Skip to main content
Log in

Standing waves in the FitzHugh-Nagumo system and a problem in combinatorial geometry

  • Published:
Mathematische Zeitschrift Aims and scope Submit manuscript

Abstract

We show that there is a close relation between standing-wave solutions for the FitzHugh-Nagumo system

where 0<a<1/2 and δ γ=β 2 ∈ (0,a), and the following combinatorial problem:

(*) Given K points Q 1 , . . . , Q K R N with minimum distance 1, find out the maximum number of times that the minimum distance 1 can occur.

More precisely, we show that for any given positive integer K, there is a δ K >0 such that for 0<δ<δ K , there exists a standing-wave solution (u δ ,ν δ ) to the FitzHugh-Nagumo system with the property that u δ has K spikes Q δ 1,. . .,Q δ K and approaches an optimal configuration in (*), where .

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Alikakos, N., Fusco, G., Kowalczyk, M.: Finite dimensional dynamics and interfaces intersecting the boundary I. Indiana Univ. Math. J. 45, 1119–1155 (1996)

    Article  MATH  MathSciNet  Google Scholar 

  2. Alikakos, N., Kowalczyk, M.: Critical points of a singular perturbation problem via reduced energy and local linking. J. Diff. Eqs. 159, 403–426 (1999)

    Article  MATH  MathSciNet  Google Scholar 

  3. Bates, P., Dancer, E.N., Shi, J.: Multi-spike stationary solutions of the Cahn-Hilliard equation in higher-dimension and instability. Adv. Diff. Eqs. 4, 1–69 (1999)

    MATH  MathSciNet  Google Scholar 

  4. Bates, P., Fusco, G.: Equilibria with many nuclei for the Cahn-Hilliard equation. J. Diff. Eqs. 160, 283–356 (2000)

    Article  MATH  MathSciNet  Google Scholar 

  5. Bates, P., Shi, J.: Existence and instability of spike layer solutions to singular perturbation problems. J. Funct. Anal. 196, 211–264 (2002)

    Article  MATH  MathSciNet  Google Scholar 

  6. Bender, C.: Bestimmung der größten Zahl gleich großer Kugeln, welche sich auf eine Kugel von demselben Radius wie die übrigen auflegen lassen. Grunert Arch. 56, 302–313 (1874)

    MATH  Google Scholar 

  7. Chen, X., del Pino, M., Kowalczyk, M.: The Gierer and Meinhardt system: the breaking of homoclinics and multi-bump ground states. Commun. Contemp. Math. 3, 419–439 (2001)

    Article  MATH  MathSciNet  Google Scholar 

  8. Clement, P., Sweers, G.: Existence and multiplicity results for a semilinear eigenvalue problem. Ann. Scuola Norm. Sup. Pisa 14, 97–121 (1987)

    MATH  MathSciNet  Google Scholar 

  9. Conway, J.H., Sloan, N.J.A.: Sphere packings, lattices and groups, 3rd ed. Die Grundlehren der mathematischen Wissenschaften in Einzeldarstellungen 290, Springer, New York, Heidelberg, 1999

  10. Coxeter, H.S.M.: An upper bound for the number of equal nonoverlapping spheres that can touch another of the same size. Convexity, Proc. Symp. Pure Math. 7, 53–71 (1963)

    MATH  MathSciNet  Google Scholar 

  11. Dancer, E.N.: A note on the asymptotic uniqueness for some nonlinearities which change sign. Bull. Austral. Math. Soc. 61, 305–312 (2000)

    Article  MATH  MathSciNet  Google Scholar 

  12. Doelman, A., Kaper, T.J., van der Ploeg, H.: Spatially periodic and aperiodic multi-pulse patterns in the one-dimensional Gierer-Meinhardt equation. Methods Appl. Anal. 8, 387–414 (2001)

    MATH  MathSciNet  Google Scholar 

  13. Dancer, E.N., Yan, S.: Multipeak solutions for a singular perturbed Neumann problem. Pacific J. Math. 189, 241-262 (1999)

