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Interface management of pharmacotherapy. Joint hospital and primary care drug recommendations

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Abstract

Purpose

In September 2012 an interactive course on the “Interface Management of Pharmacotherapy” was organized by the Stockholm Drug and Therapeutics Committee in cooperation with Department of Clinical Pharmacology at Karolinska Institutet and at Karolinska University Hospital in Stockholm, Sweden, in collaboration with the WHO. The basis for the course was the “Stockholm model” for the rational use of medicines but also contained presentations about successful models in interface management of pharmacotherapy in other European countries.

Methods

The “Stockholm model” consists of 8 components: 1) Independent Drug and Therapeutics Committee with key role for respected drug experts with policy for “interest of conflicts”, 2) The “Wise List”, recommendations of medicines jointly for primary and hospital care, 3) Communication strategy with continuous medical education, 4) Systematic introduction of new expensive medicines, 5) E-pharmacological support at “point of care”, 6) Methods and tools for follow-up of medicines use, 7) Medicines policy strategy and 8) Operative resources.

Results

The course highlighted the importance of efficient and targeted communication of drug recommendations building on trust among prescribers and patients for the guidelines to achieve high adherence. Trust is achieved by independent Drug and Therapeutics Committees with a key role for respected experts and a strict policy for “conflicts of interest”. Representations of GPs are also crucial for successful implementation, being the link between evidence based medicine and practice.

Conclusion

The successful models in Scotland and in Stockholm as well as the ongoing work in Catalonia were considered as examples of multifaceted approaches to improve the quality of medicine use across primary and hospital care.

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References

  1. Diogene E, Figueras A (2011) What public policies have been more effective in promoting rational prescription of drugs? J Epidemiol Community Health 65(5):387–388

    Article  PubMed  Google Scholar 

  2. Laing R, Waning B, Gray A, Ford N (2003) E. t Hoen, 25 years of the WHO essential medicines lists: progress and challenges. Lancet 361(9370):1723–1729

    Article  PubMed  Google Scholar 

  3. Gustafsson LL, Wettermark B, Godman B, Andersen-Karlsson E, Bergman U, Hasselstrom J et al (2011) The ‘wise list’- a comprehensive concept to select, communicate and achieve adherence to recommendations of essential drugs in ambulatory care in Stockholm. Basic Clin Pharmacol Toxicol 108(4):224–233

    Article  PubMed  CAS  Google Scholar 

  4. Midlov P, Bergkvist A, Bondesson A, Eriksson T, Hoglund P (2005) Medication errors when transferring elderly patients between primary health care and hospital care. Pharm World Sci 27(2):116–120

    Article  PubMed  Google Scholar 

  5. Coma A, Zara C, Godman B, Agusti A, Diogene E, Wettermark B et al (2009) Policies to enhance the efficiency of prescribing in the Spanish Catalan region: impact and future direction. Expert Rev Pharmacoecon Outcomes Res 9(6):569–581

    Article  PubMed  Google Scholar 

  6. Dear J, O’Dowd C, Timoney A, Paterson KR, Walker A, Webb DJ (2007) Scottish Medicines Consortium: an overview of rapid new drug assessment in Scotland. Scott Med J 52(3):20–26

    Article  PubMed  CAS  Google Scholar 

  7. Laing R, Ruredzo R (1989) The essential drugs programme in Zimbabwe: new approaches to training. Health Policy Plan 4(3):229–234

    Article  Google Scholar 

  8. Laing R (1991) Essential drugs programmes in Africa. Afr Health 14(1):32–33

    PubMed  CAS  Google Scholar 

  9. Forløpsgruppe “Riktig legemiddelbruk (2009) Oslo, Norway. http://www.regjeringen.no/upload/HOD/Dokumenter%20SAM/Forl%C3%B8psrapporter/Forl%C3%B8psgruppe%206%20-%20Riktig%20legemiddelbruk.pdf Date of access: Feb 12th 2013

  10. En helhetlig integreringspolitikk. Mangfold og fellesskap (2012–2013) Melding til Stortinget: Oslo, Norway. http://www.regjeringen.no/nb/dep/hod/dok/regpubl/stmeld/2010-2011/meld-st-16-20102011/8/6.html?id=639843. Date of acess: Feb 12th 2013

