Skip to main content
Log in

Drug-use practices in teaching hospitals of Khartoum State, Sudan

  • Pharmacoepidemiology and Prescription
  • Published:
European Journal of Clinical Pharmacology Aims and scope Submit manuscript

Abstract

Purpose

The present study was carried out to investigate current prescribing and dispensing practices in the largest two teaching hospitals in Sudan and compare them with those of published studies in developing countries.

Methods

A descriptive, quantitative and cross-sectional study was conducted among hospital outpatients. The sample was selected using systematic random sampling. In each hospital, prescribing indicators were investigated through collection of data on 100 patient encounters, determination of consultation time and dispensing time for 100 patients, and by interview of 100 patients for the evaluation of dispensing practices.

Results

The present findings showed that 96% (95% CI: 92.0–98.1%) of patient encounters did not include one or more necessary elements. Strength of drug and the quantity to be dispensed were omitted in 57.5% (95% CI: 50.3–64.4%) and 91% (95% CI: 85.9–94.4%) of patient encounters, respectively. Other variables measured per patient encounter were mean (SD) number of drugs prescribed, 1.9 (0.9); percentage prescribed by generic name, 43.6 % (95% CI: 38.6–48.8%); percentage of patient encounters involving an antibiotic, 65.0% (95% CI: 57.9–71.5%); percentage of patient encounters with an injection prescribed, 10.5% (95% CI: 6.5–15.8%). The mean (SD) consultation and dispensing times were 4.5 (2.8) min and 46.3 (21.8) s, respectively. The percentages of dispensed drugs that were adequately labeled was 37.6% (95% CI: 33.1–41.8%), whilst adequate patient knowledge was demonstrated for 37.2% (95% CI: 32.3–42.0%) of drugs.

Conclusions

Cost-effective, multifaceted interventions are needed to improve current prescribing and dispensing practices at the teaching hospitals in Khartoum State, Sudan.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. World Health Organization (1985) The rational use of drugs. Report of conference of experts, Nairobi. World Health Organization, Geneva

    Google Scholar 

  2. Hogerzeil HV, Bimo, Ross-Degnan D, Laing RO, Ofori-Adjei D et al (1993) Field tests for rational drug use in twelve developing countries. Lancet 342:1408–1410

    Article  PubMed  CAS  Google Scholar 

  3. Quick JD, Hogerzeil HV, Velasquez G, Rago L (2002) Twenty-five years of essential medicines. Bull WHO 80 (11):913–914

    PubMed  Google Scholar 

  4. Bannenberg WJ, Forshaw CJ, Fresle D et al (1991) Evaluation of the Nile province essential drugs project, WHO/DAP/91.10. WHO, Geneva

    Google Scholar 

  5. Abdelmoneim IA, El-Tayeb IB, Omer ZB (1999) Investigation of drug use in health centers in Khartoum State. Sudan Med J 37:21–26

    Google Scholar 

  6. Eltayeb IB, Awad AI, Mohamed-Salih MS et al (2005) Changing the prescribing patterns of sexually transmitted infections in the White Nile region of Sudan. Sex Transm Infect 81(5):426–427

    Article  PubMed  CAS  Google Scholar 

  7. Awad AI, Eltayeb IB, Baraka OZ (2006) Changing antibiotics prescribing practices in health centers of Khartoum State, Sudan. Eur J Clin Pharmacol 3:1–8

    Google Scholar 

  8. Khalil Memon (2006) Use of drugs in Sind province, Pakistan, primary health care facilities. Available from http://dcc2.bumc.bu.edu/prdu/Other_Documents/Khalil_Concentration_Paper.htm. (Accessed 10 March 2006)

  9. Aurstiyono (2006) Promoting rational use of drugs at the community health centers in Indonesia. Available http://dcc2.bumc.bu.edu/prdu/Other_Documents/ARUS_INDONESIA_PRDU.htm. (Accessed 10 March 2006)

  10. World Health Organization (2002) Promoting rational use of medicines: core components. WHO Policy Perspectives on Medicines. WHO/EDM/2002.3. WHO, Geneva

    Google Scholar 

  11. World Health Organization (2000) WHO medicines strategy: framework for action in essential drugs and medicines policy 2000–2003. WHO/EDM/2000.1. WHO, Geneva

    Google Scholar 

  12. World Health Organization (1993) How to investigate drug use in health facilities: selected drug use indicators. WHO/DAP/ 93.1:1–87. WHO, Geneva

    Google Scholar 

  13. Isah AO, Ross-Degnan D, Quick J, Laing R, Mabadeje AFB (2006) The development of standard values for the WHO drug use prescribing indicators. International conference on improving use of medicines. Available from http://dcc2.bumc.bu.edu/prdu/ICIUM_Posters/1a2_txt.htm. (Accessed 10 March 2006)

  14. Hogerzeil HV (1995) Promoting rational prescribing: an international perspective. Br J Clin Pharmacol 39:1–6

    PubMed  CAS  Google Scholar 

  15. De Vries TP, Henning RH, Hogerzeil HV, Fresle DA (1994) Guide to good prescribing - a practical manual. WHO/DAP/94.11. WHO, Geneva

    Google Scholar 

  16. Tangwadzana A, Nhachi C (1999) An assessment of prescription writing and prescribing patterns among medical practitioners in the city of Harare, Zimbabwe. Honours Project Publications. Available from http://www.uz.ac.zw/medicine/pharmacy/pubs/19993.html

  17. World Health Organization (2001) Global strategy for containment of antimicrobial resistance. WHO Communicable Disease Surveillance and Response (CSR). WHO/CDS/CSR/DRS/2001.2. WHO, Geneva

    Google Scholar 

Download references

Acknowledgements

We owe a tremendous amount of gratitude to those who participated in the data collection; without their great efforts, this work would not have been achieved. We would like also to thank the local health authorities who gave us the permission to conduct this study. We gratefully acknowledge Dr. Phillips Capps for revising this manuscript.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Abdelmoneim Ismail Awad.

Additional information

Location: The data collection was conducted in Khartoum State, Sudan. Data analysis and manuscript writing were undertaken at the Faculty of Pharmacy, Kuwait University.

Funding: None.

Ethical Approval: General Directorate of Pharmacy-Ministry of Health, Sudan.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Awad, A.I., Himad, H.A. Drug-use practices in teaching hospitals of Khartoum State, Sudan. Eur J Clin Pharmacol 62, 1087–1093 (2006). https://doi.org/10.1007/s00228-006-0216-x

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00228-006-0216-x

Keywords

Navigation