    MATH  MathSciNet  Google Scholar 

  14. Dancer, E.N., Yan, S.: Interior and boundary peak solutions for a mixed boundary value problem. Indiana Univ. Math. J. 48, 1177–1212 (1999)

    Article  MATH  MathSciNet  Google Scholar 

  15. Dancer, E.N., Yan, S.: A minimization problem associated with elliptic systems of FitzHugh-Nagumo type. Ann. Inst. H. Poincaré Anal. Non Linéaire 21, 237–253 (2004)

    Article  MATH  MathSciNet  Google Scholar 

  16. deFigueiredo, D.G., Mitidieri, E.: A Maximum Principle for an elliptic system and applications to semilinear problems. SIAM J. Math. Anal. 17, 836–849 (1986)

    Article  MathSciNet  Google Scholar 

  17. del Pino, M., Kowalczyk, M., Wei, J.: Multi-bump ground states for the Gierer-Meinhardt system in R 2. Ann. Inst. H. Poincaré Anal. Non Linéaire 20, 53–85 (2003)

    Article  MATH  Google Scholar 

  18. Fejes-Toth, L.: New results in the theory of packing and covering. In: Gruber, P.M., Wills, J.M. (eds.) Convexity and its Applications. Birkhäuser, Basel, 1983, pp. 318–359

  19. FitzHugh, R.: Impulse and physiological states in models of nerve membrans. Biophysics J. 1, 445–466 (1961)

    Article  Google Scholar 

  20. Floer, A., Weinstein, A.: Nonspreading wave packets for the cubic Schrödinger equation with a bounded potential. J. Funct. Anal. 69, 397–408 (1986)

    Article  MATH  MathSciNet  Google Scholar 

  21. Gui, C, Wei, J.: Multiple interior peak solutions for some singular perturbation problems. J. Diff. Eqs. 158, 1–27 (1999)

    Article  MATH  MathSciNet  Google Scholar 

  22. Gui, C., Wei, J.: On multiple mixed interior and boundary peak solutions for some singularly perturbed Neumann problems. Canad. J. Math. 52, 522–538 (2000)

    MATH  MathSciNet  Google Scholar 

  23. Gui, C., Wei, J., Winter, M.: Multiple boundary peak solutions for some singularly perturbed Neumann problems. Ann. Inst. H. Poincaré Anal. Non Linéaire 17, 47–82 (2000)

    Article  MATH  MathSciNet  Google Scholar 

  24. Erdös, P., Purdy, G.: Extremal problems in combinatorial geometry. In: Graham, R., Grötschel, M., Lovász, L. (eds.) Handbook of Combinatorics. Elsevier Science, B.V., 1995, pp. 809–871

  25. Harborth, H.: Solution to problem 664a. Elemente Math. 29, 14–15 (1974)

    MathSciNet  Google Scholar 

  26. Hodgkin, A.L., Huxley, A.F.: A quantitative description of membrane current and its application to conduction and excitation in nerve. J. Physiol. 117, 500–544 (1952)

    Google Scholar 

  27. Klaasen, G.A., Mitidieri, E.: Standing wave solutions for a system derived from the FitzHugh-Nagumo equations for nerve conduction. SIAM J. Math. Anal. 17, 74–83 (1986)

    Article  MATH  MathSciNet  Google Scholar 

  28. Klaasen, G.A., Mitidieri, E.: Standing wave solutions of a system of reaction-diffusion equations derived from the FitzHugh-Nagumo equations. SIAM J. Appl. Math. 44, 74–83 (1986)

    Google Scholar 

  29. Kowalczyk, M.: Multiple spike layers in the shadow Gierer-Meinhardt system: existence of equilibria and approximate invariant manifold. Duke Math. J. 98, 59–111 (1999)

    Article  MATH  MathSciNet  Google Scholar 

  30. Lazer, A.C., McKenna, P.J.: On steady state solutions of a system of reaction-diffusion equations from biology. Nonlinear Anal. 6, 523–530 (1982)

