Skip to main content
SpringerLink
Log in

The effects of shock waves on lung tissue in acute period: an in vivo study

  • Original Paper
  • Published:
Urological Research Aims and scope Submit manuscript

Abstract

The acute effects of extracorporeal shock waves on lung morphology were studied by light microscopy in 30 New Zealand rabbits. The left kidneys of the ten animals were exposed to 2,000 shockwaves at 18 kV under anesthesia (ESWL group). Ten rabbits were in the control group; an intramuscular anesthetic agent (ketamine) and intravenous contrast media were administered to ten animals in the sham group. Localization of the left kidneys was achieved following contrast medium injection through an ear vein under fluoroscopic control. The animals were killed after the ESWL procedures and the lungs were removed. Edema, emphysema, hemorrhage, congestion, inflammation, loss of normal structure, and epithelial desquamation were determined and graded between 0 and 3 in all areas of both lungs. In order to determine whether proximity has any effect on the histopathological changes, left and right lungs were evaluated separately as well as upper and lower lobes. We found that ESWL exposed to kidney also affects all areas of the lungs in a rabbit model.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

References

  1. Chaussy CH, Brendel W, Schmiedt E (1980) Extracorporeally induced destruction of kidney stones by shock waves. Lancet 2:1265–1268

    Article  PubMed  CAS  Google Scholar 

  2. Benyi L, Weizheng Z, Puyun L (1995) Protective effects of nifedipine and allopurinol on high energy shock wave induced acute changes of renal function. J Urol 153:596–598

    Article  Google Scholar 

  3. Karalezli G, Gogus O, Beduk Y, Kokuuslu C, Sarıca K, Kutsal O (1993) Histopathologic effects of extracorporeal shock wave lithotripsy on rabbit kidney. Urol Res 21:67–70

    Article  PubMed  CAS  Google Scholar 

  4. Kaji DM, Xie HW, Hardy BE, Sherrod A, Huffman JL (1991) The effects of extracorporeal shock wave lithotripsy on renal growth, function and arterial blood pressure in an animal model. J Urol 146:544–547

    PubMed  CAS  Google Scholar 

  5. Serel TA, Ozguner F, Soyupek S (2004) Prevention of shock wave-induced renal oxidative stress by melatonin: an experimental study. Urol Res 32:69–71

    Article  PubMed  CAS  Google Scholar 

  6. Weber C, Moram ME, Braun EJ, Drach GW (1991) Injury of rat renal vessels following extracorporeal shock wave treatment. J Urol 147:476–481

    Google Scholar 

  7. Ilnyckyj A, Hosking DH, Pettigrew NM, Bernstein CN (1999) Extra-corporeal shock wave lithotripsy causing colonic injury. Dig Dis Sci 44:2485–2487

    Article  PubMed  CAS  Google Scholar 

  8. Tiede JM, Lumpkin EN, Wass CT, Long TR (2003) Hemoptysis following extracorporeal shock wave lithotripsy: a case of lithotripsy-induced pulmonary contusion in a pediatric patient. J Clin Anesth 15:530–533

    Article  PubMed  Google Scholar 

  9. Malhotra V, Gomillion MC, Artusio JF (1989) Hemoptysis in a child during extracorporeal shock wave lithotripsy. Anesth Analg 69:526–528

    Article  PubMed  CAS  Google Scholar 

  10. Malhotra V, Rosen RJ, Slepian RL (1991) Life-threatening hypoxemia after lithotripsy in an adult due to shock-wave-induced pulmonary contusion. Anesthesiology 75:529–531

    Article  PubMed  CAS  Google Scholar 

  11. Hassan I, Zietlow SP (2002) Acute pancreatitis after extracorporeal shock wave lithotripsy for a renal calculus. Urology 60:1111–1113

    Article  PubMed  Google Scholar 

  12. Hung SY, Chen HM, Jan YY, Chen MF (2000) Common bile duct and pancreatic injury after extracorporeal shock wave lithotripsy for renal stone. Hepatogastroenterology 47:1162–1163

