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Au/Ag composite-based SERS nanoprobe of Cr3+

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Abstract

Quantitative characterization of Cr3+, an important element revealing human metabolism and biological environmental variation, is still difficult to achieve by conventional biochemical methods due to the lack of high-sensitivity, real-time techniques with rapid response detection. Using surface-enhanced Raman scattering (SERS), we construct an Au/Ag composite-based SERS nanoprobe for the quantitative characterization of Cr3+ content in solution, in which DL-mercaptosuccinic acid (DL-MSA) is employed for Raman signal enhancement, and 4-mercaptobenzoic acid (4-MBA) is chosen as the Raman reporter. The achieved result demonstrates obvious advantages of the synthesized Au/Ag composite-based SERS nanoprobe in sensitivity and response speed. Importantly, this Au/Ag composite-based SERS nanoprobe might provide a new strategy for dynamic monitoring of Cr3+ content in human metabolism.

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Acknowledgments

This work is supported by the National Natural Science Foundation of China (grants: 61875059, 61727814 and 61575069).

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The authors declare that there are no conflicts of interest related to this article.

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Author notes

  1. Wendai Cheng and Ping Tang contributed equally to this work.

Authors and Affiliations

  1. Guangdong Provincial Key Laboratory of Nanophotonic Functional Materials and Devices, South China Normal University, Guangzhou, 510006, China

    Wendai Cheng, Ping Tang, Xuanmeng He, Xinyue Xing, Shengde Liu, Feng Zhang & Xiaoxu Lu

  2. Guangdong Provincial Key Laboratory of Photonics Information Technology, Guangdong University of Technology, Guangzhou, 510006, China

    Ping Tang & Liyun Zhong

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  1. Wendai Cheng
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Cheng, W., Tang, P., He, X. et al. Au/Ag composite-based SERS nanoprobe of Cr3+. Anal Bioanal Chem 413, 2951–2960 (2021). https://doi.org/10.1007/s00216-021-03228-4

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  • DOI: https://doi.org/10.1007/s00216-021-03228-4

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