    Article  MATH  MathSciNet  Google Scholar 

  31. Leech, J.: The problem of the thirteen spheres. Math. Gaz. 40, 22–23 (1956)

    MATH  MathSciNet  Google Scholar 

  32. Nagumo, J.S., Arimoto, S., Yoshizawa, S.: An active pulse transmission line simulating nerve axon. Proc. IRE 50, 2061–2071 (1962)

    Google Scholar 

  33. Ni, W.-M., Wei, J.: On the location and profile of spike-layer solutions to singularly perturbed semilinear Dirichlet problems. Comm. Pure. Appl. Math. 48, 731–768 (1995)

    MATH  MathSciNet  Google Scholar 

  34. Nishiura, Y.: Coexistence of infinitely many stable solutions to reaction-diffusion system in the singular limit, Dynamics Reported: Expositions in Dynamical Systems, Edited by C.R.K.T. Jones, U. Kirchgraber and H.O. Walther, Vol. 3, Springer-Verlag, New York, 1994

  35. Nishiura, Y., Fujii, H.: Stability of singularly perturbed solutions to systems of reaction diffusion euations. SIAM J. Math. Anal. 18, 1726–1770 (1987)

    Article  MATH  MathSciNet  Google Scholar 

  36. Ouyang, T., Shi, J.: Exact multiplicity of positive solutions for a class of semilinear problems. J. Diff. Eqs. 146, 121–156 (1998)

    Article  MATH  MathSciNet  Google Scholar 

  37. Oshita, Y.: On stable nonconstant stationary solutions and mesoscopic patterns for FitzHugh-Nagumo equations in higher dimensions. J. Diff. Eqs. 188, 110–134 (2003)

    Article  MATH  MathSciNet  Google Scholar 

  38. Oshita, Y., Ohnishi, I.: Standing pulse solutions for the FitzHugh-Nagumo euations. Jap. J. Ind. Appl. Math. 20, 101–115 (2003)

    Article  MATH  MathSciNet  Google Scholar 

  39. Sweers, G., Troy, W.C.: On the bifurcation curve for an elliptic system of FitzHugh-Nagumo type. Phys. D 177, 1–22 (2003)

    Article  MATH  MathSciNet  Google Scholar 

  40. Reinecke, C., Sweers, G.: Solutions with internal jump for an autonomous elliptic system of FitzHugh-Nagumo type. Math. Nachr. 254, 64–87 (2003)

    Article  MathSciNet  Google Scholar 

  41. Reinecke, C., Sweers, G.: Existence and uniqueness of solutions on bounded domains to a FitzHugh-Nagumo type elliptic system. Pacific J. Math. 197, 183–211 (2001)

    Article  MATH  MathSciNet  Google Scholar 

  42. Reinecke, C., Sweers, G.: A boundary layer solution to a semilinear elliptic system of FitzHugh-Nagumo type. C. R. Acad. Sci. Paris Ser. I Math. 329, 27–32 (1999)

    MATH  MathSciNet  Google Scholar 

  43. Reinecke, C., Sweers, G.: Positive solution on R N to a system of elliptic equations of FitzHugh-Nagumo type. J. Diff. Eqs. 153, 292–312 (1999)

    Article  MATH  MathSciNet  Google Scholar 

  44. Wei, J., Winter, M.: Stationary solutions for the Cahn-Hilliard equation. Ann. Inst. H. Poincaré Anal. Non Linéaire 15, 459–492 (1998)

    Article  MATH  Google Scholar 

  45. Wei, J., Winter, M.: Multiple boundary spike solutions for a wide class of singular perturbation problems. J. London Math. Soc. 59, 585–606 (1999)

    Article  MATH  MathSciNet  Google Scholar 

  46. Wei, J., Winter, M.: Symmetric and asymmetric multiple clusters in a reaction-diffusion system. NoDEA Nonlinear Differential Equations Appl. (to appear)

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Matthias Winter.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Wei, J., Winter, M. Standing waves in the FitzHugh-Nagumo system and a problem in combinatorial geometry. Math. Z. 254, 359–383 (2006). https://doi.org/10.1007/s00209-006-0952-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00209-006-0952-8

Keywords

Mathematics Subject Classification

Navigation