Abstract
The identification of unknown non-volatile migrant compounds from adhesives used in food contact materials is a very challenging task because of the number of possible compounds involved, given that adhesives are complex mixtures of chemicals. The use of ultra-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry (UPLC-MS/QTOF) is shown to be a successful tool for identifying non-targeted migrant compounds from two hot melt adhesives used in food packaging laminates. Out of the seven migrants identified and quantified, five were amides and one was a compound classified in Class II of the Cramer toxicity. None of the migration values exceeded the recommended Cramer exposure values.
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P. Vera acknowledges a grant from the Gobierno de Aragón (Spain). The authors thank the suppliers of the market samples provided for this work. Thanks are given to Gobierno de Aragón (Spain) and Fondo Social Europeo for financing the Research Group GUIA, T-10.
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Vera, P., Canellas, E. & Nerín, C. Identification of non-volatile compounds and their migration from hot melt adhesives used in food packaging materials characterized by ultra-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry. Anal Bioanal Chem 405, 4747–4754 (2013). https://doi.org/10.1007/s00216-013-6881-6
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DOI: https://doi.org/10.1007/s00216-013-6881-6