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Determination of non-steroidal anti-inflammatory drugs in environmental samples by chromatographic and electrophoretic techniques

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Abstract

Non-steroidal anti-inflammatory drugs (NSAIDs) are a group of pharmaceutical compounds widely used in human health care and often found in the aquatic environment, with their metabolites. After an introduction that describes the general problem of drug contamination, the properties of NSAIDs, and environmental risk assessment, this review surveys the chromatographic and electrophoretic methods of analysis in use today for monitoring the most important representatives of this pharmaceutical class in different environmental samples.

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Notes

  1. EC50, median effective concentration

  2. LC50, lethal dose

  3. NOEC, lowest no-observed-effect concentration

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Authors and Affiliations

  1. Dipartimento di Chimica, Università “La Sapienza” di Roma, Piazzale Aldo Moro 5, P.O. Box 34, Posta 62, 00185, Roma, Italy

    Alessandra Gentili

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  1. Alessandra Gentili
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Correspondence to Alessandra Gentili.

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Gentili, A. Determination of non-steroidal anti-inflammatory drugs in environmental samples by chromatographic and electrophoretic techniques. Anal Bioanal Chem 387, 1185–1202 (2007). https://doi.org/10.1007/s00216-006-0821-7

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  • DOI: https://doi.org/10.1007/s00216-006-0821-7

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