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Methanol poisoning: acute MR and CT findings in nine patients

  • Diagnostic Neuroradiology
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Abstract

Introduction

Methanol poisoning is an uncommon but potent central nervous system toxin. We describe here the CT and MR findings in nine patients following an outbreak of methanol poisoning.

Methods

Five patients with a typical clinical presentation and elevated anion and osmolar gaps underwent conventional brain MRI with a 1.5-T Gyroscan Interna scanner. In addition nonenhanced CT was performed in another three patients with more severe toxicity.

Results

Bilateral hemorrhagic or nonhemorrhagic necrosis of the putamina, diffuse white matter necrosis, and subarachnoid hemorrhage were among the radiological findings. Various patterns of enhancement of basal ganglial lesions were found including no enhancement, strong enhancement and rim enhancement.

Conclusion

A good knowledge of the radiological findings in methanol poisoning seems to be necessary for radiologists. The present study is unique in that it enables us to include in a single report most of the radiological findings that have been reported previously.

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Conflict of interest statement

We declare that we have no conflict of interest.

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Authors and Affiliations

  1. Department of Radiology, Shiraz University of Medical Sciences, Shiraz, Iran

    S. Sefidbakht, A. R. Rasekhi, K. Kamali, A. Meshksar & S. A. Nabavizadeh

  2. Department of Neurology, Shiraz University of Medical Sciences, Shiraz, Iran

    A. Borhani Haghighi

  3. Department of Ophthalmology, Shiraz University of Medical Sciences, Shiraz, Iran

    A. Salooti

  4. Department of Surgery, Shiraz University of Medical Sciences, Shiraz, Iran

    H. R. Abbasi

  5. Department of Internal Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

    M. Moghadami

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  1. S. Sefidbakht
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  2. A. R. Rasekhi
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  3. K. Kamali
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  4. A. Borhani Haghighi
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  9. S. A. Nabavizadeh
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Correspondence to S. A. Nabavizadeh.

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Sefidbakht, S., Rasekhi, A.R., Kamali, K. et al. Methanol poisoning: acute MR and CT findings in nine patients. Neuroradiology 49, 427–435 (2007). https://doi.org/10.1007/s00234-007-0210-8

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  • DOI: https://doi.org/10.1007/s00234-007-0210-8

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