Abstract
The purpose of this study was to prospectively evaluate symptom change after discontinuation of extracorporeal magnetic stimulation (EMS) in women with overactive bladder (OAB). A total of 48 women with OAB were included. We applied 10 Hz of repetitive magnetic stimulation with a “magnetic chair” for 20 min, twice weekly for 8 weeks. Changes in OAB symptoms at 2, 12, and 24 weeks after discontinuing the EMS were evaluated. Twenty-seven (56.3%) patients were cured compared with the baseline at 2 weeks: the cure rate was determined as 68.8% (33/48 patients), 56.3% (27/48), and 50% (8/16) for urgency, frequency, and urge incontinence, respectively. The mean number of voids per 24 h was decreased by 42.8% (from 14.5 ± 4.3, to 8.3 ± 1.5, P < 0.001) at 2 weeks after treatment. Maximum voided volume did not change significantly, but the mean voided volume increased significantly after stimulation. Twenty-six (96.3%) patients among the 27 patients who achieved a cure at 2 weeks, maintained improvement at 24 weeks; the therapeutic effect on urgency, frequency, and urge incontinence persisted in 26 (78.8%) of 33 patients, 26 (96.3%) of 27 patients, and six (75%) of eight patients, respectively. There were no significant changes in urodynamic parameters. Of the 14 patients with detrusor overactivity, the condition was no longer observed in four (28.6%) patients. EMS has a beneficial effect on women with OAB. Our data suggest EMS may have a significant carry-over effect in well-selected OAB patients.
Similar content being viewed by others
References
Abrams P, Cardozo L, Fall M, Griffiths D, Rosier P, Ulmsten U, van Kerrebroeck P, Victor A, Wein A (2002) The standardisation of terminology of lower urinary tract function: report from the Standardisation sub-committee of the International continence society. Neurourol Urodyn 21:167–178
Stewart WF, Van Rooyen JB, Cundiff GW, Abrams P, Herzog AR, Corey R, Hunt TL, Wein AJ (2003) Prevalence and burden of overactive bladder in the United States. World J Urol 20:327–336
Milsom I, Abrams P, Cardozo L, Roberts RG, Thuroff J, Wein AJ (2001) How widespread are the symptoms of an overactive bladder and how are they managed? A population-based prevalence study. BJU Int 87:760–766
(2000) Overactive bladder and its treatments consensus conference. London, UK, July 4, 1999. Urology 55:1–84
Chapple CR, Yamanishi T, Chess-Williams R (2002) Muscarinic receptor subtypes and management of the overactive bladder. Urology 60:82–88; Discussion 88–89
Groen J, Bosch JL (2001) Neuromodulation techniques in the treatment of the overactive bladder. BJU Int 87:723–731
Brubaker L (2000) Electrical stimulation in overactive bladder. Urology 55:17–23; Discussion 31–12
Appell RA (1998) Electrical stimulation for the treatment of urinary incontinence. Urology 51:24–26
Smith JJ 3rd (1996) Intravaginal stimulation randomized trial. J Urol 155:127–130
Quek P (2005) A critical review on magnetic stimulation: what is its role in the management of pelvic floor disorders? Curr Opin Urol 15:231–235
Sheriff MK, Shah PJ, Fowler C, Mundy AR, Craggs MD (1996) Neuromodulation of detrusor hyper-reflexia by functional magnetic stimulation of the sacral roots. Br J Urol 78:39–46
McFarlane JP, Foley SJ, de Winter P, Shah PJ, Craggs MD (1997) Acute suppression of idiopathic detrusor instability with magnetic stimulation of the sacral nerve roots. Br J Urol 80:734–741
Nixon A, Colman S, Sabounjian L, Sandage B, Schwiderski UE, Staskin DR, Zinner N (2005) A validated patient reported measure of urinary urgency severity in overactive bladder for use in clinical trials. J Urol 174:604–607
Schafer W, Abrams P, Liao L, Mattiasson A, Pesce F, Spangberg A, Sterling AM, Zinner NR, van Kerrebroeck P (2002) Good urodynamic practices: uroflowmetry, filling cystometry, and pressure-flow studies. Neurourol Urodyn 21:261–274
Fujishiro T, Enomoto H, Ugawa Y, Takahashi S, Ueno S, Kitamura T (2000) Magnetic stimulation of the sacral roots for the treatment of stress incontinence: an investigational study and placebo controlled trial. J Urol 164:1277–1279
Yamanishi T, Yasuda K, Suda S, Ishikawa N, Sakakibara R, Hattori T (2000) Effect of functional continuous magnetic stimulation for urinary incontinence. J Urol 163:456–459
Galloway NT, El-Galley RE, Sand PK, Appell RA, Russell HW, Carlin SJ (2000) Update on extracorporeal magnetic innervation (EXMI) therapy for stress urinary incontinence. Urology 56:82–86
Shaker H, Wang Y, Loung D, Balbaa L, Fehlings MG, Hassouna MM (2000) Role of C-afferent fibres in the mechanism of action of sacral nerve root neuromodulation in chronic spinal cord injury. BJU Int 85:905–910
Unsal A, Saglam R, Cimentepe E (2003) Extracorporeal magnetic stimulation for the treatment of stress and urge incontinence in women—results of 1-year follow-up. Scand J Urol Nephrol 37:424–428
Yokoyama T, Fujita O, Nishiguchi J, Nozaki K, Nose H, Inoue M, Ozawa H, Kumon H (2004) Extracorporeal magnetic innervation treatment for urinary incontinence. Int J Urol 11:602–606
Bradshaw HD, Barker AT, Radley SC, Chapple CR (2003) The acute effect of magnetic stimulation of the pelvic floor on involuntary detrusor activity during natural filling and overactive bladder symptoms. BJU Int 91:810–813
Galloway NT, El-Galley RE, Sand PK, Appell RA, Russell HW, Carlan SJ (1999) Extracorporeal magnetic innervation therapy for stress urinary incontinence. Urology 53:1108–1111
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Choe, J.H., Choo, MS. & Lee, KS. Symptom change in women with overactive bladder after extracorporeal magnetic stimulation: a prospective trial. Int Urogynecol J 18, 875–880 (2007). https://doi.org/10.1007/s00192-006-0261-0
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00192-006-0261-0