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Anticipatory postural adjustment: the role of motor cortex in the natural and learned bimanual unloading

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Abstract

Anticipatory postural adjustment (APA) during bimanual action is observed when participants hold an object in one hand and then lift that object with the other hand. The decrease in activity of a forearm flexor muscle prior to an active forearm unloading acts to stabilize the forearm position. Recent studies have investigated the influence of the corticospinal system on muscle activity during APA through transcranial magnetic stimulation. It was shown that at different times during APA, the amplitude of motor-evoked potentials in the forearm flexors decreased in conjunction with the decrease of muscle activity. If the unloading is triggered via an electromagnet by lifting an equal weight by the other arm, the anticipatory postural adjustment is learned through the repetition of unloading (three series of 20 trials). Using the transcranial magnetic stimulation, we examined changes in the motor-evoked potential in the forearm flexors before and after APA learning. Motor-evoked potential amplitude did not significantly change as forearm flexor activity decreased. The motor-evoked potential/background electromyogram ratio, however, increased in the final learning session in comparison to the initial learning session and stationary loading. The present results corroborate a hypothesis on the fundamental role of the motor cortex in the suppression of synergies that interfere with the execution of the new coordination in the process of motor learning.

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References

  • Aruin AS, Latash ML (1995) Directional specificity of postural muscles in feed-forward postural reactions during fast voluntary arm movements. Exp Brain Res 103:323–332

    Article  PubMed  CAS  Google Scholar 

  • Aruin AS, Nicholas JJ, Latash ML (1997) Anticipatory postural adjustments during standing in below-the-knee amputees. Clin Biomech 12:52–59

    Article  Google Scholar 

  • Beloozerova IN, Sirota MG, Orlovsky GN, Deliagina TG (2005) Activity of pyramidal tract neurons in the cat during postural corrections. J Neurophysiol 93:1831–1844

    Article  PubMed  CAS  Google Scholar 

  • Carrol TJ, Riek S, Carson RG (2001) Corticospinal responses to motor training revealed by transcranial magnetic stimulation. Exerc Sport Sci Rev 29:54–59

    Article  Google Scholar 

  • Classen J, Liepert J, Wise SP, Hallett M, Cohen LG (1998) Rapid plasticity of human cortical movement representation induced by practice. J Neurophysiol 79:1117–1123

    PubMed  CAS  Google Scholar 

  • Davey NJ, Romaiguere P, Maskill DW, Ellaway PH (1994) Suppression of voluntary motor activity revealed using transcranial magnetic stimulation of the motor cortex in man. J Physiol 477:223–235

    PubMed  Google Scholar 

  • Deliagina TG, Orlovsky GN, Zelenin PV, Beloozerova IN (2006) Neural bases of postural control. J Physiol 21:216–25

    Article  Google Scholar 

  • Diedrichsen J, Verstynen T, Lehman SL, Ivry RB (2005) Cerebellar involvement in anticipating the consequences of self-produced actions during bimanual movement. J Neurophysiol 93:801–812

    Article  PubMed  Google Scholar 

  • Dufosse M, Hugon M, Massion J (1985) Postural forearm changes induced by predictable in time or voluntary triggered unloading in man. Exp Brain Res 60:330–334

    Article  PubMed  CAS  Google Scholar 

  • Horak F, Macpherson J (1996) Postural orientation and equilibrium. In: Handbook of physiology. Exercise: regulation and integration of multiple systems, sect 12, chap 7. American Physiological Society, Bethesda, pp 255–292

    Google Scholar 

  • Hugon M, Massion J, Wiesendanger M (1982) Anticipatory postural changes induced by active unloading and comparison with passive unloading in man. Pflugers Arch 393:292–296

    Article  PubMed  CAS  Google Scholar 

  • Ioffe M, Massion J, Gantchev N, Dufosse M, Kulikov MA (1996) Coordination between posture and movement in a bimanual load-lifting task: is there a transfer? Exp Brain Res 109:450–456

    Article  PubMed  CAS  Google Scholar 

  • Ioffe M, Massion J, Schmitz K, Viallet F, Gantcheva R (2002) Reorganization of motor patterns during motor learning a specific role of the motor cortex. In: Latash ML (ed) Progress in motor control-II. Human Kinetics, Champaign, pp 123–145

    Google Scholar 

  • Ioffe ME, Chernikova LA, Ustinova KI (2007) Role of cerebellum in learning postural tasks. Cerebellum 6:87–94

    Article  PubMed  CAS  Google Scholar 

  • Kang N, Shinohara M, Zatsiorsky, Latash ML (2004) Learning multi-finger synergies: an uncontrolled manifold analysis. Exp Brain Res 157:336–350

    Article  PubMed  Google Scholar 

  • Kawanishi M, Yahagi S, Kasai T (1999) Neural mechanisms of soleus H-reflex depression accompahying voluntary arm movement in standing humans. Brain Res 832:13–22

    Article  PubMed  CAS  Google Scholar 

  • Kazennikov O, Solopova I, Talis V, Grishin A, Ioffe M (2005) TMS-responses during anticipatory postural adjustment in bimanual unloading in humans. Neurosci Lett 383:246–250

    Article  PubMed  CAS  Google Scholar 

  • Kleim JA, Barbay S, Cooper NR, Hogg TM, Reidel CN, Remple MS, Nudo RJ (2002) Motor learning-dependent synaptogenesis is localized to functionally reorganized motor cortex. Neurobiol Learn Mem 77:63–77

