Abstract
A method based on matrix solid-phase dispersion (MSPD) and liquid chromatography–electrospay ionization–mass spectrometry used to analyze fifteen fungicide residues in fruits and vegetables is described. The method required only 0.5 g of sample, C18-bonded silica was used as dispersant sorbent, and ethyl acetate was used as eluting solvent. Fortified recoveries in apple, orange, banana, lettuce, grape and tomato samples ranged from 71% to 102% and relative standard deviations were less than 13% with fortified levels of 0.03–1.5 mg kg−1. Detection and quantification limits were 1~30 μg kg−1 and 4~100 μg kg−1, respectively, with linear calibration curves extending up to 15 mg kg−1. The analytical characteristics of MSPD compared very favorably with those found for a classical multiresidue method: the quick, easy, cheap, effective, rugged, and safe (QuEChERS) method. The method was applied to determine the fungicides in real samples. Liquid chromatography–tandem mass spectrometry (LC–MS–MS) was used as confirmatory tool for positive samples.
Similar content being viewed by others
References
Bright FV, McNally MEP (1992) Supercritical fluid technology: theroretical and applied approaches to analytical chemistry (ACS Symp Ser 488). American Chemical Society, Washington, DC
Ortelli D, Eedder P, Corvi C (2005) Food Addit Contam 22(5):423–428
Attilio V, Givanni V, Swizly SA, Francesco SA, Luca RDS (2004) Food Chem 87(3):383–3865
Torres CM, Picó Y, Maries J (1996) J Chromatogr A 754:301–331
Blasco C, Font G, Picó Y (2006) Food Control 17:841–846
Zamora T, Pozo OJ, López FJ, Hernández F (2004) J Chromatogr A 1045:137–143
Fernandez M, Rodríguez R, Picó Y, Manes J (2001) J Chromatogr A 912:301–310
Rodríguez R, Picó Y, Font G, Manes J (2002) J Chromatogr A 949:359–366
Rodríguez R, Picó Y, Font G, Manes J (2002) J Chromatogr A 924:387–396
Rodríguez R, Picó Y, Font G (2002) J Chromatogr A 949:359–366
Hu RW, Hennion B, Urruty L, Montury M (1999) Food Addit Contam 16:111–116
Navarro M, Picó Y, Marin R, Manes J (2002) J Chromatog A 968:201–209
Blasco C, Picó Y, Font G, Manes J (2002) J Chromatogr A 984:227–235
Barker SA (2000) J Chromatogr A 880:2443–2448
Fernandez M, Picó Y, Manes J (2000) J Chromatogr A 871:43–49
Blasco C, Picó Y, Manes J, Font G (2002) J Chromatogr A 947:227–234
Naoki Y, Yumi A, Kiyoshi T (2004) J Chromatogr A 1022:145–150
Reemtsma T (2001) Trends Anal Chem 20:500–505
Lacassie EM, Dreyfuss F, Daguet JL, Vignaud M, Marquet P, Lachatre G (1999) J Chromatogr A 830:135–141
Soler C, Manes J, Picó Y (2004) J Chromatogr A 1048:41–49
Aguera A, Lopez S, Fernandez-Alba AR, Contreras M, Crespo J, Piedra L (2004) J Chromatogr A 1045:125–132
Hetherton CL, Sykes MD, Fusell RJ, Goodall DM (2004) Rapid Commun Mass Spectrom 18:2443–2449
Rodríguez R, Picó Y, Font G, Manes J (2001) J Chromatogr A 924:387–396
Navarro M, Picó Y, Marin R, Manes J (2003) J Chromatogr A 908:201–209
Steven JL, Andrede K, Maurice H, Petervan B (2005) J AOAC Int 88:595–629
Dicorcia A, Creszenci C, Lagana A, Sebastiani E (1996) J Agric Food Chem 44:1930–1936
Trosken ER, Bittner N, Volker W (2005) J Chromatogr A 1083:113–119
Mallat E, Barcelo D, Tauler R (1997) Chromatographia 46:342–349
Fernandez M, Rodríguez R, Picó Y, Manes J (2001) J Chromatogr A 912:301–310
Lacassie E, Dreyfuss MF, Daguet JL, Vignaud M, Marquet P, Lachatre G (1999) J Chromatogr A 830:135–144
Steven J, Lehotay KM, Seon J (2005) J AOAC Int 88(2):630–638
Kristenson EM, Ramos L, Brinkman UAT (2006) Trends Anal Chem 25:96–111
Klein J, Alder L (2003) J AOAC Int 86:1015–1021
Zrostlikova J, Hajslova J, Kovalczuk T, Stipan R, Poustka J (2003) J AOAC Int 86:612–620
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Wang, S., Xu, Y., Pan, C. et al. Application of matrix solid-phase dispersion and liquid chromatography–mass spectrometry to fungicide residue analysis in fruits and vegetables. Anal Bioanal Chem 387, 673–685 (2007). https://doi.org/10.1007/s00216-006-0891-6
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00216-006-0891-6