Abstract
Our environment is polluted with toxic compounds including polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and coplanar polychlorinated biphenyls (Co-PCBs). We investigated the suitability of hair analysis for testing human exposure to toxic compounds. Hair analysis revealed that municipal solid-waste (MSW) incineration workers were exposed to PCDDs, PCDFs, and Co-PCBs at high levels. The total 2,3,7,8-TCDD toxic equivalent concentration in MSW incineration workers was 2.5 times higher than in the general population, thus indicating that the indoor environment of the incineration facility was more polluted than the general environment. There were also characteristic patterns of occurrence of these dioxin-like compounds in the hair of smokers from the general population. We confirmed that hair analysis is useful for evaluating human exposure to PCDDs, PCDFs, and Co-PCBs in the atmosphere.
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K Ballschmiter R Niemczyk W Schäfer W Zoller (1987) ArticleTitleIsomer-specific identification of polychlorinated benzenes (PCBz) and biphenyls (PCB) in effluent of municipal waste incineration Anal Chem 328 583–587
A Covaci M Tutudaki AM Tsatsakis P Schepens (2002) ArticleTitleHair analysis: Another approach for the assessment of human exposure to selected persistent organochlorine pollutants Chemosphere 46 413–418
M Hiraoka Y Takizawa Y Masuda R Takeshita K Yagome M Tanaka et al. (1987) ArticleTitleInvestigation on generation of dioxins and related compounds from municipal incinerators in Japan Chemosphere 16 1901–1906
M Hiraoka S Sakai H Yoshida (1992) ArticleTitleJapan’s guidelines for controlling dioxins and dibenzofurans in municipal waste treatment Chemosphere 25 1393–1398
FW Karasek LC Dickson (1987) ArticleTitleModel studies of polychlorinated dibenzo-p-dioxin formation during municipal refuse incineration Science 237 754–756
RJ Kociba DG Keyes JE Beyer RM Carreon CE Wade DA Dittenber et al. (1978) ArticleTitleResults of a two-year chronic toxicity and oncogenicity study of 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats Toxicol Appl Pharmacol 46 279–303
EE McConnell JA Moore DW Dalgard (1978) ArticleTitleToxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in rhesus monkeys (Macaca mulatta) following a single oral dose Toxicol Appl Pharmacol 43 175–187
T Matsueda Y Kurokawa Y Osaki H Hirakawa T Iida (1992) ArticleTitleEffect of cigarette smoking on the concentration of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in indoor air J Environ Chem 2 791–799
H Miyata O Aozasa Y Mase S Ohta S Khono S Asada (1994) ArticleTitleEstimated annual emission of PCDDs, PCDFs and non-ortho chlorine-substituted coplanar PCBs from flue gas from urban waste incinerators in Japan Chemosphere 29 2097–2105
H Muto Y Takizawa (1989) ArticleTitleDioxins in cigarette smoke Arch Environ Health 44 171–174
T Nakao O Aozasa S Ohta H Miyata (2002) ArticleTitleAssessment of human exposure to PCDDs, PCDFs and Co-PCBs using hair as a human pollution indicator sample. I: Development of analytic method for human hair and evaluation for exposure assessment Chemosphere 48 885–896
K Neuber G Merkel FFE Randow (1999) ArticleTitleIndoor air pollution by lindane and DDT indicated by head hair samples of children Toxicol Lett 107 189–192
T Ohgami S Nonaka F Murayama K Yamashita H Irufune M Watanabe et al. (1991) ArticleTitleA comparative study on polychlorinated biphenyls (PCB) and polychlorinated quaterphenyls (PCQ) concentrations in subcutaneous fat tissue, blood and hair of patients with Yusho and normal control in Nagasaki Prefecture Fukuoka Igaku Zasshi 80 307–312
K Olie PL Vermeulen O Hutzinger (1977) ArticleTitleChlorodibenzo-p-dioxins and chlorodibenzofurans are trace compounds of fly ash and flue gas of some municipal incinerators in the Netherlands Chemosphere 6 455–459
A Poland A Kende (1976) ArticleTitle2,3,7,8-tetrachlorodibenzo-p-dioxin. Environmental contaminant and molecular probe Fed Proc 35 2404–2411
C Rappe M Nygren S Marklund LO Keller PA Bergqvist M Hansson (1985) ArticleTitleAssessment of human exposure to polychlorinated dibenzofurans and dioxins Environ Health Perspect 60 303–304
S Sakai M Hiraoka N Takeda K Shiozaki (1994) ArticleTitleFormation and emission of non-ortho CBs and mono-ortho CBs in municipal waste incineration Chemosphere 29 1979–1986
A Schecter JJ Ryan O Papke (1998) ArticleTitleDecrease in levels and body burden of dioxins, dibenzofurans, PCBs, DDE and HCB in blood and milk in a mother nursing twins over a thirty-eight month period Chemosphere 37 1807–1816
KW Schramm T Kuettner S Weber K Lutzke (1992) ArticleTitleDioxin hair analysis as monitoring pool Chemosphere 24 351–358
KW Schramm T Küttner S Weber A Kettrup (1993) ArticleTitlePCDD/DF in hair Organohal Compd 13 73–75
KW Schramm (1997) ArticleTitleHair: A matrix for non-invasive biomonitoring of organic chemicals in mammals Bull Environ Contam Toxicol 59 396–402
Berg ParticleVan den L Birnbaum A Bosveld B Brunström P Cook M Feeley et al. (1998) ArticleTitleToxic equivalency factors (TEFs) for PCBs, PCDDs, and PCDFs for humans and wildlife Environ Health Perspect 106 775–792
A Yasuhara M Morita (1989) ArticleTitleFormation of chlorodibenzofurans by thermal decomposition of vinilydene chloride polymer Chemosphere 18 1737–1740
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We gratefully acknowledge the research support provided by Grant-in Aid for Scientific Research (C) Grant No. 07670468.
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Nakao, T., Aozasa, O., Ohta, S. et al. Survey of Human Exposure to PCDDs, PCDFs, and Coplanar PCBs Using Hairas an Indicator. Arch Environ Contam Toxicol 49, 124–130 (2005). https://doi.org/10.1007/s00244-004-0059-3
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DOI: https://doi.org/10.1007/s00244-004-0059-3