Skip to main content

Advertisement

Log in

Significance of osteoporosis in craniomaxillofacial surgery: A review of the literature

  • Review
  • Published:
Osteoporosis International Aims and scope Submit manuscript

Abstract

Osteoporosis is a common problem in orthopedic surgery. The purpose of this review of the literature was to examine whether osteoporosis is also an important factor in patient treatment in the field of craniomaxillofacial surgery. Emphasis was given to the consequences of osteoporosis for the maxilla and mandible, the influence of osteoporosis on fracture treatment, the use of dental implants, the importance of soft tissues and the effect of osteoporosis therapies. It was found that osteoporosis does affect the bones of the skull. The effect of osteoporosis on treatment, however, is controversial and necessitates better ways of quantifying bone loss. Large inter-individual and site-specific differences in bone density, as well as other effects such as removal of teeth, periodontitis, implant insertion, augmentation procedures and altered loading with dystrophic consequences need to be considered in future studies. Special attention should be given to osteoporosis during fracture treatment.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

References

  1. Lill CA, Hesseln J, Schlegel U, Eckhardt C, Goldhahn J, Schneider E (2003) Biomechanical evaluation of healing in a non-critical defect in a large animal model of osteoporosis. J Orthop Res 21(5):836–842

    Google Scholar 

  2. Goldhahn J, Jenet A, Neuhoff D, Schneider E, Lill CA (2003) Auswirkung von hauptsaechlich steroidinduzierter Osteoporose auf die Frakturheilung am Tiermodell—Oral Presentation. Osteologie 12 [Suppl. 1]:44

  3. (1993) Consensus Development Conference on Osteoporosis. Hong Kong, April 1–2, 1993. Am J Med 95(5A):1S–78S

  4. (1993) Consensus development conference: diagnosis, prophylaxis, and treatment of osteoporosis. Am J Med 94(6):646–650

  5. Kanis JA (1994) Assessment of fracture risk and its application to screening for postmenopausal osteoporosis: synopsis of a WHO report. WHO Study Group. Osteoporos Int 4(6):368–381

    Google Scholar 

  6. Kanis JA, Melton LJ III, Christiansen C, Johnston CC, Khaltaev N (1994) The diagnosis of osteoporosis. J Bone Miner Res 9(8):1137–1141

    Google Scholar 

  7. Miller PD, Bonnick SL, Rosen CJ (1996) Consensus of an international panel on the clinical utility of bone mass measurements in the detection of low bone mass in the adult population. Calcif Tissue Int 58(4):207–214

    Google Scholar 

  8. Yamazaki M, Shirota T, Tokugawa Y, Motohashi M, Ohno K, Michi K, Yamaguchi A (1999) Bone reactions to titanium screw implants in ovariectomized animals. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 87(4):411–418

    Google Scholar 

  9. Habets LL, Bras J, Borgmeyer-Hoelen AM (1988) Mandibular atrophy and metabolic bone loss. Endocrinology, radiology and histomorphometry. Int J Oral Maxillofac Surg 17(3):208–211

    Google Scholar 

  10. Morrison NA, Qi JC, Tokita A, Kelly PJ, Crofts L, Nguyen TV, Sambrook PN, Eisman JA (1994) Prediction of bone density from vitamin D receptor alleles. Nature 367(6460):284–287

    Google Scholar 

  11. Prentice A (2004) Diet, nutrition and the prevention of osteoporosis. Public Health Nutr 7(1A):227–243

    Google Scholar 

  12. Schacht E (1994) [Differential therapy of osteoporosis—an overview based on recent findings regarding the pathogenesis]. Z Rheumatol 53(5):274–298

    Google Scholar 

  13. Seeman E, Eisman JA (2004) 7: Treatment of osteoporosis: why, whom, when and how to treat. The single most important consideration is the individual’s absolute risk of fracture. Med J Aust 180(6):298–303

    Google Scholar 

  14. Becker W, Hujoel PP, Becker BE, Willingham H (2000) Osteoporosis and implant failure: an exploratory case-control study. J Periodontol 71(4):625–631

    Google Scholar 

  15. Bras J, Van Ooij CP, Van den Akker HP (1985) Mandibular atrophy and metabolic bone loss. Mandibular ridge augmentation by combined sandwich-visor osteotomy and resorption related to metabolic bone state. Int J Oral Surg 14(1):16–21

    Google Scholar 

  16. Klemetti E, Vainio P, Lassila V, Alhava E (1993) Cortical bone mineral density in the mandible and osteoporosis status in postmenopausal women. Scand J Dent Res 101(4):219–223

    Google Scholar 

  17. Kribbs PJ, Smith DE, Chesnut CH III (1983) Oral findings in osteoporosis. Part II: Relationship between residual ridge and alveolar bone resorption and generalized skeletal osteopenia. J Prosthet Dent 50(5):719–724

    Google Scholar 

  18. Kribbs PJ, Chesnut CH III, Ott SM, Kilcoyne RF (1989) Relationships between mandibular and skeletal bone in an osteoporotic population. J Prosthet Dent 62(6):703–707

    Google Scholar 

  19. Taguchi A, Tanimoto K, Suei Y, Ohama K, Wada T (1996) Relationship between the mandibular and lumbar vertebral bone mineral density at different postmenopausal stages. Dentomaxillofac Radiol 25(3):130–135

