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LC-MS/MS method for the confirmatory determination of aromatic amines and its application in textile analysis

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Abstract

A confirmation method for the determination of 18 aromatic amines originating from azo dyes after reductive cleavage was developed. The method is based on the use of high-performance liquid chromatography/tandem mass spectrometry with atmospheric-pressure chemical ionization. For the identification of the analytes one precursor ion and two daughter ions (multi-reaction monitoring, MRM) were selected and the LC-MS/MS parameters optimized to obtain high sensitivity and selectivity. The linear ranges varied from 0.1–1 to 30–50 μg mL−1 with correlation coefficients of 0.99 or better. The applicability of the method to determine o-tolidine (3,3′-dimethylbenzidine) and 3,3′-dimethoxybenzidine in textiles following reductive cleavage of acid red 114, trypan blue, and Chicago sky blue 6B was demonstrated.

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Acknowledgements

The financial support from the Postgraduate Education and Research Program in Chemistry (PERCH), Royal Golden Jubilee Program and from the Alexander von Humboldt Stiftung are gratefully acknowledged.

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Authors and Affiliations

  1. Postgraduate Education and Research Program in Analytical Chemistry, Faculty of Science, Kasetsart University, Jatujak, Bangkok, 10900, Thailand

    P. Sutthivaiyakit, T. Aungpradit, R. Chanwirat & S. Chumanee

  2. GSF-Research Center for Environmental and Health, Institute of Ecological Chemistry, Ingolstaedter Landstrasse 1, 85758, Oberschleissheim, Germany

    S. Achatz, J. Lintelmann & A. Kettrup

Authors
  1. P. Sutthivaiyakit
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  2. S. Achatz
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  3. J. Lintelmann
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  4. T. Aungpradit
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  5. R. Chanwirat
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  6. S. Chumanee
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  7. A. Kettrup
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Correspondence to P. Sutthivaiyakit.

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Sutthivaiyakit, P., Achatz, S., Lintelmann, J. et al. LC-MS/MS method for the confirmatory determination of aromatic amines and its application in textile analysis. Anal Bioanal Chem 381, 268–276 (2005). https://doi.org/10.1007/s00216-004-2852-2

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  • DOI: https://doi.org/10.1007/s00216-004-2852-2

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