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Three-dimensional graphene/amino-functionalized metal–organic framework for simultaneous electrochemical detection of Cd(II), Pb(II), Cu(II), and Hg(II)

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Abstract

Trace detection of multiple toxic heavy metals is a very important and difficult problem, conveniently, sensitively, and reliably. In this work, we developed an innovative electrochemical sensor for simultaneously detected heavy metal ions (Cd2+, Hg2+, Cu2+, and Pb2+). In order to detect trace amounts of Cd(II), Pb(II), Cu(II), and Hg(II) in food quickly, accurately, and at low cost, this study used electrochemical reduction to prepare a screen-printed electrode (3DGO) modified with 3DGO and UiO-66-NH2 composite nanomaterials (UiO-66-NH2/SPCE). The sensing platform is composed of three-dimensional graphene (3DGO), aminated UiO-66 metal–organic framework, named 3DGO/UiO-66-NH2. It is worth noting that the porous structure, amino functional groups on the surface, and large specific surface area of UiO-66-NH2 can enrich and promote the absorption of heavy metal ions. 3DGO was introduced to improve the electrochemical activity and conductivity of UiO-66-NH2 material. The construction of this new sensing platform, which can synchronously, reliably, and sensitively simultaneously detect Cd2+, Pb2+, Cu2+, and Hg2+ only in 150 s in the linear range of 0.01–0.35 pM with the detection limitations, is 10.90 fM, 5.98 fM, 2.89 fM, and 3.1 fM, respectively. This method provides a new strategy that uses MOF materials for electrochemical detection of a variety of heavy metal ions in food.

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Funding

This work was supported by the Open Project of State Key Laboratory of Urban Water Resources and Environment, Harbin Institute of Technology (Grant No. QAK202110), The National Key R&D Program of China (2017YFC1602000), Graduate Scientific Research and Innovation Foundation of Chongqing, China (CYB210739), Brew Microorganisms Technology and Application of Key Laboratory Project in Sichuan Province (No. NJ2020-03), Chongqing science and technology commission (CSTC2018jcyjAX0062), Chongqing Graduate Tutor Team Construction Project, and Analytical and Testing Center of Chongqing University for (SEM/TEM/XRD/HPLC-ICP-MS) the characterization of FT-IR and the sharing fund of Chongqing University’s large equipment.

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  1. Danqun Huo and Ya Zhang contributed equally to this work.

Authors and Affiliations

  1. Key Laboratory for Biorheological Science and Technology of Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, Sichuan, 400044, People’s Republic of China

    Danqun Huo, Ya Zhang, Ning Li, Wenhao Ma, Huan Liu, Zhihua Li & Mei Yang

  2. State Key Laboratory of Urban Water Resources & Environment, Harbin Institute of Technology, Harbin, Heilongjiang, 150090, People’s Republic of China

    Guoren Xu & Changjun Hou

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  1. Danqun Huo
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Correspondence to Changjun Hou.

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Huo, D., Zhang, Y., Li, N. et al. Three-dimensional graphene/amino-functionalized metal–organic framework for simultaneous electrochemical detection of Cd(II), Pb(II), Cu(II), and Hg(II). Anal Bioanal Chem 414, 1575–1586 (2022). https://doi.org/10.1007/s00216-021-03779-6

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