    Google Scholar 

  20. von Wowern N (1985) In vivo measurement of bone mineral content of mandibles by dual-photon absorptiometry. Scand J Dent Res 93(2):162–168

    Google Scholar 

  21. Lindh C, Nilsson M, Klinge B, Petersson A (1996) Quantitative computed tomography of trabecular bone in the mandible. Dentomaxillofac Radiol 25(3):146–150

    Google Scholar 

  22. Beer A, Gahleitner A, Holm A, Tschabitscher M, Homolka P (2003) Correlation of insertion torques with bone mineral density from dental quantitative CT in the mandible. Clin Oral Implants Res 14(5):616–620

    Google Scholar 

  23. Taguchi A, Suei Y, Ohtsuka M, Otani K, Tanimoto K, Hollender LG (1999) Relationship between bone mineral density and tooth loss in elderly Japanese women. Dentomaxillofac Radiol 28(4):219–223

    Google Scholar 

  24. von Wowern N, Kollerup G (1992) Symptomatic osteoporosis: a risk factor for residual ridge reduction of the jaws. J Prosthet Dent 67(5):656–660

    Google Scholar 

  25. White SC (2002) Oral radiographic predictors of osteoporosis. Dentomaxillofac Radiol 31(2):84–92

    Google Scholar 

  26. Horner K, Devlin H, Alsop CW, Hodgkinson IM, Adams JE (1996) Mandibular bone mineral density as a predictor of skeletal osteoporosis. Br J Radiol 69(827):1019–1025

    Google Scholar 

  27. Jonasson G, Kiliaridis S, Gunnarsson R (1999) Cervical thickness of the mandibular alveolar process and skeletal bone mineral density. Acta Odontol Scand 57(3):155–161

    Google Scholar 

  28. Klemetti E, Vainio P, Lassila V, Alhava E (1993) Trabecular bone mineral density of mandible and alveolar height in postmenopausal women. Scand J Dent Res 101(3):166–170

    Google Scholar 

  29. Klemetti E, Vainio P (1993) Effect of bone mineral density in skeleton and mandible on extraction of teeth and clinical alveolar height. J Prosthet Dent 70(1):21–25

    Google Scholar 

  30. Klemetti E, Kroger H, Lassila V (1997) Relationship between body mass index and the remaining alveolar ridge. J Oral Rehabil 24(11):808–812

    Google Scholar 

  31. Verna C, Melsen B, Melsen F (1999) Differences in static cortical bone remodeling parameters in human mandible and iliac crest. Bone 25(5):577–583

    Google Scholar 

  32. von Wowern N, Stoltze K (1979) Age differences in cortical width of mandibles determined by histoquantitation. Scand J Dent Res 87(3):225–233

    Google Scholar 

  33. von Wowern N, Klausen B, Kollerup G (1994) Osteoporosis: a risk factor in periodontal disease. J Periodontol 65(12):1134–1138

    Google Scholar 

  34. Devlin H, Ferguson MW (1991) Alveolar ridge resorption and mandibular atrophy. A review of the role of local and systemic factors. Br Dent J 170(3):101–104

    Google Scholar 

  35. Gallagher JC, Goldgar D, Moy A (1987) Total bone calcium in normal women: effect of age and menopause status. J Bone Miner Res 2(6):491–496

    Google Scholar 

  36. Klemetti E, Vainio P, Lassila V (1994) Mineral density in the mandibles of partially and totally edentate postmenopausal women. Scand J Dent Res 102(1):64–67

    Google Scholar 

  37. Kribbs PJ, Chesnut CH III, Ott SM, Kilcoyne RF (1990) Relationships between mandibular and skeletal bone in a population of normal women. J Prosthet Dent 63(1):86–89

    Google Scholar 

  38. von Wowern N (1986) Bone mass of mandibles. In vitro and in vivo analyses. Dan Med Bull 33(1):23–44

    Google Scholar 

  39. Cummings SR, Black D (1995) Bone mass measurements and risk of fracture in Caucasian women: a review of findings from prospective studies. Am J Med 98(2A):24S–28S

    Google Scholar 

  40. Dao TT, Anderson JD, Zarb GA (1993) Is osteoporosis a risk factor for osseointegration of dental implants? Int J Oral Maxillofac Implants 8(2):137–144

    Google Scholar 

  41. Klinge B, Johansson C, Albrektsson T, Hallstrom H, Engdahl T (1995) A new method to obtain bone biopsies at implant sites peri-operatively: technique and bone structure. Clin Oral Implants Res 6(2):91–95

    Google Scholar 

  42. Bryant SR (1998) The effects of age, jaw site, and bone condition on oral implant outcomes. Int J Prosthodont 11(5):470–490

    Google Scholar 

  43. Kreisler M, Behneke N, Behneke A, d’Hoedt B (2003) Residual ridge resorption in the edentulous maxilla in patients with implant-supported mandibular overdentures: an 8-year retrospective study. Int J Prosthodont 16(3):295–300

    Google Scholar 

  44. Atwood DA, Coy WA (1971) Clinical, cephalometric, and densitometric study of reduction of residual ridges. J Prosthet Dent 26(3):280–295

