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Mortality within 1 year after hip fracture surgical repair in the elderly according to postoperative period: a probabilistic record linkage study in Brazil

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Abstract

Objective

The purpose of this study was to assess, by applying probabilistic record linkage (PRL) methodology, the excess mortality and underlying causes of death in a cohort of elderly patients who underwent hip fracture surgical repair during 1995 in Rio de Janeiro, Brazil.

Discussion

We searched the Brazilian Hospital Admission Information System (HAIS) for the city of Rio de Janeiro, identifying all cases of elderly patients who had hip fracture surgery between January 1 and December 31, 1995, and by means of the PRL methodology and RecLink software, crosslinked those data with the Brazilian Mortality Information System (MIS) for the same region for a follow-up period of 1 year. We calculated age- and gender-adjusted standardized mortality ratios (SMR) for three periods of time—1–30 days, 31–90 days, and 91–365 days after hospital admission—and analyzed the basic cause of death as reported in the death certificates and noted the death occurred at the index admission or after hospital discharge.

Results

We found an overall 21.5% (95% CI 18.2–24.9) mortality rate in 1 year and a statistically significant SMR of 1,080 (95% CI 794–1450) and 512.8 (95% CI 366.4–698.3) for the first two periods, 1–30 days and 31–90 days after hospital admission, respectively. For the last period the SMR displayed a statistically nonsignificant trend of 137 (95% CI 99–183). Even in the first 15 days after the index hospital admission, most deaths (55.1%) occurred after hospital discharge, reinforcing the importance of linking hospital mortality databases with general population mortality information systems. The leading three basic causes of death, as reported in death certificates, were cardiovascular events, falls, and infections. This study represents an example of the application of PRL methodology to produce relevant data on hip fracture, a subject of rising epidemiological importance in developing countries.

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References

  1. Cummings SR, Melton LJ (2002) Epidemiology and outcomes of osteoporotic fractures. Lancet 359:1761–1767

    Article  PubMed  Google Scholar 

  2. Johnell O, Kanis JA (2005) Epidemiology of osteoporotic fractures. Osteoporos Int 16(Suppl 2):S3–S7

    Article  PubMed  Google Scholar 

  3. Gullberg B, Johnell O, Kanis JA (1997) World-wide projections for hip fracture. Osteoporos Int 7:407–413

    Article  PubMed  CAS  Google Scholar 

  4. Melton LJ 3rd (1996) Epidemiology of hip fractures: implications of the exponential increase with age. Bone 18:121S–125S

    Article  PubMed  Google Scholar 

  5. Johnell O, Kanis J (2004) An estimate of the worldwide prevalence, mortality and disability associated with hip fracture. Osteoporos Int 15:897–902

    Article  PubMed  CAS  Google Scholar 

  6. Zethraeus N, Stromberg L, Jonsson B, Svensson O, Ohlen G (1997) The cost of a hip fracture. Estimates for 1,709 patients in Sweden. Acta Orthop Scand 68:13–17

    Article  PubMed  CAS  Google Scholar 

  7. Cooper C (1997) The crippling consequences of fractures and their impact on quality of life. Am J Med 103:12S–17S; discussion 17S–19S

    Article  PubMed  CAS  Google Scholar 

  8. Center JR, Nguyen TV, Schneider D, Sambrook PN, Eisman JA (1999) Mortality after all major types of osteoporotic fracture in men and women: an observational study. Lancet 353:878–882

    Article  PubMed  CAS  Google Scholar 

  9. Trombetti A, Herrmann F, Hoffmeyer P, Schurch MA, Bonjour JP, Rizzoli R (2002) Survival and potential years of life lost after hip fracture in men and age-matched women. Osteoporos Int 13:731–737

    Article  PubMed  CAS  Google Scholar 

  10. Randell AG, Nguyen TV, Bhalerao N, Silverman SL, Sambrook PN, Eisman JA (2000) Deterioration in quality of life following hip fracture: a prospective study. Osteoporos Int 11:460–466

    Article  PubMed  CAS  Google Scholar 

  11. Kannus P, Parkkari J, Sievanen H, Heinonen A, Vuori I, Jarvinen M (1996) Epidemiology of hip fractures. Bone 18:57S–63S

