Skip to main content

Advertisement

SpringerLink
Log in

Association of Clinical Characteristics of Unexplained Syncope with the Outcome of Head-Up Tilt Tests in Children

  • Published:
Pediatric Cardiology Aims and scope Submit manuscript

Abstract

The aim of this study was to clarify the association of clinical characteristics of unexplained syncope with the outcome of the head-up tilt test (HUT) in children. A total of 47 patients with unexplained syncope were classified into two groups according to their outcomes of HUT: the positive response group and the negative response group. We reviewed their clinical data as well as the results of HUT and analyzed them with logistic regression method. The results showed that the incidence of positive responses to HUT was higher in girls than in boys (8/22 vs 10/7, p < 0.05). Compared with fainted children younger than 12 years of age, 12- to 16-year-old adolescents with unexplained syncope had a high positive outcome of HUT (30 vs 72.9%, p < 0.05). Compared with fainted children with negative response of HUT, children with positive response to HUT often had syncope in special circumstances (e.g., prolonged standing, anxiety and fright, and morning exercise), and they often had prodrome, such as pallor, lightheadedness, and nausea (28/30 vs 8/17, p < 0.05). However, the number and duration of syncopal spells did not relate to the positive responses to HUT. The logistic regression analysis showed that three factors significantly influenced the outcome of HUT: predisposing factors of syncope, prodrome of syncope, and age (p < 0.05; OR = 32.9434, 17.7281, and 2.7842, respectively). Hence, if pubertal girls with unexplained syncope had clear predisposing factors and prodromes, they were likely to have positive responses to HUT, and they were likely to be clinically considered as having vasovagal syncope.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. P Blair MD Grubb (1999) ArticleTitlePathophysiology and differential diagnosis of neurocardiogenic syncope. Am J Cardiol 84 3Q–9Q Occurrence Handle10568555

    PubMed  Google Scholar 

  2. DJ Driscoll SJ Jacobsen CJ Porter PC Wollan (1997) ArticleTitleSyncope in children and adolescents. J Am Coll Cardiol 29 1039–1045 Occurrence Handle10.1016/S0735-1097(97)00020-X Occurrence Handle1:STN:280:ByiB2cvkt1U%3D Occurrence Handle9120157

    Article  CAS  PubMed  Google Scholar 

  3. CL Johnsrude (2000) ArticleTitleCurrent approach to pediatric syncope. Pediatr Cardiol 21 522–531 Occurrence Handle10.1007/s002460010130 Occurrence Handle1:STN:280:DC%2BD3M%2Fltl2rtA%3D%3D Occurrence Handle11050276

    Article  CAS  PubMed  Google Scholar 

  4. D Junbao M Zhao L Wanzhen et al. (1999) ArticleTitleA study on head-up tilt test for the diagnosis of unexplained syncope in children. Cardiovasc Eng 4 8–10

    Google Scholar 

  5. MM Levine (1999) ArticleTitleNeurally mediated syncope in children: results of tilt testing, treatment, and long-term follow-up. Pediatr Cardiol 20 331–335 Occurrence Handle10.1007/s002469900479 Occurrence Handle1:STN:280:DyaK1MzntlCisA%3D%3D Occurrence Handle10441686

    Article  CAS  PubMed  Google Scholar 

  6. LA Lipsiz J Mietus GB Moody AL Goldberger (1990) ArticleTitleSpectral characteristics of heart rate variability before and during postural tilt: relations to aging and risk of syncope. Circulation 81 1830–1810

    Google Scholar 

  7. G Muller BJ Deal JF Strasburger DW Benson Jr (1993) ArticleTitleUsefulness of metoprolol for unexplained syncope and positive response to tilt testing in young persons. Am J Cardiol 71 592–595 Occurrence Handle10.1016/0002-9149(93)90517-G Occurrence Handle1:STN:280:ByyC2srjsVE%3D Occurrence Handle8438747

    Article  CAS  PubMed  Google Scholar 

  8. S Richard M Daniel (1999) ArticleTitleIndication, methodology, and classification of results of tilt-table testing. Am J Cardiol 84 10Q–16Q Occurrence Handle10.1016/S0002-9149(99)00692-X Occurrence Handle10568556

    Article  PubMed  Google Scholar 

  9. JK Ronald (1999) syncope. P Gillette A Garson (Eds) Clinical Pediatric Arrthythmias, 2nd edn. Saunders Philadelphia 251–286

    Google Scholar 

  10. S Rose ML Koshman R McDonald et al. (1996) ArticleTitleHealth-related quality of life in patients with neuromediated syncope. Can J Cardiol 12 131–138

    Google Scholar 

  11. RS Sheldon (1994) ArticleTitleEffects of aging on response to isoprotenol tilt-table testing in patients with syncope. J Am Coll Cardiol 19 773–779

    Google Scholar 

  12. R Sheldon (1994) ArticleTitleEffects of aging on responses to isoprotenol tilt-table testing in patients with syncope. Am J Cardiol 7 459–463 Occurrence Handle10.1016/0002-9149(94)90903-2

    Article  Google Scholar 

  13. R Sheldon S Rose P Flanagan ML Koshman S Killam (1996) ArticleTitleRisk factors for syncope recurrent after a positive tilt table test in patients with syncope. Circulation 93 973–981 Occurrence Handle1:STN:280:BymC2sbgt1w%3D Occurrence Handle8598089

    CAS  PubMed  Google Scholar 

Download references

Acknowledgements

This work was supported by Capital Medical Development Foundation of China Grant 2001-3037.

Author information

Authors and Affiliations

  1. Department of Pediatrics, The First Hospital, Peking University, Beijing 100034, Xi-An Men Street, No.1, Beijing 100034, P. R. China

    Z. Qingyou, D. Junbao, C. Jianjun & L. Wanzhen

Authors
  1. Z. Qingyou
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. D. Junbao
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. C. Jianjun
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. L. Wanzhen
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to D. Junbao.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Qingyou, Z., Junbao, D., Jianjun, C. et al. Association of Clinical Characteristics of Unexplained Syncope with the Outcome of Head-Up Tilt Tests in Children. Pediatr Cardiol 25, 360–364 (2004). https://doi.org/10.1007/s00246-003-0513-4

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00246-003-0513-4

Keywords

Search

Navigation