Skip to main content
SpringerLink
Log in

Transient isolated lesion of the splenium associated with clinically mild influenza encephalitis

  • Case Report
  • Published:
Pediatric Radiology Aims and scope Submit manuscript

Abstract

Transient isolated lesions of the splenium with restricted diffusion are rare in the pediatric population. We report two such cases with influenza-associated encephalitis/encephalopathy (IAEE). These reversible isolated central splenial lesions are not specific for IAEE, but the notable feature associated with this specific presentation is a comparatively milder form of encephalitis that resolves clinically and radiologically within a short time.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Bulakbasi N, Kocaoglu M, Tayfun C et al (2006) Transient splenial lesion of the corpus callosum in clinically mild influenza-associated encephalitis/encephalopathy. AJNR 27:1983–1986

    PubMed  CAS  Google Scholar 

  2. Takanashi J, Barkovich AJ, Yamaguchi K et al (2004) Influenza encephalopathy with a reversible lesion in the splenium of the corpus callosum. AJNR 25:798–802

    PubMed  Google Scholar 

  3. Tada H, Takanashi J, Barkovich AJ et al (2004) Clinically mild encephalitis/encephalopathy with a reversible splenial lesion. Neurology 63:1854–1858

    PubMed  CAS  Google Scholar 

  4. Matsukara K, Kodera M, Nigami H et al (2007) Reversible splenial lesion in influenza virus encephalopathy. Pediatr Neurol 6:431–434

    Article  Google Scholar 

  5. Ritsuyo K, Hirokazu T, Akio N et al (2002) Transient MR signal changes in the splenium of the corpus callosum in rotavirus encephalopathy: value of diffusion-weighted imaging. J Comput Assist Tomogr 26:825–828

    Article  Google Scholar 

  6. Kobuchi N, Tsukahara H, Kawamura Y et al (2003) Reversible diffusion weighted MR findings of Salmonella enteritidis-associated encephalopathy. Eur Neurol 49:182–184

    Article  PubMed  CAS  Google Scholar 

  7. Kim SS, Chang K-H, Kim ST et al (1999) Focal lesion in the splenium of the corpus callosum in epileptic patients: antiepileptic drug toxicity? AJNR 20:125–129

    PubMed  CAS  Google Scholar 

  8. Takanashi J, Barkovich AJ, Shiihara T et al (2006) Widening spectrum of a reversible splenial lesion with transiently reduced diffusion. AJNR 27:836–838

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Radiology and Medical Imaging, Dayton Children’s Medical Center, 1 Children’s Plaza, Dayton, OH, 45404, USA

    Srinivas Ganapathy, Elizabeth H. Ey & Barbara J. Wolfson

  2. Department of Neurology, Dayton Children’s Medical Center, Dayton, OH, USA

    Nadir Khan

Authors
  1. Srinivas Ganapathy
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Elizabeth H. Ey
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Barbara J. Wolfson
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Nadir Khan
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Srinivas Ganapathy.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ganapathy, S., Ey, E.H., Wolfson, B.J. et al. Transient isolated lesion of the splenium associated with clinically mild influenza encephalitis. Pediatr Radiol 38, 1243–1245 (2008). https://doi.org/10.1007/s00247-008-0949-z

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00247-008-0949-z

Keywords

Search

Navigation