    Article  PubMed  CAS  Google Scholar 

  12. Nurmi I, Narinen A, Luthje P, Tanninen S (2003) Cost analysis of hip fracture treatment among the elderly for the public health services: a 1-year prospective study in 106 consecutive patients. Arch Orthop Trauma Surg 123:551–554

    Article  PubMed  Google Scholar 

  13. Johnell O (1997) The socioeconomic burden of fractures: today and in the 21st century. Am J Med 103:20S–25S; discussion 25S–26S

    Article  PubMed  CAS  Google Scholar 

  14. De Laet CE, van Hout BA, Burger H, Weel AE, Hofman A, Pols HA (1999) Incremental cost of medical care after hip fracture and first vertebral fracture: the Rotterdam study. Osteoporos Int 10:66–72

    Article  PubMed  Google Scholar 

  15. Papaioannou A, Watts NB, Kendler DL, Yuen CK, Adachi JD, Ferko N (2002) Diagnosis and management of vertebral fractures in elderly adults. Am J Med 113:220–228

    Article  PubMed  Google Scholar 

  16. Zuckerman JD (1996) Hip fracture. N Engl J Med 334:1519–1525

    Article  PubMed  CAS  Google Scholar 

  17. Lichtblau S (2000) Hip fracture. Surgical decisions that affect medical management. Geriatrics 55:50–56

    PubMed  CAS  Google Scholar 

  18. Jain R, Basinski A, Kreder HJ (2003) Nonoperative treatment of hip fractures. Int Orthop 27:11–17

    PubMed  Google Scholar 

  19. Lu-Yao GL, Baron JA, Barrett JA, Fisher ES (1994) Treatment and survival among elderly Americans with hip fractures: a population-based study. Am J Public Health 84:1287–1291

    PubMed  CAS  Google Scholar 

  20. Lyons AR (1997) Clinical outcomes and treatment of hip fractures. Am J Med 103:51S–63S; discussion 63S–64S

    Article  PubMed  CAS  Google Scholar 

  21. Magaziner J, Lydick E, Hawkes W, Fox KM, Zimmerman SI, Epstein RS, Hebel JR (1997) Excess mortality attributable to hip fracture in white women aged 70 years and older. Am J Public Health 87:1630–1636

    PubMed  CAS  Google Scholar 

  22. Forsen L, Sogaard AJ, Meyer HE, Edna T, Kopjar B (1999) Survival after hip fracture: short- and long-term excess mortality according to age and gender. Osteoporos Int 10:73–78

    Article  PubMed  CAS  Google Scholar 

  23. Walker N, Norton R, Van der Hoorn S, Rodgers A, MacMahon S, Clark T, Gray H (1999) Mortality after hip fracture: regional variations in New Zealand. N Z Med J 112:269–271

    PubMed  CAS  Google Scholar 

  24. Yuan Z, Dawson N, Cooper GS, Einstadter D, Cebul R, Rimm AA (2001) Effects of alcohol-related disease on hip fracture and mortality: a retrospective cohort study of hospitalized Medicare beneficiaries. Am J Public Health 91:1089–1093

    PubMed  CAS  Google Scholar 

  25. Goldacre MJ, Roberts SE, Yeates D (2002) Mortality after admission to hospital with fractured neck of femur: database study. BMJ 325:868–869

    Article  PubMed  Google Scholar 

  26. Farahmand BY, Michaelsson K, Ahlbom A, Ljunghall S, Baron JA (2005) Survival after hip fracture. Osteoporos Int 16:1583–1590

    Article  PubMed  Google Scholar 

  27. Franzo A, Francescutti C, Simon G (2005) Risk factors correlated with post-operative mortality for hip fracture surgery in the elderly: a population-based approach. Eur J Epidemiol 20:985–991

    Article  PubMed  Google Scholar 

  28. Karagiannis A, Papakitsou E, Dretakis K, Galanos A, Megas P, Lambiris E, Lyritis GP (2006) Mortality rates of patients with a hip fracture in a southwestern district of Greece: ten-year follow-up with reference to the type of fracture. Calcif Tissue Int 78:72–77

    Article  PubMed  CAS  Google Scholar 

  29. Wehren LE, Hawkes WG, Orwig DL, Hebel JR, Zimmerman SI, Magaziner J (2003) Gender differences in mortality after hip fracture: the role of infection. J Bone Miner Res 18:2231–2237

