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Microquantitative determination of hesperidin by pulse perturbation of the oscillatory reaction system

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Abstract

A simple and reliable kinetic method for the determination of hesperidin (Hesp) is developed. It is based on potentiometric monitoring of the concentration perturbations of the matrix reaction system which is in a stable non-equilibrium stationary state close to the bifurcation point. The Bray–Liebhafsky oscillatory reaction is used as the matrix system. The response of the matrix to perturbations by different concentrations of Hesp is followed by using a Pt electrode. A linear relationship between maximal potential shift and the logarithm of Hesp concentrations is obtained between 7.5 and 599.4 μg mL−1. The limit of detection is 0.65 μg mL−1. The described procedure has been successfully applied to the determination of Hesp from different sources (capsules, industrial and hand-squeezed orange juice, and white wine).

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Acknowledgements

The investigations were partially supported by The Ministry of Sciences and Environmental Protection Technologies and Development of Serbia, under the Project 1448.

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Authors and Affiliations

  1. Faculty of Pharmacy, University of Belgrade, Vojvode Stepe 450, 11000, Belgrade, Serbia and Montenegro

    Nataša Pejić & Slavica Blagojević

  2. Faculty of Physical Chemistry, University of Belgrade, Studentski trg 12–16, P.O. Box 137, 11001, Belgrade, Serbia and Montenegro

    Slobodan Anić, Vladana Vukojević & Ljiljana Kolar-Anić

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  1. Nataša Pejić
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  2. Slavica Blagojević
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  3. Slobodan Anić
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  4. Vladana Vukojević
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  5. Ljiljana Kolar-Anić
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Correspondence to Nataša Pejić.

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Pejić, N., Blagojević, S., Anić, S. et al. Microquantitative determination of hesperidin by pulse perturbation of the oscillatory reaction system. Anal Bioanal Chem 381, 775–780 (2005). https://doi.org/10.1007/s00216-004-2913-6

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  • DOI: https://doi.org/10.1007/s00216-004-2913-6

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