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Masked Isolated Nocturnal Hypertension in Children and Young Adults

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Abstract

Isolated nocturnal hypertension (INH) is characterized by normal daytime blood pressure (BP) and elevated nighttime BP diagnosed by ambulatory BP monitoring. Masked isolated nocturnal hypertension (MINH) is a subtype of INH in which office BP is normal. We studied the frequency and characteristics of INH and MINH in children and young adults. One hundred and ninety-eight subjects seen by the pediatric nephrology service were studied retrospectively. Isolated nocturnal hypertension (INH) and MINH were diagnosed according to daytime and nighttime ABP and office BP in the case of the latter. One hundred and eighteen subjects (60%) had normotension, 6 (3%) had isolated daytime hypertension, 32 (16%) had INH, and 42 (21%) had day–night hypertension. Sixteen subjects had MINH (8.1%). The underlying diseases of MINH were as follows: no underlying disease 9 (56%), renal disease 6 (38%), and endocrine disease 1 (6%). There was no significant difference in the underlying disease, gender, age, and BMI between MINH and INH with elevated office BP. In conclusion, MINH is present in children and young adults. Since there were no specific features for MINH, screening with ambulatory or home BP monitoring during sleep may be appropriate.

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Authors and Affiliations

  1. Department of Pediatrics, Tokyo Medical Center, Tokyo, Japan

    Hisayo Fujita

  2. Department of Pediatrics, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan

    Midori Awazu

  3. Matsuoka Clinic, Kanagawa, Japan

    Seiji Matsuoka

Authors
  1. Hisayo Fujita
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  2. Seiji Matsuoka
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  3. Midori Awazu
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Correspondence to Midori Awazu.

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The authors declare that they have no conflict of interest.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and national ethical guidelines for medical and health research involving human subjects and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was not obtained but the option of opting out was provided as approved by the ethics committee of Keio University School of Medicine.

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Fujita, H., Matsuoka, S. & Awazu, M. Masked Isolated Nocturnal Hypertension in Children and Young Adults. Pediatr Cardiol 39, 66–70 (2018). https://doi.org/10.1007/s00246-017-1728-0

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  • DOI: https://doi.org/10.1007/s00246-017-1728-0

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