    Article  PubMed  Google Scholar 

  30. Johnell O, Kanis JA, Oden A, Sernbo I, Redlund-Johnell I, Petterson C, De Laet C, Jonsson B (2004) Mortality after osteoporotic fractures. Osteoporos Int 15:38–42

    Article  PubMed  CAS  Google Scholar 

  31. Siqueira FV, Facchini LA, Hallal PC (2005) The burden of fractures in Brazil: a population-based study. Bone 37:261–266

    Article  PubMed  Google Scholar 

  32. Goldacre MJ, Griffith M, Gill L, Mackintosh A (2002) In-hospital deaths as fraction of all deaths within 30 days of hospital admission for surgery: analysis of routine statistics. BMJ 324:1069–1070

    Article  PubMed  Google Scholar 

  33. Jaro M (1989) Advances in record-linkage methodology as applied to matching the 1985 Census of Tampa, Florida. J Am Stat Assoc 84:414–420

    Article  Google Scholar 

  34. Jaro M (1995) Probabilistic linkage of large public health data files. Stat Med 14:491–498

    Article  PubMed  CAS  Google Scholar 

  35. Camargo Jr KR, Coeli CM (2000) [Reclink: an application for database linkage implementing the probabilistic record linkage method]. Cad Saude Publica 16:439–447

    PubMed  Google Scholar 

  36. Schwartz AV, Kelsey JL, Maggi S, Tuttleman M, Ho SC, Jonsson PV, Poor G, Sisson de Castro JA, Xu L, Matkin CC, Nelson LM, Heyse SP (1999) International variation in the incidence of hip fractures: cross-national project on osteoporosis for the World Health Organization Program for Research on Aging. Osteoporos Int 9:242–253

    Article  PubMed  CAS  Google Scholar 

  37. Komatsu RS, Simões MFJ, Ramos LR, Szejnfeld VL (1999) Incidência de fraturas de fêmur proximal em Marília, São Paulo, Brasil, 1994 e 1995. Rev Bras Reumat 39:325–331

    Google Scholar 

  38. Silveira VA, Medeiros MM, Coelho-Filho JM, Mota RS, Noleto JC, Costa FS, Pontes FJ, Sobral JB, Aguiar RF, Leal AC, Clemente CM (2005) Hip fracture incidence in an urban area in Northeast Brazil. Cad Saude Publica 21:907–912

    PubMed  Google Scholar 

  39. Castro da Rocha FA, Ribeiro AR (2003) Low incidence of hip fractures in an equatorial area. Osteoporos Int 14:496–499

    Article  PubMed  Google Scholar 

  40. Roberts SE, Goldacre MJ (2003) Time trends and demography of mortality after fractured neck of femur in an English population, 1968–98: database study. BMJ 327:771–775

    Article  PubMed  Google Scholar 

  41. Cauley JA, Thompson DE, Ensrud KC, Scott JC, Black D (2000) Risk of mortality following clinical fractures. Osteoporos Int 11:556–561

    Article  PubMed  CAS  Google Scholar 

  42. Kanis JA, Oden A, Johnell O, De Laet C, Jonsson B, Oglesby AK (2003) The components of excess mortality after hip fracture. Bone 32:468–473

    Article  PubMed  CAS  Google Scholar 

  43. Krieger N, Davey Smith G (2004) “Bodies count,” and body counts: social epidemiology and embodying inequality. Epidemiol Rev 26:92–103

    Article  PubMed  Google Scholar 

  44. Samelson EJ, Zhang Y, Kiel DP, Hannan MT, Felson DT (2002) Effect of birth cohort on risk of hip fracture: age-specific incidence rates in the Framingham Study. Am J Public Health 92:858–862

    Article  PubMed  Google Scholar 

  45. Meyer HE, Tverdal A, Falch JA, Pedersen JI (2000) Factors associated with mortality after hip fracture. Osteoporos Int 11:228–232

    Article  PubMed  CAS  Google Scholar 

  46. Katelaris AG, Cumming RG (1996) Health status before and mortality after hip fracture. Am J Public Health 86:557–560

    PubMed  CAS  Google Scholar 

  47. Tjeenk R, Shepers A, van de Linde P, Breslau P, Peeters M (2002) Mortality registration in patients with a proximal femoral fracture admitted to a surgical ward. Eur J Trauma 28:95–99

