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Preoperative embolization of intracranial meningiomas using n-butyl cyanoacrylate

  • Interventional Neuroradiology
  • Published:
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Abstract

Introduction

Preoperative embolization for intracranial meningioma has been controversial for several decades. This study retrospectively reviewed our experience using n-butyl cyanoacrylate (n-BCA) to identify the factors for effective devascularization and procedure-related complications.

Methods

Fifty-seven patients who underwent preoperative embolization with n-BCA were analyzed to collect the following data: age, sex, tumor size, location, pathology, and presence or absence of pial arterial supply. The predictive factors for total devascularization and complications were examined using univariate and multivariate analyses.

Results

Injected n-BCA penetrated into the tumor vessels in 51 cases (89 %) but resulted in feeder occlusion in 6 (11 %). Angiographic total devascularization was achieved in 29 cases (51 %) and partial devascularization in 28 (49 %). Small size, superficial location, and absence of pial supply were independent factors for total devascularization. No major complication was encountered, but asymptomatic or transient adverse events occurred in nine patients and were significantly associated with elderly patients and large tumors.

Conclusion

Preoperative embolization for intracranial meningiomas using n-BCA can attain effective devascularization without major complications. The effect of preoperative embolization on surgical resection or patient outcome is still unknown.

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Ethical standards and patient consent

We declare that all human and animal studies have been approved by the Institutional Review Board of Gunma University Graduate School of Medicine and have therefore been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments. We declare that all patients gave informed consent prior to inclusion in this study.

Conflict of interest

We declare that we have no conflict of interest.

Author information

Authors and Affiliations

  1. Department of Neurosurgery, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma, 371-8511, Japan

    Masanori Aihara, Tatsuya Shimizu & Yuhei Yoshimoto

  2. Department of Neurosurgery, Geriatrics Research Institute and Hospital, Maebashi, Gunma, Japan

    Isao Naito & Naoko Miyamoto

  3. Department of Neurosurgery, Maebashi Red Cross Hospital, Maebashi, Gunma, Japan

    Hiroya Fujimaki & Ken Asakura

Authors
  1. Masanori Aihara
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  2. Isao Naito
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  3. Tatsuya Shimizu
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  4. Hiroya Fujimaki
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  5. Ken Asakura
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  6. Naoko Miyamoto
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  7. Yuhei Yoshimoto
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Corresponding author

Correspondence to Masanori Aihara.

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Aihara, M., Naito, I., Shimizu, T. et al. Preoperative embolization of intracranial meningiomas using n-butyl cyanoacrylate. Neuroradiology 57, 713–719 (2015). https://doi.org/10.1007/s00234-015-1521-9

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  • DOI: https://doi.org/10.1007/s00234-015-1521-9

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