneous curvature of fluid vesicles induced by trans-bilayer sugar asymmetry. Eur Biophys J 28, 174–178 (1999). https://doi.org/10.1007/s002490050197
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DOI: https://doi.org/10.1007/s002490050197