    Article  Google Scholar 

  48. Poole KE, Reeve J, Warburton EA (2002) Falls, fractures, and osteoporosis after stroke: time to think about protection? Stroke 33:1432–1436

    Article  PubMed  Google Scholar 

  49. Handoll HH, Sherrington C, Parker MJ (2005) Mobilisation strategies after hip fracture surgery in adults. The Cochrane Library, issue 2. Update Software, Oxford

    Google Scholar 

  50. Seiler W (2000) Consequences of immobility. In: Evans JG (ed) Oxford textbook of geriatric medicine. Oxford University Press, Oxford, pp 1175–1181

    Google Scholar 

  51. Kane R, Ouslander, J, Abrass I (2003) Immobility. In: Kane R, Ouslander J, Abrass I (eds) Essentials of clinical geriatrics. McGraw-Hill, New York, pp 245–277

    Google Scholar 

  52. Browner WS, Seeley DG, Vogt TM, Cummings SR (1991) Non-trauma mortality in elderly women with low bone mineral density. Study of Osteoporotic Fractures Research Group. Lancet 338:355–358

    Article  PubMed  CAS  Google Scholar 

  53. Johansson C, Black D, Johnell O, Oden A, Mellstrom D (1998) Bone mineral density is a predictor of survival. Calcif Tissue Int 63:190–196

    Article  PubMed  CAS  Google Scholar 

  54. Hamerman D (2005) Osteoporosis and atherosclerosis: biological linkages and the emergence of dual-purpose therapies. QJM 98:467–484

    Article  PubMed  CAS  Google Scholar 

  55. Nawroth P, Pirzer R, Fohr B, Schilling T, Ziegler R, Bierhaus A, Kasperk C (2003) [Osteoporosis and cardiovascular disease-two sides of the same coin?]. Med Klin (Munich) 98:437–446

    Article  CAS  Google Scholar 

  56. Strausbaugh L (2001) Emerging health care-associated infections in the geriatric population. Emerg Infect Dis 7:268–271

    Article  PubMed  CAS  Google Scholar 

  57. Falsey AR (2000) Epidemiology of infectious diseases. In: Evans JG (ed) Oxford textbook of geriatric medicine. Oxford University Press, Oxford, pp 55–64

    Google Scholar 

  58. Colón-Emeric C, Sloane R, Hawkes W, Magaziner J, Zimmerman S, Pieper C, Lyles K (2000) The risk of subsequent fracture in community-dwelling men and male veterans with hip fracture. Am J Med 109:324–326

    Article  PubMed  Google Scholar 

  59. [No authors listed] (1995) Computerised record linkage: compared with traditional patient follow-up methods in clinical trials and illustrated in a prospective epidemiological study. The West of Scotland Coronary Prevention Study Group. J Clin Epidemiol 48:1441–1452

    Google Scholar 

  60. Shannon HS, Jamieson E, Walsh C, Julian JA, Fair ME, Buffet A (1989) Comparison of individual follow-up and computerized record linkage using the Canadian Mortality Data Base. Can J Public Health 80:54–57

    PubMed  CAS  Google Scholar 

  61. Partanen J, Syrjala H, Vahanikkila H, Jalovaara P (2006) Impact of deep infection after hip fracture surgery on function and mortality. J Hosp Infect 62:44–49

    Article  PubMed  CAS  Google Scholar 

  62. Levcovitz E, Pereira T (1993) Uma Ánalise do Sistema Público de Remuneração de Internações Hospitalares. Série Est Saúde Col UERJ 57:1–83

    Google Scholar 

  63. Castro MSM, Travassos C, Carvalho MS (2002) [Analysis of hospital admissions associated factors in Brazil]. Ciênc Saúde Coletiva 7:795–811

    Article  Google Scholar 

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Correspondence to E. I. O. Vidal.

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Funding

This project was sponsored by the Brazilian National Council for Scientific and Technological Development (CNPq), Edital CNPq 19/2004, (471562/2004-1).

Appendix

Appendix

Here we list some software packages that implement some or all of the procedures of the PRL methodology:

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Vidal, E.I.O., Coeli, C.M., Pinheiro, R.S. et al. Mortality within 1 year after hip fracture surgical repair in the elderly according to postoperative period: a probabilistic record linkage study in Brazil. Osteoporos Int 17, 1569–1576 (2006). https://doi.org/10.1007/s00198-006-0173-3

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