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Safety of endovascular treatment of intracranial aneurysms with a new, complex shaped Guglielmi detachable coil

  • Interventional Neuroradiology
  • Published:
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Abstract

Introduction

The Guglielmi detachable coil (GDC) 360°, a new complex shaped bare platinum coil, became available in Europe for aneurysm treatment in September 2005. The purpose of this study was to assess the feasibility and safety of selective embolization of intracranial aneurysms with the GDC 360° in 52 consecutive patients.

Methods

All patients included in this study were registered in a prospectively maintained database. We assessed the patient clinical history, aneurysm shape and dimensions, technical details and complications of the procedures, degree of aneurysm occlusion, and clinical findings upon discharge. In all patients, the first coil deployed was a GDC 360°.

Results

Over a 6-month period, we intended to treat 52 aneurysms with the GDC 360° in 52 patients. Of these 52 patients, 42 (81%) were treated in the context of subarachnoid haemorrhage. In 51 of 52 patients, the underlying aneurysm was successfully treated by coil embolization. Six procedures (11.5%) were complicated by the formation of thrombus in the parent artery during the intervention. One patient suffered a stroke related to the procedure. Angiograms obtained immediately after the procedure showed complete occlusion of the aneurysmal sac in 38 of 51 procedures (74.5%), a neck remnant in 11 (21.6%), and a residual aneurysm in 2 (3.9%). In 43 of 51 patients (84.3%), clinical assessment demonstrated independent clinical status, whereas 7 patients (13.7%) required assistance in the activities of daily living upon hospital discharge. One patient (2.0%) died after development of a severe vasospasm 10 days after the endovascular procedure.

Conclusion

The GDC 360° can be safely used for the endovascular occlusion of intracranial aneurysms.

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Conflict of interest statement

We declare that we have no conflict of interest.

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Authors and Affiliations

  1. Department of Neuroradiology, Hôpital Roger Salengro, University Hospital Lille, Lille, France

    Christian A. Taschner, Xavier Leclerc, Jean-Yves Gauvrit, Anis Kerkeni, Mohamed El-Mahdy & Jean-Pierre Pruvo

  2. Department of Neurosurgery, Hôpital Roger Salengro, University Hospital Lille, Lille, France

    Jean-Paul Lejeune

  3. Service de Neuroradiologie, Hôpital Roger Salengro, C.H.R.U., Lille, Rue Emile Laine, 59037, Lille Cedex, France

    Christian A. Taschner

Authors
  1. Christian A. Taschner
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  2. Xavier Leclerc
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  3. Jean-Yves Gauvrit
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  4. Anis Kerkeni
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  5. Mohamed El-Mahdy
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  6. Jean-Paul Lejeune
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  7. Jean-Pierre Pruvo
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Correspondence to Christian A. Taschner.

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Taschner, C.A., Leclerc, X., Gauvrit, JY. et al. Safety of endovascular treatment of intracranial aneurysms with a new, complex shaped Guglielmi detachable coil. Neuroradiology 49, 761–766 (2007). https://doi.org/10.1007/s00234-007-0247-8

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  • DOI: https://doi.org/10.1007/s00234-007-0247-8

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