  11. Spinewine A, Foulon V, Claeys C, Lepeleire JD, Chevalier P, Desplenter F (2010) Seamless care focusing on medication between hospital and home. Belgian Health Care Knowledge Centre (KCE), Brussels

    Google Scholar 

  12. Vogler S, Habl C, Leopold C, Mazag J, Morak S, Zimmermann N (2010) PHIS hospital pharma report. Pharmaceutical Health Information System (PHIS), Vienna

    Google Scholar 

  13. Grol R, Grimshaw J (2003) From best evidence to best practice: effective implementation of change in patients’ care. Lancet 362(9391):1225–1230

    Article  PubMed  Google Scholar 

  14. Sjöqvist F, Bergman U, Dahl ML, Gustafsson LL, Hensjö LO (2002) Drug and therapeutics committees: a Swedish experience. Drug Inf 12:207–213, WHO

    Google Scholar 

  15. Godman B,Gustafsson LL (2013) A new reimbursement system for innovative pharmaceuticals combining value-based and free market pricing. Correspondence. Appl Health Econ Health Policy 11:79–82

    Google Scholar 

  16. Persson U, Svensson J, Pettersson B (2012) A new reimbursement system for innovative pharmaceuticals combining value-based and free market pricing. Appl Health Econ Health Policy 10(4):217–225

    Article  PubMed  Google Scholar 

  17. Abernethy D, Birkett D, Brosen DK, Cascorbi I, Gustafsson LL, Hoppu K et al (2012) Clinical pharmacology in health care, teaching and research. Joint publication by WHO, CIOMS and IUPHAR (International Union of Pharmacology and Clinical Pharmacology). WHO, Geneva. Available at: http://www.cioms.ch/index.php/component/booklibrary/?task=view&Itemid=&id=46&catid=58

  18. Godman B, Paterson K, Malmstrom RE, Selke G, Fagot JP, Mrak J (2012) Improving the managed entry of new medicines: sharing experiences across Europe. Expert Rev Pharmacoecon Outcomes Res 12(4):439–441

    Article  PubMed  Google Scholar 

  19. Holmstrom M, Johnsson H, Larfars G, Malmstrom R, Hjemdahl P (2009) New drug in atrial fibrillation—how does it function in regular health care? Lakartidningen 106(45):3019–3020

    PubMed  Google Scholar 

  20. Covvey JR, McTaggart S, Bishop I (2010) Management of medication use in Scotland. Am J Health Syst Pharm 67(16):1378–1382

    Article  PubMed  Google Scholar 

  21. Bottiger Y, Laine K, Andersson ML, Korhonen T, Molin B, Ovesjo ML et al (2009) SFINX-a drug-drug interaction database designed for clinical decision support systems. Eur J Clin Pharmacol 65(6):627–633

    Article  PubMed  Google Scholar 

  22. Sjoborg B, Backstrom T, Arvidsson LB, Andersen-Karlsson E, Blomberg LB, Eiermann B et al (2007) Design and implementation of a point-of-care computerized system for drug therapy in Stockholm metropolitan health region–Bridging the gap between knowledge and practice. Int J Med Inform 76(7):497–506

    Article  PubMed  Google Scholar 

  23. Kotler P (2000) Marketing management, 10th edn. ed. New Jersey: Upper Saddle River

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Acknowledgments

This work was in part supported by grants from the Karolinska Institutet, Sweden. No writing assistance was provided for this paper.

Financial disclosure

There are no conflicts of interest reported by any of the authors. However, Eva Andersén-Karlsson is chairman of the DTC in Stockholm County Council.

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Correspondence to Linda Björkhem-Bergman.

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Björkhem-Bergman, L., Andersén-Karlsson, E., Laing, R. et al. Interface management of pharmacotherapy. Joint hospital and primary care drug recommendations. Eur J Clin Pharmacol 69 (Suppl 1), 73–78 (2013). https://doi.org/10.1007/s00228-013-1497-5

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  • DOI: https://doi.org/10.1007/s00228-013-1497-5

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