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Tissue engineering a clinically useful extracellular matrix biomaterial

  • 2005 IUGA GRAFTS ROUNDTABLE
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Abstract

Implantable biomaterials are one of the most useful tools in the surgeon’s armamentarium, yet there is much room for improvement. Chronic pain, tissue erosion, and late infections are just a few of the serious complications that can occur with conventional, inert materials. In contrast, tissue-inductive materials exist today. Combinations of biologically important molecules for directing cell growth and providing structural stability can be found in naturally occuring extracellular matrices. These “soft-tissue skeletons” of Mother Nature can be harvested, processed, and provided in a medically safe and biologically active form for repairing many different tissues in the human body. The future of surgical practice may well be determined by how well these new implant materials recreate the tissues they replace.

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Authors and Affiliations

  1. Adjunct Assistant Professor of Veterinary Clinical Sciences, School of Veterinary Medicine, Purdue University, West Lafayette, IN, USA

    Michael Hiles

  2. Cook Biotech Incorporated, 1425 Innovation Place, West Lafayette, IN, 47906, USA

    Michael Hiles

  3. Department of Veterinary Pathobiology, School of Veterinary Medicine, Purdue University, West Lafayette, IN, USA

    Jason Hodde

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  1. Michael Hiles
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  2. Jason Hodde
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Correspondence to Michael Hiles.

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Hiles, M., Hodde, J. Tissue engineering a clinically useful extracellular matrix biomaterial. Int Urogynecol J 17 (Suppl 1), 39–43 (2006). https://doi.org/10.1007/s00192-006-0104-z

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  • DOI: https://doi.org/10.1007/s00192-006-0104-z

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