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Relationship Between Nutritional Factors and Hip Bone Density in Individuals with Chronic Stroke

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Abstract

The aim of this study was to investigate the relationship between dietary habits and hip bone health in community-dwelling individuals with chronic stroke. The usual dietary intake of 94 individuals with chronic stroke (30 women, mean age: 59.0 years) was assessed by a 3-day food record within a single week. Dual-energy X-ray absorptiometry was used to measure bone mineral density (BMD) at both hips. The results showed that low hip bone mass was found in 59 and 50 of the participants on the affected and unaffected side, respectively. The mean hip BMD was also significantly lower on the affected side than the unaffected side (P < 0.001). The intake of total fat, carbohydrates, calcium, magnesium, iron, zinc, fiber, folic acid, vitamin B1, B2, B3, B6, C, and K was significantly lower than the respective recommended daily intake values (P < 0.05). Multiple regression analyses revealed that after adjusting for the effects of age, sex, body mass index, post-stroke duration, side of paresis, motor impairment, physical activity level, walking endurance, total calories intake, and total number of medications, intake of protein, fiber, and magnesium remained significantly associated with hip T score on the affected side, accounting for 4.2, 4.4, and 3.2% of the variance, respectively. On the other hand, intake of protein and fiber was independently associated with hip T score on the unaffected side, explaining 2.7 and 5.2% of the variance, respectively. The results highlighted the potential relevance of diet modification in maintaining bone health post stroke, which would require further study.

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Acknowledgements

This study was supported by a research grant provided by the Service Wellness Centre (Grant Number 8-ZD78).

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Authors and Affiliations

  1. Department of Rehabilitation Sciences, Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong

    Samuel K. Y. Li, Mabel M. P. Wan & Marco Y. C. Pang

  2. Sport Nutrition Monitoring Centre, Hong Kong Sports Institute, Sha Tin, Hong Kong

    Frankie P. L. Siu & Susan Chung

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  1. Samuel K. Y. Li
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  2. Mabel M. P. Wan
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  4. Susan Chung
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  5. Marco Y. C. Pang
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Contributions

S.K.Y.L contributed to statistical analysis of data, interpretation of data, and prepared the first draft of the paper. M.M.P.W designed the study and contributed to the acquisition of data, statistical analysis, and interpretation of data. F.P.L.S and S.C contributed to the acquisition of data, and interpretation of data. M.Y.C.P designed the study, interpretation of data, and was responsible for project management. He is guarantor. All authors revised the paper critically for intellectual content and approved the final version. All authors agree to be accountable for the work and to ensure that any questions relating to the accuracy and integrity of the paper are investigated and properly resolved.

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Correspondence to Marco Y. C. Pang.

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Human and Animal Rights

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Li, S.K.Y., Wan, M.M.P., Siu, F.P.L. et al. Relationship Between Nutritional Factors and Hip Bone Density in Individuals with Chronic Stroke. Calcif Tissue Int 101, 259–270 (2017). https://doi.org/10.1007/s00223-017-0276-1

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  • DOI: https://doi.org/10.1007/s00223-017-0276-1

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