    PubMed  CAS  Google Scholar 

  13. Geh JL, Curley P, Mayfield MP, Price JJ (1997) Small bowel perforation after extracorporeal shock wave lithotripsy. Br J Urol 79:648–649

    PubMed  CAS  Google Scholar 

  14. Castillon I, Frievro O, Gonzales-Enguita C, Vela-Navarrete R (1999) Colonic perforation after extracorporeal shock wave lithotripsy. BJU Int 83:720–721

    Article  PubMed  CAS  Google Scholar 

  15. Gugulakis Ag, Matsagas MI, Liapis CD, Vasdekis SN, Sechas MN (1998) Rupture of the abdominal aorta following extracorporeal shock-wave lithotripsy. Eur J Surg 164:233–235

    Article  PubMed  Google Scholar 

  16. Bex A, Goepel M, Mollhoff S (1992) Extensive retroperitoneal hematoma following extracorporeal shock wave lithotripsy with second generation lithotripter. Urol Int 48:111–114

    Article  PubMed  CAS  Google Scholar 

  17. Newmark JR, Wong MYC and Lingeman JE (1996) Complications. In: Smith AD (ed) Smith’s Textbook of Endourology. Quality Medical Publishing, St. Louis, pp 681–693

  18. Shukla AR, Hoover DL, Homsy YL, Perlman S, Schurman S, Reisman EM (2001) Urolithiasis in the low birth weight infant: the role and the efficacy of extracorporeal shock wave lithotripsy. J Urol 165:2320–2323

    Article  PubMed  CAS  Google Scholar 

  19. Chaussy CG (1982) Extracorporeal shock wave lithotripsy: new aspects in the treatment of kidney stone disease. Karger, Munich, pp 24–35

  20. Delius M, Enders G, Heine G, Stark J, Remberger K, brendel W (1987) Biological effects of shock waves: lung hemorrhage by shock waves in dogs-pressure dependence. Ultrasound Med Biol 13:61–67

    Article  PubMed  CAS  Google Scholar 

  21. Chaussy C, Schmiedt E, Jocham D et al (1982) Extracorporeal shock wave lithotripsy. Karger, Basel, pp 1–112

    Google Scholar 

  22. Sigman M, Laudone VP, Jenkins AD, Howards SS, Riehle R Jr, Keating MA, Walker RD (1987) Initial experience with extracorporeal shock wave lithotripsy in children. J Urol 138:839–841

    PubMed  CAS  Google Scholar 

  23. Sturtevant B (1996) Shock wave physics of lithotripters. In: Smith AD, Badlani GH, Bagley DH et al eds) Smith’s textbook of endourology. Quality Medical Publishing, St Louis, pp 529–552

    Google Scholar 

  24. Berger JJ, Boysen PG, Gravenstein JS, Banner MJ, Carlson CA (1987) Failure of high frequency jet ventilation to ventilate patients adequately during extracorporeal shock-wave lithotripsy. Anesth Analg 66:262–263

    Article  PubMed  CAS  Google Scholar 

  25. Zeitling GL, Roth RA (1988) Effect of three anesthetic techniques on the success of extracorporeal shock wave lithotripsy in nephrolithiasis. Anesthesiology 68:272–276

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Urology, AIBU School of Medicine, Bolu, Turkey

    Muzaffer Eroglu

  2. Department of Urology, Fatih University School of Medicine, Ankara, Turkey

    Ersin Cimentepe

  3. Department of Pathology, SB Sanatoryum Hospital, Ankara, Turkey

    Funda Demirag

  4. Lung Disease, SB Sanatoryum Hospital, Ankara, Turkey

    Ebru Unsal

  5. Department of Urology, Kecioren Training and Research Hospital, Ankara, Turkey

    Ali Unsal

Authors
  1. Muzaffer Eroglu
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Ersin Cimentepe
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Funda Demirag
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Ebru Unsal
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Ali Unsal
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Muzaffer Eroglu.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Eroglu, M., Cimentepe, E., Demirag, F. et al. The effects of shock waves on lung tissue in acute period: an in vivo study. Urol Res 35, 155–160 (2007). https://doi.org/10.1007/s00240-007-0092-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00240-007-0092-6

Keywords

Search

Navigation