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Host-molecule-coated quantum dots as fluorescent sensors

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Abstract

“Host” molecules, containing a binding site that is highly specific for an analyte “guest,” are used as sensors to register analyte binding through a variety of mechanisms such as colorimetric, fluorescent, or electrochemical signals. There is increasing interest in the host–guest chemistry on the surface of quantum dots (QDs) and in the changes that it produces in the luminescent properties of QDs. The bulk of this study focuses on those QDs with bound host molecules (crown ether, cyclodextrin, calixarene, and porphyrin) and the selectivity they display toward metal ions and small organic molecules.

Applications of host-molecule-coated quantum dots (QDs)

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Acknowledgements

We are grateful to the National Natural Science Foundation of China (20772038), the Program for Distinguish Young Scientist of Hubei Province (2007ABB017), the Program for Chenguang Young Scientist for Wuhan (200750731283), and the 863 program (2009AA06A417) for financial support of this work.

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  1. Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, 430079, China

    Cuiping Han & Haibing Li

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  1. Cuiping Han
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  2. Haibing Li
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Correspondence to Haibing Li.

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Han, C., Li, H. Host-molecule-coated quantum dots as fluorescent sensors. Anal Bioanal Chem 397, 1437–1444 (2010). https://doi.org/10.1007/s00216-009-3361-0

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