References
McKindley D, Fabian TC, Boucher BA, Croce MA, Proctor KG. (1995) Antibiotic pharmacokinetics following fluid resuscitation from traumatic shock. Arch Surg 130:1321–1329
Mimoz O, Jacolot A, Padoin C, Quillard J, Tod M, Louchahi K, Samii K, Petitjean O (1996) Influence of experimental rat model of multiple organ dysfunction on cefepime and amikacin pharmacokinetics. Antimicrob Agents Chemother 40:819–821
Van Dalen R, Vree TB (1990) Pharmacokinetics of antibiotics in critically ill patients. Intensive Care Med 16(suppl 3):S235–S238
Jacolot A, Incagnoli, Edouard AR, Tod M, Petitjean O, Samii K, Mimoz O (1999) Pharmacokinetics of cefpirome during the posttraumatic systemic inflammatory response syndrome. Intensive Care Med 25:486–491
Lipman J (2001) Low cefpirome levels during twice daily dosing in critically ill septic patients: pharmacokinetic modeling calls for more frequent dosing. Intensive Care Med 27: DOI:10.1007/s001340000741
Craig WA (1993) The pharmacokinetics of cefpirome - rationale for a twelvehour dosing regimen. Scand J Infect Dis (suppl) 91:33–40
Paradis D, Vallee F, Allard S, Bisson C, Daviau N, Drapeau N, Auger F, LeBel M (1992) Comparative study of pharmacokinetics and serum bactericidal activities of cefpirome, ceftazidime, ceftriaxone, imipenem and ciprofloxacin. Antimicrob Agents Chemother 36:2085–2092
Moise P, Schentag J (1998) Pharmacokinetic and pharmacodynamic modelling of antibiotic therapy. Curr Opin Infect Dis 11:673–680
Craig WA (1998) Pharmacokinetic/ pharmacodynamic parameters: rationale for antibacterial dosing of mice and men. Clin Infect Dis 26:1–12
Firsov AA, Vostrov SN, Shevchenko A, Portnoy YA, Zinner S (1998) A new approach to in vitro comparisons of antibiotics in dynamic models: equivalent area under the curve/MIC breakpoints and equi-efficient doses of trovafloxacin and ciprofloxacin against bacteria of similar susceptibilities. Antimicrob Agents Chemother 42:2841–2847
Corvaisier S, Maire PH, Bouvier d'Yvoire MY, Barbaut X, Bleyzac N, Jelliffe RW (1998) Comparisons between antimicrobial pharmacodynamic indices and bacterial killing as described by using the Zhi model. Antimicrob Agents Chemother 42:1731–1737
Thomas JK, Forrest A, Bhavnani M, Hyatt JM, Cheng A, Ballow CH, Schentag JJ (1998) Pharmacodynamic evaluation of factors associated with the development of bacterial resistance in acutely ill patients during therapy. Antimicrob Agents Chemother 42:521–527
Carmeli Y, Troillet N, Eliopoulos GM, Samore MH (1999) Emergence of antibiotic-resistant Pseudomonas aeruginosa: comparison of risks associated with different antipseudomonal agents. Antimicrob Agents Chemother 43:1379–1382
Manduru M, Mihm LB, White RL, Friedrich LV, Flume PA, Bosso JA (1997) Comparative bactericidal activity of ceftazidime against isolates of Pseudomonas aeruginosa as assessed in an in vitro pharmacodynamic model versus the traditional time-kill method. Antimicrob Agents Chemother 41:2527–2532
Yourassowsky E, Van der Linden MP, Lismont MJ, Crokaert F (1981) Early response of Pseudomonas aeruginosa growth curve to cefsulodin and n-formimidoyl thienamycin. In : Current chemotherapy and immunotherapy. Proceedings of the 12th International Congress of Chemotherapy, 1:514-516 (American Society for Microbiology, Washington, DC)
Matzke GR, Frye RF, Joy MS, Palevsky PM (2000) Determinants of ceftazidime clearance by continuous venovenous hemofiltration and continuous venovenous hemodialysis. Antimicrob Agents Chemother 44:1639–1644
Turnidge JD (1998) The pharmacodynamics of P-lactams. Clin Infect Dis 27:10–22
Cappelletty DM (1999) Evaluation of several dosing regimens of cefepime, with various simulations of renal function, against clinical isolates of Pseudomonas aeruginosa in a pharmacodynamic infection model. Antimicrob Agents Chemother 43:129–133
Eng (1984) Examination of Gram-negative bacilli from meningitis patients who failed or relapsed on moxalactam therapy. Antimicrob Agents Chemother 26:850–856
Potel G, Chan NP, Pangon B, Fantin B, Vallois J-M, Faurisson F, Carbon C, (1991). Single daily dosing of antibiotics: importance of in vitro killing rate, serum half-life and protein binding. Antimicrob Agents Chemother 35:2085–2090
Vincent JL, (1997) Dear Sirs, I’m sorry to say that I don’t like you. Crit Care Med 25:372–374
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Crokaert, F. Pharmacodynamics, a tool for a better use of antibiotics?. Intensive Care Med 27, 340–343 (2001). https://doi.org/10.1007/s001340100865
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DOI: https://doi.org/10.1007/s001340100865