    Google Scholar 

  45. Habets LL, Bras J, van Merkesteyn JP (1988) Mandibular atrophy and metabolic bone loss. Histomorphometry of iliac crest biopsies in 74 patients. Int J Oral Maxillofac Surg 17(5):325–329

    Google Scholar 

  46. Hirai T, Ishijima T, Hashikawa Y, Yajima T (1993) Osteoporosis and reduction of residual ridge in edentulous patients. J Prosthet Dent 69(1):49–56

    Google Scholar 

  47. Goldberg AF, Gergans GA, Mattson DE, Rudman D (1988) Radiographic alveolar process/mandibular height ratio as a predictor of osteoporosis. Gerodontics 4(5):229–231

    Google Scholar 

  48. Mercier P, Inoue S (1981) Bone density and serum minerals in cases of residual alveolar ridge atrophy. J Prosthet Dent 46(3):250–255

    Google Scholar 

  49. Johnson RB, Gilbert JA, Cooper RC, Dai X, Newton BI, Tracy RR, West WF, DeMoss TL, Myers PJ, Streckfus CF (1997) Alveolar bone loss one year following ovariectomy in sheep. J Periodontol 68(9):864–871

    Google Scholar 

  50. Johnson RB, Gilbert JA, Cooper RC, Parsell DE, Stewart BA, Dai X, Nick TG, Streckfus CF, Butler RA, Boring JG (2002) Effect of estrogen deficiency on skeletal and alveolar bone density in sheep. J Periodontol 73(4):383–391

    Google Scholar 

  51. Streckfus CF, Johnson RB, Nick T, Tsao A, Tucci M (1997) Comparison of alveolar bone loss, alveolar bone density and second metacarpal bone density, salivary and gingival crevicular fluid interleukin-6 concentrations in healthy premenopausal and postmenopausal women on estrogen therapy. J Gerontol A Biol Sci Med Sci 52(6):343–351

    Google Scholar 

  52. Elders PJ, Habets LL, Netelenbos JC, van der Linden LW, van der Stelt PF (1992) The relation between periodontitis and systemic bone mass in women between 46 and 55 years of age. J Clin Periodontol 19(7):492–496

    Google Scholar 

  53. Jeffcoat MK (1998) Osteoporosis: a possible modifying factor in oral bone loss. Ann Periodontol 3(1):312–321

    Google Scholar 

  54. Mohammad AR, Jones JD, Brunsvold MA (1994) Osteoporosis and periodontal disease: a review. J Calif Dent Assoc 22(3):69–75

    Google Scholar 

  55. von Wowern N, Westergaard J, Kollerup G (2001) Bone mineral content and bone metabolism in young adults with severe periodontitis. J Clin Periodontol 28(6):583–588

    Google Scholar 

  56. Wactawski-Wende J, Grossi SG, Trevisan M, Genco RJ, Tezal M, Dunford RG, Ho AW, Hausmann E, Hreshchyshyn MM (1996) The role of osteopenia in oral bone loss and periodontal disease. J Periodontol 67[Suppl 10]:1076–1084

  57. Hildebolt CF, Zerbolio DJ Jr, Shrout MK, Ritzi S, Gravier MJ (1992) Radiometric classification of alveolar bone health. J Dent Res 71(9):1594–1597

    Google Scholar 

  58. Mattson JS, Cerutis DR, Parrish LC (2002) Osteoporosis: a review and its dental implications. Compend Contin Educ Dent 23(11):1001–1004

    Google Scholar 

  59. Bando K, Nitta H, Matsubara M, Ishikawa I (1998) Bone mineral density in periodontally healthy and edentulous postmenopausal women. Ann Periodontol 3(1):322–326

    Google Scholar 

  60. Krejci CB (1996) Osteoporosis and periodontal disease: is there a relationship? J West Soc Periodontol Periodontal Abstr 44(2):37–42

    Google Scholar 

  61. Reddy MS (2001) Osteoporosis and periodontitis: discussion, conclusions, and recommendations. Ann Periodontol 6(1):214–217

    Google Scholar 

  62. Chesnut CH 3rd (2001) The relationship between skeletal and oral bone mineral density: an overview. Ann Periodontol 6(1):193–196

    Google Scholar 

  63. Payne JB, Reinhardt RA, Nummikoski PV, Dunning DG, Patil KD (2000) The association of cigarette smoking with alveolar bone loss in postmenopausal females. J Clin Periodontol 27(9):658–664

    Google Scholar 

  64. Minsk L, Polson AM (1998) Dental implant outcomes in postmenopausal women undergoing hormone replacement. Compend Contin Educ Dent 19(9):859–862, 864

    Google Scholar 

  65. Olszynski WP, Shawn DK, Adachi JD, Brown JP, Cummings SR, Hanley DA, Harris SP, Hodsman AB, Kendler D, McClung MR, Miller PD, Yuen CK (2004) Osteoporosis in men: epidemiology, diagnosis, prevention, and treatment. Clin Ther 26(1):15–28

    Google Scholar 

  66. Jensen J, Christiansen C, Rodbro P (1985) Cigarette smoking, serum estrogens, and bone loss during hormone-replacement therapy early after menopause. N Engl J Med 313(16):973–975

