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SERS: a versatile tool in chemical and biochemical diagnostics

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Abstract

Raman spectroscopy is a valuable tool in various research fields. The technique yields structural information from all kind of samples often without the need for extensive sample preparation. Since the Raman signals are inherently weak and therefore do not allow one to investigate substances in low concentrations, one possible approach is surface-enhanced (resonance) Raman spectroscopy. Here, rough coin metal surfaces enhance the Raman signal by a factor of 104–1015, depending on the applied method. In this review we discuss recent developments in SERS spectroscopy and their impact on different research fields.

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Acknowledgement

We gratefully thank the “Fonds der Chemischen Industrie” for financial support.

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Authors and Affiliations

  1. Institut für Physikalische Chemie, Friedrich-Schiller-Universität Jena, Helmholtzweg 4, 07743, Jena, Germany

    Katharina Hering, Dana Cialla, Katrin Ackermann, Thomas Dörfer, Robert Möller, Petra Rösch & Jürgen Popp

  2. Institut für Photonische Technologien, Albert-Einstein-Str. 9, 07745, Jena, Germany

    Henrik Schneidewind, Roland Mattheis, Wolfgang Fritzsche & Jürgen Popp

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  1. Katharina Hering
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Hering, K., Cialla, D., Ackermann, K. et al. SERS: a versatile tool in chemical and biochemical diagnostics. Anal Bioanal Chem 390, 113–124 (2008). https://doi.org/10.1007/s00216-007-1667-3

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