    Article  PubMed  Google Scholar 

  • Liepert J (2006) Motor cortex excitability in stroke before and after constraint-induced movement therapy. Cogn Behav Neurol 19:41–47

    Article  PubMed  Google Scholar 

  • Liepert J, Classen J, Cohen LG, Hallett M (1998) Task-dependent changes of intracortical inhibition. Exp Brain Res 118:421–426

    Article  PubMed  CAS  Google Scholar 

  • Ljubisavljevic M (2006) Transcranial magnet stimulation and the motor learning-associated cortical plasticity. Exp Brain Res 173:215–22

    Article  PubMed  Google Scholar 

  • Massion J, Ioffe M, Schmitz C, Viallet F, Gantcheva R (1999) Acquisition of anticipatory postural adjustments in a bimanual load-lifting task: normal and pathological aspects. Exp Brain Res 128:229–235

    Article  PubMed  CAS  Google Scholar 

  • Monfils MH, Plautz EJ, Kleim JA (2005) In search of the motor engram: motor map plasticity as a mechanism for encoding motor experience. Neuroscientist 11:471–483

    Article  PubMed  Google Scholar 

  • Pascual-Leone A (2001) The brain that plays music and is changed by it Ann N Y Acad Sci 930:315–329

    Article  PubMed  CAS  Google Scholar 

  • Pascual-Leone A, Dang N, Cohen LG, Brasil-Neto JP, Cammarota A, Hallett M (1995) Modulation of muscle responses evoked by transcranial magnetic stimulation during the acquisition of new fine motor skills. J Neurophysiol 74:1037–1045

    PubMed  CAS  Google Scholar 

  • Paulignan Y, Dufosse M, Hugon M, Massion J (1989) Acquisition of co-ordination between posture and movement in a bimanual task. Exp Brain Res 77:337–348

    Article  PubMed  CAS  Google Scholar 

  • Romaiguere P, Calvin S, Roll J-P (2004) Transcranial magnetic stimulation of the sensorimotor cortex alters kinaesthesia. Neuroreport 16:693–697

    Article  Google Scholar 

  • Schmitz C, Assaiante C (2002) Developmental sequence in the acquisition of anticipation during a new co-ordination in a bimanual load-lifting task in children. Neurosci Lett 330:215–218

    Article  PubMed  CAS  Google Scholar 

  • Solopova IA, Kazennikov OV, Deniskina NB, Levik YS, Ivanenko YP (2003) Postural instability enhances motor responses to transcranial magnetic stimulation in humans. Neurosci Lett 337:25–28

    Article  PubMed  CAS  Google Scholar 

  • Sohn YH, Jung HY, Kaelin-Lang A, Hallet M (2003) Excitability of the ipsilateral motor cortex during voluntary hand movement. Exp Brain Res 148:176–185

    PubMed  Google Scholar 

  • Soto O, Valls-Solé J, Shanahan P, Rothwell J (2006) Reduction of intracortical inhibition in soleus muscle during postural activity. J Neurophysiol 96(4):1711–1717

    Article  PubMed  Google Scholar 

  • Tamarova ZA, Sirota MG, Orlovsky GN, Deliagina TG, Beloozerova IN (2007) Role of GABA A inhibition in modulation of pyramidal tract neuron activity during postural corrections. Eur J Neurosci 25(5):1484–1491

    Article  PubMed  Google Scholar 

  • Tyc F, Boyadian A (2006) Cortical plasticity and motor activity studied with transcranial magnetic stimulation. Rev Neurol 17:469–495

    Google Scholar 

  • Vialett F, Massion J, Massarino R, Khalil R (1992) Coordination between posture and movement in a bimanual load lifting task: putative role of a medial frontal region including the supplementary motor area. Exp Brain Res 88:674–684

    Google Scholar 

  • Zettel JL, McIlroy WE, Maki BE (2002) Can stabilizing features of rapid triggered stepping reactions be modulated to meet environmental constraints? Exp Brain Res 145:297–308

    Article  PubMed  Google Scholar 

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Acknowledgments

The authors thank Angela Antkowiak for reading and correcting the manuscript. The study was supported by the Russian Foundation of Basic Research (grants # 06-04-48891, 05-04-49401 and 05-04-48610), Russian Foundation of Humanity (grant 06-06-00275).

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Authors and Affiliations

  1. Laboratory of Neurobiology of Motor Control, Institute for Information Transmission Problems, Russian Academy of Science, Bolshoy Karetny 19, 127994, Moscow, Russia

    Oleg Kazennikov, Irina Solopova & Vera Talis

  2. Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Science, Butlerova 5a, 117485, Moscow, Russia

    Marat Ioffe

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  1. Oleg Kazennikov
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  2. Irina Solopova
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  3. Vera Talis
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  4. Marat Ioffe
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Correspondence to Marat Ioffe.

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Kazennikov, O., Solopova, I., Talis, V. et al. Anticipatory postural adjustment: the role of motor cortex in the natural and learned bimanual unloading. Exp Brain Res 186, 215–223 (2008). https://doi.org/10.1007/s00221-007-1224-5

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  • DOI: https://doi.org/10.1007/s00221-007-1224-5

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