    Google Scholar 

  67. Bochlogyros PN (1985) Non-union of fractures of the mandible. J Maxillofac Surg 13(4):189–193

    Google Scholar 

  68. Bruce RA, Ellis E III (1993) The second Chalmers J. Lyons Academy study of fractures of the edentulous mandible. J Oral Maxillofac Surg 51(8):904–911

    Google Scholar 

  69. Buchbinder D (1993) Treatment of fractures of the edentulous mandible, 1943 to 1993: a review of the literature. J Oral Maxillofac Surg 51(11):1174–1180

    Google Scholar 

  70. Kunz C, Hammer B, Prein J (2001) [Fractures of the edentulous atrophic mandible. Fracture management and complications]. Mund Kiefer Gesichtschir 5(4):227–232

    Google Scholar 

  71. Amaratunga NA (1988) A comparative study of the clinical aspects of edentulous and dentulous mandibular fractures. J Oral Maxillofac Surg 46(1):3–5

    Google Scholar 

  72. Bruce RA, Strachan DS (1976) Fractures of the edentulous mandible: the Chalmer J Lyons Academy study. J Oral Surg 34(11):973–979

    Google Scholar 

  73. Krebs FJ III (1988) Dynamic compression plating in treatment of the fractured, edentulous mandible. Laryngoscope 98(2):198–201

    Google Scholar 

  74. Luhr HG, Reidick T, Merten HA (1996) Results of treatment of fractures of the atrophic edentulous mandible by compression plating: a retrospective evaluation of 84 consecutive cases. J Oral Maxillofac Surg 54(3):250–254

    Google Scholar 

  75. Obwegeser HL, Sailer HF (1973) Another way of treating fractures of the atrophic edentulous mandible. J Maxillofac Surg 1(4):213–221

    Google Scholar 

  76. Thaller SR (1993) Fractures of the edentulous mandible: a retrospective review. J Craniofac Surg 4(2):91–94

    Google Scholar 

  77. Falcone PA, Haedicke GJ, Brooks G, Sullivan PK (1990) Maxillofacial fractures in the elderly: a comparative study. Plast Reconstr Surg 86(3):443–448

    Google Scholar 

  78. Gerbino G, Roccia F, De Gioanni PP, Berrone S (1999) Maxillofacial trauma in the elderly. J Oral Maxillofac Surg 57(7):777–782

    Google Scholar 

  79. Hussain K, Wijetunge DB, Grubnic S, Jackson IT (1994) A comprehensive analysis of craniofacial trauma. J Trauma 36(1):34–47

    Google Scholar 

  80. Chew DJ, Edmondson HD (1996) A study of maxillofacial injuries in the elderly resulting from falls. J Oral Rehabil 23(7):505–509

    Google Scholar 

  81. Fasola AO, Obiechina AE, Arotiba JT (2003) Incidence and pattern of maxillofacial fractures in the elderly. Int J Oral Maxillofac Surg 32(2):206–208

    Google Scholar 

  82. Goldschmidt MJ, Castiglione CL, Assael LA, Litt MD (1995) Craniomaxillofacial trauma in the elderly. J Oral Maxillofac Surg 53(10):1145–1149

    Google Scholar 

  83. Werning JW, Downey NM, Brinker RA, Khuder SA, Davis WJ, Rubin AM, Elsamaloty HM (2004) The impact of osteoporosis on patients with maxillofacial trauma. Arch Otolaryngol Head Neck Surg 130(3):353–356

    Google Scholar 

  84. Gilbert GH, Minaker KL (1990) Principles of surgical risk assessment of the elderly patient. J Oral Maxillofac Surg 48(9):972–979

    Google Scholar 

  85. Santora TA, Schinco MA, Trooskin SZ (1994) Management of trauma in the elderly patient. Surg Clin North Am 74(1):163–186

    Google Scholar 

  86. Oreskovich MR, Howard JD, Copass MK, Carrico CJ (1984) Geriatric trauma: injury patterns and outcome. J Trauma 24(7):565–572

    Google Scholar 

  87. Iida S, Reuther T, Kogo M, Matsuya T, Muhling J (2002) [Retrospective analysis of facial fractures related to falls in 260 Japanese patients]. Mund Kiefer Gesichtschir 6(6):421–426

    Google Scholar 

  88. Levine PA, Goode RL (1982) Treatment of fractures of the edentulous mandible. Arch Otolaryngol 108(3):167–173

    Google Scholar 

  89. Levine PA (1987) AO compression plating technique for treating fractures of the edentulous mandible. Otolaryngol Clin North Am 20(3):457–477

    Google Scholar 

  90. Alpert B, Gutwald R, Schmelzeisen R (2003) New innovations in craniomaxillofacial fixation: the 2.0 lock system. Keio J Med 52(2):120–127

    Google Scholar 

  91. Ellis E III, Graham J (2002) Use of a 2.0-mm locking plate/screw system for mandibular fracture surgery. J Oral Maxillofac Surg 60(6):642–645

    Google Scholar 

  92. Gutwald R, Alpert B, Schmelzeisen R (2003) Principle and stability of locking plates. Keio J Med 52(1):21–24

    Google Scholar 

  93. Haug RH, Street CC, Goltz M (2002) Does plate adaptation affect stability? A biomechanical comparison of locking and nonlocking plates. J Oral Maxillofac Surg 60(11):1319–1326

