Skip to main content
Log in

Impact of a fast free-breathing 3-T abdominal MRI protocol on improving scan time and image quality for pediatric patients with tuberous sclerosis complex

  • Original Article
  • Published:
Pediatric Radiology Aims and scope Submit manuscript

Abstract

Background

Magnetic resonance imaging (MRI) of the abdomen can be especially challenging in pediatric patients because of image quality degradation from respiratory motion. Abdominal MR protocols tailored for free-breathing children can potentially improve diagnostic image quality and reduce scan time.

Objective

To evaluate the performance of a free-breathing 3-T MRI protocol for renal evaluation in pediatric patients with tuberous sclerosis complex (TSC).

Materials and methods

A single institution, Institutional Review Board-approved, retrospective database query identified pediatric TSC patients who underwent a free-breathing 3-T MR abdominal protocol including radial and respiratory-triggered pulse sequences and who also had a prior abdominal MRI on the same scanner using a traditional MR protocol utilizing signal averaging and Cartesian k-space sampling. Scan times and use of sedation were recorded. MR image quality was compared between the two protocols using a semiquantitative score for overall image quality and sharpness.

Results

Forty abdominal MRI studies in 20 patients were evaluated. The mean scan time of the fast free-breathing protocol was significantly lower (mean: 42.5±9.8 min) compared with the traditional protocol (58.7±11.7 min; P=<0.001). Image sharpness was significantly improved for radial T2-weighted and T1-weighted triggered Dixon and radial T1-weighted fat-suppressed post-contrast images in the free-breathing protocol, while image quality was significantly higher on radial and Dixon T1-weighted sequences.

Conclusion

A free-breathing abdominal MR protocol in pediatric TSC patients decreases scan time and improves image quality and should be considered more widely for abdominal MRI in children.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Hinton R, Prakash A, Romp RL et al (2014) Cardiovascular manifestations of tuberous sclerosis complex and summary of the revised diagnostic criteria and surveillance and management recommendations from the international tuberous sclerosis consensus group. J Am Heart Assoc 3:e001493

    Article  Google Scholar 

  2. Northrup H, Krueger DA, International Tuberous Sclerosis Complex Consensus Group (2013) Tuberous sclerosis complex diagnostic criteria update: recommendations of the 2012 international tuberous sclerosis complex consensus conference. Pediatr Neurol 49:243–254

    Article  Google Scholar 

  3. Sasiwimonphan K, Takahashi N, Leibovich B et al (2012) Small (< 4 cm) renal mass: differentiation of angiomyolipoma without visible fat from renal cell carcinoma utilizing MR imaging. Radiology 263:160–168

    Article  Google Scholar 

  4. Jaimes C, Gee MS (2016) Strategies to minimize sedation in pediatric body magnetic resonance imaging. Pediatr Radiol 46:916–927

    Article  Google Scholar 

  5. Lim RS, Flood TA, McInnes MDF et al (2018) Renal angiomyolipoma without visible fat: can we make the diagnosis using CT and MRI? Eur Radiol 28:542–553

    Article  Google Scholar 

  6. Farrell C, Noyes SL, Tourojman M, Lane BR (2015) Renal angiomyolipoma: preoperative identification of atypical fat-poor AML. Curr Urol Rep 16:12

    Article  Google Scholar 

  7. Chandarana H, Block TK, Rosenkrantz AB et al (2011) Free-breathing radial 3D fat-suppressed T1-weighted gradient echo sequence: a viable alternative for contrast-enhanced liver imaging in patients unable to suspend respiration. Investig Radiol 46:648–653

    Article  Google Scholar 

  8. Pipe JG (1999) Motion correction with PROPELLER MRI: application to head motion and free-breathing cardiac imaging. Magn Reson Med 42:963–969

    Article  CAS  Google Scholar 

  9. Hirokawa Y, Isoda H, Maetani YS et al (2008) MRI artifact reduction and quality improvement in the upper abdomen with PROPELLER and prospective acquisition correction (PACE) technique. AJR Am J Roentgenol 191:1154–1158

    Article  Google Scholar 

  10. Cruz G, Atkinson D, Buerger C et al (2016) Accelerated motion corrected three-dimensional abdominal MRI using total variation regularized SENSE reconstruction. Magn Reson Med 75:1484–1498

    Article  Google Scholar 

  11. Landis JR, Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33:159–174

    Article  CAS  Google Scholar 

  12. Jaimes C, Kirsch JE, Gee MS (2018) Fast, free-breathing and motion-minimized techniques for pediatric body magnetic resonance imaging. Pediatr Radiol 48:1197–1208

    Article  Google Scholar 

  13. Chandarana H, Feng L, Block TK et al (2013) Free-breathing contrast-enhanced multiphase MRI of the liver using a combination of compressed sensing, parallel imaging, and golden-angle radial sampling. Investig Radiol 48:10–16

    Article  Google Scholar 

  14. Vanderby SA, Babyn PS, Carter MW et al (2010) Effect of anesthesia and sedation on pediatric MR imaging patient flow. Radiology 256:229–237

    Article  Google Scholar 

  15. Uffman JC, Tumin D, Raman V et al (2017) MRI utilization and the associated use of sedation and anesthesia in a pediatric ACO. J Am Coll Radiol 14:924–930

    Article  Google Scholar 

  16. Robertson RL, Silk S, Ecklund K et al (2018) Imaging optimization in children. J Am Coll Radiol 15:440–443

    Article  Google Scholar 

  17. Flick R, Katusic SK, Colligan RC et al (2011) Cognitive and behavioral outcomes after early exposure to anesthesia and surgery. Pediatrics 128:e1053–e1061

    Article  Google Scholar 

  18. Zhang H, Du L, Du Z et al (2015) Association between childhood exposure to single general anesthesia and neurodevelopment: a systematic review and meta-analysis of cohort study. J Anesth 29:749–757

    Article  Google Scholar 

  19. Gale EM, Caravan P, Rao AG et al (2017) Gadolinium-based contrast agents in pediatric magnetic resonance imaging. Pediatr Radiol 47:507–521

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Rene Balza.

Ethics declarations

Conflicts of interest

Keith Heberlein is an employee of Siemens Medical Solutions, USA.

Additional information

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Balza, R., Jaimes, C., Risacher, S. et al. Impact of a fast free-breathing 3-T abdominal MRI protocol on improving scan time and image quality for pediatric patients with tuberous sclerosis complex. Pediatr Radiol 49, 1788–1797 (2019). https://doi.org/10.1007/s00247-019-04496-0

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00247-019-04496-0

Keywords

Navigation