Skip to main content

Advertisement

Log in

A Case of Myocardial Infarction with Sumatriptan Use

  • Published:
Pediatric Cardiology Aims and scope Submit manuscript

Abstract

Sumatriptan is widely used in the treatment of acute attacks of cluster headache. It is a serotonin-1 (5HT-1) agonist. Several studies have reported an association between sumatriptan use and myocardial infarction, possibly due to the generalized vasoconstrictive nature of this agent. We report a 16-year-old male patient presenting with acute inferior myocardial infarction after sumatriptan use without any known risk factors of coronary artery disease.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1
Figure 2

Similar content being viewed by others

References

  1. HE Connor W Fenuik PP Humphrey (1989) ArticleTitle5-Hydroxy-tryptamine contracts human coronary arteries predominantly via 5-HT2 receptor activation Eur J Pharmacol 161 91–94 Occurrence Handle2542039 Occurrence Handle10.1016/0014-2999(89)90184-2 Occurrence Handle1:CAS:528:DyaL1MXhs1KlsLs%3D

    Article  PubMed  CAS  Google Scholar 

  2. KM Kelly (1995) ArticleTitleCardiac arrest following use of sumatriptan Neurology 45 1211–1213 Occurrence Handle7783891 Occurrence Handle1:STN:280:ByqA3czivV0%3D

    PubMed  CAS  Google Scholar 

  3. PD Maclntyre B Bhargava KJ Hogg JD Gemmill WS Hillis (1993) ArticleTitleEffect of subcutaneous sumatriptan, a selective 5HT1 agonist, on the systemic, pulmonary, and coronary circulation Circulation 87 401–405

    Google Scholar 

  4. L Mueller RM Gallagher CA Ciervo (1996) ArticleTitleVasospasm-induced myocardial infarction with sumatriptan Headache 36 329–31 Occurrence Handle8682677 Occurrence Handle10.1046/j.1526-4610.1996.3605329.x Occurrence Handle1:STN:280:BymB28jnvFU%3D

    Article  PubMed  CAS  Google Scholar 

  5. P O'Conner P Gladstone (1995) ArticleTitleOral sumatriptan-associated transmural myocardial infarction Neurology 45 2274–2276

    Google Scholar 

  6. JP Ottervanger HJ Paalman GL Boxma BH Stricker (1993) ArticleTitleTransmural myocardial infarction with sumatriptan Lancet 341 861–862 Occurrence Handle8096565 Occurrence Handle10.1016/0140-6736(93)93064-8 Occurrence Handle1:STN:280:ByyB3Mfjs1A%3D

    Article  PubMed  CAS  Google Scholar 

  7. JP Ottervanger BH Stricker (1995) ArticleTitleCardiovascular adverse reactions to sumatriptan: cause for concern? CNS Drugs 3 90–98 Occurrence Handle10.2165/00023210-199503020-00002

    Article  Google Scholar 

  8. JP Ottervanger HA Valkenburg DE Grobbee BH Stricker (1997) ArticleTitleCharacteristics and determinants of sumatriptan-associated chest pain Arch Neurol 54 1387–1392 Occurrence Handle9362987 Occurrence Handle1:STN:280:DyaK1c%2FivFaktg%3D%3D

    PubMed  CAS  Google Scholar 

  9. WH Visser NM Jaspers RH Vriend ParticleDe MD Ferrari (1996) ArticleTitleChest symptoms after sumatriptan: a two-year clinical practice review in 735 consecutive migraine patients Cephalalgia 16 554–559 Occurrence Handle8980858 Occurrence Handle1:STN:280:ByiC3srjt1U%3D

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to H. Ozhan.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Erbilen, E., Ozhan, H., Akdemir, R. et al. A Case of Myocardial Infarction with Sumatriptan Use. Pediatr Cardiol 26, 464–466 (2005). https://doi.org/10.1007/s00246-004-0768-4

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00246-004-0768-4

Keywords

Navigation