    Google Scholar 

  94. Esposito M, Hirsch JM, Lekholm U, Thomsen P (1998) Biological factors contributing to failures of osseointegrated oral implants. (I). Success criteria and epidemiology. Eur J Oral Sci 106(1):527–551

    Google Scholar 

  95. Esposito M, Hirsch JM, Lekholm U, Thomsen P (1998) Biological factors contributing to failures of osseointegrated oral implants. (II). Etiopathogenesis. Eur J Oral Sci 106(3):721–764

    Google Scholar 

  96. August M, Chung K, Chang Y, Glowacki J (2001) Influence of estrogen status on endosseous implant osseointegration. J Oral Maxillofac Surg 59(11):1285–1289

    Google Scholar 

  97. Friberg B, Ekestubbe A, Sennerby L (2002) Clinical outcome of Branemark System implants of various diameters: a retrospective study. Int J Oral Maxillofac Implants 17(5):671–677

    Google Scholar 

  98. Higuchi KW (2000) The zygomaticus fixture: an alternative approach for implant anchorage in the posterior maxilla. Ann R Australas Coll Dent Surg 15:28–33

    Google Scholar 

  99. Hutton JE, Heath MR, Chai JY, Harnett J, Jemt T, Johns RB, McKenna S, McNamara DC, van Steenberghe D, Taylor R (1995) Factors related to success and failure rates at 3-year follow-up in a multicenter study of overdentures supported by Branemark implants. Int J Oral Maxillofac Implants 10(1):33–42

    Google Scholar 

  100. Jemt T, Bergendal B, Arvidson K, Bergendal T, Karlsson LD, Linden B, Rundcrantz T, Wendelhag I (2002) Implant-supported welded titanium frameworks in the edentulous maxilla: a 5-year prospective multicenter study. Int J Prosthodont 15(6):544–548

    Google Scholar 

  101. Jemt T, Henry P, Linden B, Naert I, Weber H, Wendelhag I (2003) Implant-supported laser-welded titanium and conventional cast frameworks in the partially edentulous law: a 5-year prospective multicenter study. Int J Prosthodont 16(4):415–421

    Google Scholar 

  102. O’Sullivan D, Sennerby L, Meredith N (2000) Measurements comparing the initial stability of five designs of dental implants: a human cadaver study. Clin Implant Dent Relat Res 2(2):85–92

    Google Scholar 

  103. Trisi P, Lazzara R, Rao W, Rebaudi A (2002) Bone-implant contact and bone quality: evaluation of expected and actual bone contact on machined and osseotite implant surfaces. Int J Periodontics Restorative Dent 22(6):535–545

    Google Scholar 

  104. Blomqvist JE, Alberius P, Isaksson S, Linde A, Hansson BG (1996) Factors in implant integration failure after bone grafting: an osteometric and endocrinologic matched analysis. Int J Oral Maxillofac Surg 25(1):63–68

    Google Scholar 

  105. Friberg B, Ekestubbe A, Mellstrom D, Sennerby L (2001) Branemark implants and osteoporosis: a clinical exploratory study. Clin Implant Dent Relat Res 3(1):50–56

    Google Scholar 

  106. Hildebrand H, Ehrenfeld M, Schneider F, Goerlich R, Goerlich H, Spitz J, Wolf J, Delling G (1994) [Possibilities for preoperative determination of transplant quality using an osteoporosis index]. Fortschr Kiefer Gesichtschir 39:34–39

    Google Scholar 

  107. Smith RA, Berger R, Dodson TB (1992) Risk factors associated with dental implants in healthy and medically compromised patients. Int J Oral Maxillofac Implants 7(3):367–372

    Google Scholar 

  108. von Wowern N, Gotfredsen K (2001) Implant-supported overdentures, a prevention of bone loss in edentulous mandibles? A 5-year follow-up study. Clin Oral Implants Res 12(1):19–25

    Google Scholar 

  109. Johns RB, Jemt T, Heath MR, Hutton JE, McKenna S, McNamara DC, van Steenberghe D, Taylor R, Watson RM, Herrmann I (1992) A multicenter study of overdentures supported by Branemark implants. Int J Oral Maxillofac Implants 7(4):513–522

    Google Scholar 

  110. Garg AK, Winkler S, Bakaeen LG, Mekayarajjananonth T (1997) Dental implants and the geriatric patient. Implant Dent 6(3):168–173

    Google Scholar 

  111. Deporter DA, Todescan R, Nardini K (1999) Use of a tapered, porous-surfaced dental implant in combination with osteotomes to restore edentulism in the difficult maxilla. Implant Dent 8(3):233–240

    Google Scholar 

  112. Friberg B, Grondahl K, Lekholm U, Branemark PI (2000) Long-term follow-up of severely atrophic edentulous mandibles reconstructed with short Branemark implants. Clin Implant Dent Relat Res 2(4):184–189

    Google Scholar 

  113. Jaffin RA, Berman CL (1991) The excessive loss of Branemark fixtures in type IV bone: a 5-year analysis. J Periodontol 62(1):2–4

    Google Scholar 

  114. Jemt T, Lekholm U (1995) Implant treatment in edentulous maxillae: a 5-year follow-up report on patients with different degrees of jaw resorption. Int J Oral Maxillofac Implants 10(3):303–311

