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Micellar solid-phase microextraction for determining partition coefficients of substituted polycyclic aromatic hydrocarbons in micellar media: possible prediction of hydrocarbon–micelle behaviour

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Abstract

Micellar solid-phase microextraction (MSPME) coupled to gas chromatography-mass spectrometry (GC-MS) has been used to obtain partition coefficients of a group of 18 substituted aromatic hydrocarbons to ionic and nonionic micelles. Statistical and factor analyses have been utilized to establish some general equations relating molecular descriptors of non-substituted polycyclic aromatic hydrocarbons and their partition coefficients obtained by MSPME. The obtained equations have correlation coefficients higher than 0.94. They are used to predict hydrocarbon–micelle partition coefficients for a group of hydrocarbons with reported literature values giving a correlation coefficient of 0.98 and a standard deviation of the prediction of 0.182. The predictive model was also applied to substituted polycyclic aromatic hydrocarbons with partition coefficient values obtained by MSPME, with a 69% level of success.

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References

  1. Arthur CL, Pawliszyn J (1990) Anal Chem 62:2145–2148

    Article  CAS  Google Scholar 

  2. Arthur CL, Killam LM, Bucholz KD, Pawliszyn J, Berg JR (1992) Anal Chem 64:1960–1966

    Article  CAS  Google Scholar 

  3. Wang Y, O’Reilly J, Chen Y, Pawliszyn J (2005) J Chromatogr A 1072:13–17

    Article  CAS  Google Scholar 

  4. Pörschmann J, Zhang Z, Kopinke FD, Pawliszyn J (1997) Anal Chem 69:597–600

    Article  Google Scholar 

  5. Yuan H, Pawliszyn J (2001) Anal Chem 73:4410–4416

    Article  CAS  Google Scholar 

  6. Van Stempvoort DR, Lesage S (2002) Adv Environ Res 6:495–504

    Article  Google Scholar 

  7. Pacifici GM, Viani A (1992) Clin Pharmacokinet 23:449–468

    Article  CAS  Google Scholar 

  8. Jepson GW, Hoover DK, Black RK, McCafferty JD, Mahle DA, Gearhart JM (1994) Fundam Appl Toxicol 22:519–524

    Article  CAS  Google Scholar 

  9. Pino V, Ayala JH, González V, Afonso AM (2004) Anal Chem 76:4572–4578

    Article  CAS  Google Scholar 

  10. Pino V, Conde FJ, Ayala JH, Afonso AM, González V (2005) J Chromatogr A 1099:64–74

    Article  CAS  Google Scholar 

  11. Fendler JH (1984) Annu Rev Phys Chem 35:137–157

    Article  CAS  Google Scholar 

  12. Khaledi MG, Breyer ED (1989) Anal Chem 61:1040–1047

    Article  CAS  Google Scholar 

  13. Breyer ED, Strasters JK, Khaledi KG (1991) Anal Chem 63:828–833

    Article  CAS  Google Scholar 

  14. Abraham MH, Chadha HS, Dixon JP, Rafols C (1995) J Chem Soc-Perkin Trans 2(5):887–894

    Article  Google Scholar 

  15. Shahmirani S, Vasheghani-Farahani E, Ghasemi J (2006) Ann Chim 96:327–337

    Article  CAS  Google Scholar 

  16. Pino V, Conde FJ, Ayala JH, González V, Afonso AM (2006) Chromatographia 63:167–174

    Article  CAS  Google Scholar 

  17. Kier LB, Hall LH (1986) Molecular connectivity in structure-activity analysis. Research Studies Press, Hertfordshire, England and John Wiley and Sons, New York

  18. Mackay D, Shiu WY, Ma KC (1992) Illustrated handbook of physical-chemical properties and environmental fate of organic chemicals. V.2.: polynuclear aromatic hydrocarbons, polychlorinated dioxins, and dibenzofurans. Lewis, Chelsea, MI

    Google Scholar 

  19. Lyman WJ, Reehl WF, Rosenblatt DH (1996) Handbook of chemical property estimation methods: environmental behaviours of organic compounds. McGraw-Hill, Washington DC, Chapt 1

    Google Scholar 

  20. Dean JR, Tomlinson WR, Makovskaya V, Cumming R, Hetheridge M, Comber M (1996) Anal Chem 68:130–133

    Article  CAS  Google Scholar 

  21. Herbert BH, Dorsey JG (1995) Anal Chem 67:744–749

    Article  CAS  Google Scholar 

  22. Polo M, Casas V, Llompart M, García-Jares C, Cela R (2006) J Chromatogr A 1124:121–129

    Article  CAS  Google Scholar 

  23. Poole SK, Poole CF (2003) J Chromatogr B 797:3–19

    Article  CAS  Google Scholar 

  24. Berthod A, García-Álvarez-Coque C (2000) Micellar liquid chromatography. Marcel Dekker, New York, Appendix II

    Google Scholar 

  25. Tosato ML, Piazza R, Chiorboli C, Passerini L, Pino A, Cruciani G, Clementi S (1992) Chemiomet Intell Lab Syst 16:155–167

    Article  CAS  Google Scholar 

  26. Doong RA, Chang SM, Sun YC (2000) J Chromatogr A 879:177–188

    Article  CAS  Google Scholar 

  27. Pino V, Ayala JH, Afonso AM, González V (2003) Anal Chim Acta 477:81–91

    Article  CAS  Google Scholar 

Download references

Acknowledgements

Verónica Pino would like to thank the Spanish Ministry of Education and Science (Spain) the “Juan de la Cierva” contract with the University of La Laguna.

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Authors and Affiliations

  1. Department of Analytical Chemistry, Nutrition and Food Science, University of La Laguna, Campus de Anchieta, Astrofísico Francisco Sánchez s/n, 38205, La Laguna, Spain

    Verónica Pino, Ana M. Afonso, Juan H. Ayala & Venerando González

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  1. Verónica Pino
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  2. Ana M. Afonso
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  3. Juan H. Ayala
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  4. Venerando González
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Correspondence to Verónica Pino.

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Pino, V., Afonso, A.M., Ayala, J.H. et al. Micellar solid-phase microextraction for determining partition coefficients of substituted polycyclic aromatic hydrocarbons in micellar media: possible prediction of hydrocarbon–micelle behaviour. Anal Bioanal Chem 387, 2271–2281 (2007). https://doi.org/10.1007/s00216-006-1029-6

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  • DOI: https://doi.org/10.1007/s00216-006-1029-6

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