Abstract
Sumatriptan is widely used in the treatment of acute attacks of cluster headache. It is a serotonin-1 (5HT-1) agonist. Several studies have reported an association between sumatriptan use and myocardial infarction, possibly due to the generalized vasoconstrictive nature of this agent. We report a 16-year-old male patient presenting with acute inferior myocardial infarction after sumatriptan use without any known risk factors of coronary artery disease.
Similar content being viewed by others
References
HE Connor W Fenuik PP Humphrey (1989) ArticleTitle5-Hydroxy-tryptamine contracts human coronary arteries predominantly via 5-HT2 receptor activation Eur J Pharmacol 161 91–94 Occurrence Handle2542039 Occurrence Handle10.1016/0014-2999(89)90184-2 Occurrence Handle1:CAS:528:DyaL1MXhs1KlsLs%3D
KM Kelly (1995) ArticleTitleCardiac arrest following use of sumatriptan Neurology 45 1211–1213 Occurrence Handle7783891 Occurrence Handle1:STN:280:ByqA3czivV0%3D
PD Maclntyre B Bhargava KJ Hogg JD Gemmill WS Hillis (1993) ArticleTitleEffect of subcutaneous sumatriptan, a selective 5HT1 agonist, on the systemic, pulmonary, and coronary circulation Circulation 87 401–405
L Mueller RM Gallagher CA Ciervo (1996) ArticleTitleVasospasm-induced myocardial infarction with sumatriptan Headache 36 329–31 Occurrence Handle8682677 Occurrence Handle10.1046/j.1526-4610.1996.3605329.x Occurrence Handle1:STN:280:BymB28jnvFU%3D
P O'Conner P Gladstone (1995) ArticleTitleOral sumatriptan-associated transmural myocardial infarction Neurology 45 2274–2276
JP Ottervanger HJ Paalman GL Boxma BH Stricker (1993) ArticleTitleTransmural myocardial infarction with sumatriptan Lancet 341 861–862 Occurrence Handle8096565 Occurrence Handle10.1016/0140-6736(93)93064-8 Occurrence Handle1:STN:280:ByyB3Mfjs1A%3D
JP Ottervanger BH Stricker (1995) ArticleTitleCardiovascular adverse reactions to sumatriptan: cause for concern? CNS Drugs 3 90–98 Occurrence Handle10.2165/00023210-199503020-00002
JP Ottervanger HA Valkenburg DE Grobbee BH Stricker (1997) ArticleTitleCharacteristics and determinants of sumatriptan-associated chest pain Arch Neurol 54 1387–1392 Occurrence Handle9362987 Occurrence Handle1:STN:280:DyaK1c%2FivFaktg%3D%3D
WH Visser NM Jaspers RH Vriend ParticleDe MD Ferrari (1996) ArticleTitleChest symptoms after sumatriptan: a two-year clinical practice review in 735 consecutive migraine patients Cephalalgia 16 554–559 Occurrence Handle8980858 Occurrence Handle1:STN:280:ByiC3srjt1U%3D
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Erbilen, E., Ozhan, H., Akdemir, R. et al. A Case of Myocardial Infarction with Sumatriptan Use. Pediatr Cardiol 26, 464–466 (2005). https://doi.org/10.1007/s00246-004-0768-4
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00246-004-0768-4