    Google Scholar 

  115. Morris HE, Ochi S, Crum P, Orenstein I, Plezia R (2003) Bone density: its influence on implant stability after uncovering. J Oral Implantol 29(6):263–269

    Google Scholar 

  116. Ekelund JA, Lindquist LW, Carlsson GE, Jemt T (2003) Implant treatment in the edentulous mandible: a prospective study on Branemark system implants over more than 20 years. Int J Prosthodont 16(6):602–608

    Google Scholar 

  117. Kronstrom M, Widbom T, Lofquist LE, Henningson C, Widbom C, Lundberg T (2003) Early functional loading of conical Branemark implants in the edentulous mandible: a 12-month follow-up clinical report. J Prosthet Dent 89(4):335–340

    Google Scholar 

  118. Adell R, Lekholm U, Rockler B, Branemark PI (1981) A 15-year study of osseointegrated implants in the treatment of the edentulous jaw. Int J Oral Surg 10(6):387–416

    Google Scholar 

  119. Baxter JC, Fattore L (1993) Osteoporosis and osseointegration of implants. J Prosthodont 2(2):120–125

    Google Scholar 

  120. Bryant SR, Zarb GA (2002) Outcomes of implant prosthodontic treatment in older adults. J Can Dent Assoc 68(2):97–102

    Google Scholar 

  121. Cooper LF (2000) Systemic effectors of alveolar bone mass and implications in dental therapy. Periodontol 2000 23:103–109

    Google Scholar 

  122. Elsubeihi ES, Zarb GA (2002) Implant prosthodontics in medically challenged patients: the University of Toronto experience. J Can Dent Assoc 68(2):103–108

    Google Scholar 

  123. Davarpanah M, Martinez H, Kebir M, Etienne D, Tecucianu JF (2001) Wide-diameter implants: new concepts. Int J Periodontics Restorative Dent 21(2):149–159

    Google Scholar 

  124. Martinez H, Davarpanah M, Missika P, Celletti R, Lazzara R (2001) Optimal implant stabilization in low density bone. Clin Oral Implants Res 12(5):423–432

    Google Scholar 

  125. Steigenga JT, al Shammari KF, Nociti FH, Misch CE, Wang HL (2003) Dental implant design and its relationship to long-term implant success. Implant Dent 12(4):306–317

    Google Scholar 

  126. Eder A, Watzek G (1999) Treatment of a patient with severe osteoporosis and chronic polyarthritis with fixed implant-supported prosthesis: a case report. Int J Oral Maxillofac Implants 14(4):587–590

    Google Scholar 

  127. Friberg B (1994) Treatment with dental implants in patients with severe osteoporosis: a case report. Int J Periodontics Restorative Dent 14(4):348–353

    Google Scholar 

  128. Fujimoto T, Niimi A, Nakai H, Ueda M (1996) Osseointegrated implants in a patient with osteoporosis: a case report. Int J Oral Maxillofac Implants 11(4):539–542

    Google Scholar 

  129. Starck WJ, Epker BN (1995) Failure of osseointegrated dental implants after diphosphonate therapy for osteoporosis: a case report. Int J Oral Maxillofac Implants 10(1):74–78

    Google Scholar 

  130. Misch CE, Hoar J, Beck G, Hazen R, Misch CM (1998) A bone quality-based implant system: a preliminary report of stage I & stage II. Implant Dent 7(1):35–42

    Google Scholar 

  131. Kido H, Schulz EE, Kumar A, Lozada J, Saha S (1997) Implant diameter and bone density: effect on initial stability and pull-out resistance. J Oral Implantol 23(4):163–169

    Google Scholar 

  132. Stach RM, Kohles SS (2003) A meta-analysis examining the clinical survivability of machined-surfaced and osseotite implants in poor-quality bone. Implant Dent 12(1):87–96

    Google Scholar 

  133. Higuchi KW, Folmer T, Kultje C (1995) Implant survival rates in partially edentulous patients: a 3-year prospective multicenter study. J Oral Maxillofac Surg 53(3):264–268

    Google Scholar 

  134. von Wowern N, Harder F, Hjorting-Hansen E, Gotfredsen K (1990) ITI implants with overdentures: a prevention of bone loss in edentulous mandibles? Int J Oral Maxillofac Implants 5(2):135–139

    Google Scholar 

  135. Newton JP, Yemm R, Abel RW, Menhinick S (1993) Changes in human jaw muscles with age and dental state. Gerodontology 10(1):16–22

    Google Scholar 

  136. Bakke M, Moller E (1992) Craniomandibular disorders and masticatory muscle function. Scand J Dent Res 100(1):32–38

    Google Scholar 

  137. Klemetti E (1996) A review of residual ridge resorption and bone density. J Prosthet Dent 75(5):512–514

    Google Scholar 

  138. Klemetti E, Vainio P, Kroger H (1994) Muscle strength and mineral densities in the mandible. Gerodontology 11(2):76–79

    Google Scholar 

  139. Manson JD (1976) Bone morphology and bone loss in periodontal disease. J Clin Periodontol 3(1):14–22

    Google Scholar 

  140. Newton JP, McManus FC, Menhenick S (2004) Jaw muscles in older overdenture patients. Gerodontology 21(1):37–42

    Google Scholar 

  141. Paganini-Hill A (1995) The benefits of estrogen replacement therapy on oral health. The Leisure World cohort. Arch Intern Med 155(21):2325–2329

