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Environmental Factors and Rheumatic Heart Disease in Fiji

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Abstract

Rheumatic heart disease (RHD) is an important cause of cardiac morbidity and mortality globally, particularly in the Pacific region. Susceptibility to RHD is thought to be due to genetic factors that are influenced by environmental factors, such as crowding and poverty. However, there are few data relating to these environmental factors in the Pacific region. We conducted a case-control study of 80 cases of RHD with age- and sex-matched controls in Fiji using a questionnaire to investigate associations of RHD with a number of environmental factors. There was a trend toward increased risk of RHD in association with poor-quality housing and lower socioeconomic status, but only one factor, maternal unemployment, reached statistical significance (OR 2.6, 95% confidence interval 1.2–5.8). Regarding crowding, little difference was observed between the two groups. Although our data do not allow firm conclusions, they do suggest that further studies of socioeconomic factors and RHD in the Pacific are warranted. They also suggest that genetic studies would provide an insight into susceptibility to RHD in this population.

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Acknowledgments

We thank the Fiji Group A Streptococcal Project team, Mere Gunaivalu, Frances Matanatabu, Tomasi Matamusuka, Lai Matatolu, and Kavita Prasad, for their assistance. We also thank the children and their families for participating in the study. Joelle Dobson was the recipient of a bursary from St. George’s University Of London, UK.

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Authors and Affiliations

  1. St. George’s University of London, London, UK

    Joelle Dobson

  2. Centre for International Child Health, University of Melbourne, Melbourne, VIC, Australia

    Andrew C. Steer & Samantha Colquhoun

  3. Menzies School of Health Research, Darwin, NT, Australia

    Samantha Colquhoun

  4. Colonial War Memorial Hospital, Fiji Ministry of Health, Suva, Fiji Islands

    Joseph Kado

Authors
  1. Joelle Dobson
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  2. Andrew C. Steer
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  3. Samantha Colquhoun
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  4. Joseph Kado
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Corresponding author

Correspondence to Joseph Kado.

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Dobson, J., Steer, A.C., Colquhoun, S. et al. Environmental Factors and Rheumatic Heart Disease in Fiji. Pediatr Cardiol 33, 332–336 (2012). https://doi.org/10.1007/s00246-011-0139-x

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  • DOI: https://doi.org/10.1007/s00246-011-0139-x

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