    Google Scholar 

  142. Klemetti E, Heikela E (1995) Craniomandibular disorders, edentulousness and the clinically estimated size of the masseter muscle. Cranio 13(3):173–176

    Google Scholar 

  143. Krall EA (2001) The periodontal-systemic connection: implications for treatment of patients with osteoporosis and periodontal disease. Ann Periodontol 6(1):209–213

    Google Scholar 

  144. Saag KG, Emkey R, Schnitzer TJ, Brown JP, Hawkins F, Goemaere S, Thamsborg G, Liberman UA, Delmas PD, Malice MP, Czachur M, Daifotis AG (1998) Alendronate for the prevention and treatment of glucocorticoid-induced osteoporosis. Glucocorticoid-Induced Osteoporosis Intervention Study Group. N Engl J Med 339(5):292–299

    Google Scholar 

  145. Dawson-Hughes B, Dallal GE, Krall EA, Sadowski L, Sahyoun N, Tannenbaum S (1990) A controlled trial of the effect of calcium supplementation on bone density in postmenopausal women. N Engl J Med 323(13):878–883

    Google Scholar 

  146. Grodstein F, Colditz GA, Stampfer MJ (1996) Post-menopausal hormone use and tooth loss: a prospective study. J Am Dent Assoc 127(3):370–377, quiz

    Google Scholar 

  147. Wical KE, Swoope CC (1974) Studies of residual ridge resorption. II. The relationship of dietary calcium and phosphorus to residual ridge resorption. J Prosthet Dent 32(1):13–22

    Google Scholar 

  148. Wical KE, Brussee P (1979) Effects of a calcium and vitamin D supplement on alveolar ridge resorption in immediate denture patients. J Prosthet Dent 41(1):4–11

    Google Scholar 

  149. Grodstein F, Colditz GA, Stampfer MJ (1998) Tooth loss and hormone use in postmenopausal women. Compend Contin Educ Dent [Suppl] (22):S9–16

  150. Krall EA, Garcia RI, Dawson-Hughes B (1996) Increased risk of tooth loss is related to bone loss at the whole body, hip, and spine. Calcif Tissue Int 59(6):433–477

    Google Scholar 

  151. Krall EA, Dawson-Hughes B, Hannan MT, Wilson PW, Kiel DP (1997) Postmenopausal estrogen replacement and tooth retention. Am J Med 102(6):536–542

    Google Scholar 

  152. Reinhardt RA, Payne JB, Maze CA, Patil KD, Gallagher SJ, Mattson JS (1999) Influence of estrogen and osteopenia/osteoporosis on clinical periodontitis in postmenopausal women. J Periodontol 70(8):823–828

    Google Scholar 

  153. Allen IE, Monroe M, Connelly J, Cintron R, Ross SD (2000) Effect of postmenopausal hormone replacement therapy on dental outcomes: systematic review of the literature and pharmacoeconomic analysis. Manag Care Interface 13(4):93–99

    Google Scholar 

  154. Faine MP (1995) Dietary factors related to preservation of oral and skeletal bone mass in women. J Prosthet Dent 73(1):65–72

    Google Scholar 

  155. Krall EA, Wehler C, Garcia RI, Harris SS, Dawson-Hughes B (2001) Calcium and vitamin D supplements reduce tooth loss in the elderly. Am J Med 111(6):452–456

    Google Scholar 

  156. Parfitt AM, Mundy GR, Roodman GD, Hughes DE, Boyce BF (1996) A new model for the regulation of bone resorption, with particular reference to the effects of bisphosphonates. J Bone Miner Res 11(2):150–159

    Google Scholar 

  157. Roberts WE, Simmons KE, Garetto LP, DeCastro RA (1992) Bone physiology and metabolism in dental implantology: risk factors for osteoporosis and other metabolic bone diseases. Implant Dent 1(1):11–21

    Google Scholar 

  158. von Wowern N (2001) General and oral aspects of osteoporosis: a review. Clin Oral Investig 5(2):71–82

    Google Scholar 

  159. Sambrook PN (2005) How to prevent steroid-induced osteoporosis. Ann Rheum Dis 64(2):176–178

    Google Scholar 

  160. Fujimoto T, Niimi A, Sawai T, Ueda M (1998) Effects of steroid-induced osteoporosis on osseointegration of titanium implants. Int J Oral Maxillofac Implants 13(2):183–189

    Google Scholar 

  161. Shirai H, Sato T, Oka M, Hara T, Mori S (2002) Effect of calcium supplementation on bone dynamics of the maxilla, mandible and proximal tibia in experimental osteoporosis. J Oral Rehabil 29(3):287–294

    Google Scholar 

  162. Yoshinari M, Oda Y, Inoue T, Matsuzaka K, Shimono M (2002) Bone response to calcium phosphate-coated and bisphosphonate-immobilized titanium implants. Biomaterials 23(14):2879–2885

    Google Scholar 

  163. Keller JC, Stewart M, Roehm M, Schneider GB (2004) Osteoporosis-like bone conditions affect osseointegration of implants. Int J Oral Maxillofac Implants 19(5):687–694

    Google Scholar 

  164. Jacobs R, Ghyselen J, Koninckx P, van Steenberghe D (1996) Long-term bone mass evaluation of mandible and lumbar spine in a group of women receiving hormone replacement therapy. Eur J Oral Sci 104(1):10–16

    Google Scholar 

  165. Kribbs PJ (1992) Two-year changes in mandibular bone mass in an osteoporotic population. J Prosthet Dent 67(5):653–655

    Google Scholar 

  166. Bollen AM, Taguchi A, Hujoel PP, Hollender LG (2001) Fractal dimension on dental radiographs. Dentomaxillofac Radiol 30(5):270–275

    Google Scholar 

  167. Nakamoto T, Taguchi A, Ohtsuka M, Suei Y, Fujita M, Tanimoto K, Tsuda M, Sanada M, Ohama K, Takahashi J, Rohlin M (2003) Dental panoramic radiograph as a tool to detect postmenopausal women with low bone mineral density: untrained general dental practitioners’ diagnostic performance. Osteoporos Int 14(8):659–664

    Google Scholar 

  168. Persson RE, Hollender LG, Powell LV, MacEntee MI, Wyatt CC, Kiyak HA, Persson GR (2002) Assessment of periodontal conditions and systemic disease in older subjects. I. Focus on osteoporosis. J Clin Periodontol 29(9):796–802

    Google Scholar 

  169. Taguchi A, Sanada M, Krall E, Nakamoto T, Ohtsuka M, Suei Y, Tanimoto K, Kodama I, Tsuda M, Ohama K (2003) Relationship between dental panoramic radiographic findings and biochemical markers of bone turnover. J Bone Miner Res 18(9):1689–1694

    Google Scholar 

  170. Tozum TF, Taguchi A (2004) Role of dental panoramic radiographs in assessment of future dental conditions in patients with osteoporosis and periodontitis. N Y State Dent J 70(1):32–35

    Google Scholar 

  171. von Wowern N (1977) Variations in structure within the trabecular bone of the mandible. Scand J Dent Res 85(7):613–622

    Google Scholar 

  172. Hausamen JE, Schliephake H (1990) [Oromaxillofacial surgical treatment in aging patients]. Z Gerontol 23(6):330–337

    Google Scholar 

  173. Sooriyamoorthy M, Gower DB (1989) Hormonal influences on gingival tissue: relationship to periodontal disease. J Clin Periodontol 16(4):201–218

    Google Scholar 

  174. Bothur S, Jonsson G, Sandahl L (2003) Modified technique using multiple zygomatic implants in reconstruction of the atrophic maxilla: a technical note. Int J Oral Maxillofac Implants 18(6):902–904

    Google Scholar 

  175. Boyes-Varley JG, Howes DG, Lownie JF (2003) The zygomaticus implant protocol in the treatment of the severely resorbed maxilla. SADJ 58(3):106–114

    Google Scholar 

  176. Astrand P, Nord PG, Branemark PI (1996) Titanium implants and onlay bone graft to the atrophic edentulous maxilla: a 3-year longitudinal study. Int J Oral Maxillofac Surg 25(1):25–29

    Google Scholar 

  177. Becktor JP, Isaksson S, Sennerby L (2004) Survival analysis of endosseous implants in grafted and nongrafted edentulous maxillae. Int J Oral Maxillofac Implants 19(1):107–115

    Google Scholar 

  178. Li KK, Stephens WL, Gliklich R (1996) Reconstruction of the severely atrophic edentulous maxilla using Le Fort I osteotomy with simultaneous bone graft and implant placement. J Oral Maxillofac Surg 54(5):542–546

    Google Scholar 

  179. McGrath CJ, Schepers SH, Blijdorp PA, Hoppenreijs TJ, Erbe M (1996) Simultaneous placement of endosteal implants and mandibular onlay grafting for treatment of the atrophic mandible. A preliminary report. Int J Oral Maxillofac Surg 25(3):184–188

    Google Scholar 

  180. Peleg M, Mazor Z, Chaushu G, Garg AK (1998) Sinus floor augmentation with simultaneous implant placement in the severely atrophic maxilla. J Periodontol 69(12):1397–1403

    Google Scholar 

  181. Smedberg JI, Johansson P, Ekenback D, Wannfors D (2001) Implants and sinus-inlay graft in a 1-stage procedure in severely atrophied maxillae: prosthodontic aspects in a 3-year follow-up study. Int J Oral Maxillofac Implants 16(5):668–674

    Google Scholar 

  182. Verhoeven JW, Ruijter J, Cune MS, Terlou M, Zoon M (2000) Onlay grafts in combination with endosseous implants in severe mandibular atrophy: one year results of a prospective, quantitative radiological study. Clin Oral Implants Res 11(6):583–594

    Google Scholar 

Download references

Acknowledgement

The authors wish to thank Dr. Joseph R. Dettori / Olympic Research, Seattle, WA, USA, for the independent literature search

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to B. Hohlweg-Majert.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hohlweg-Majert, B., Schmelzeisen, R., Pfeiffer, B.M. et al. Significance of osteoporosis in craniomaxillofacial surgery: A review of the literature. Osteoporos Int 17, 167–179 (2006). https://doi.org/10.1007/s00198-005-1967-4

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00198-005-1967-4

Keywords

Navigation