Skip to main content
Log in

“Salvage treatment” for infections by extensively- and pan-drug-resistant pathogens is common and often sub-optimal

  • Letter
  • Published:
Intensive Care Medicine Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

References

  1. Bassetti M, De Waele JJ, Eggimann P, Garnacho-Montero J, Kahlmeter G, Menichetti F et al (2015) Preventive and therapeutic strategies in critically ill patients with highly resistant bacteria. Intensive Care Med 41:776–795

    Article  CAS  PubMed  Google Scholar 

  2. Wertheim H, Van Nguyen K, Hara GL, Gelband H, Laxminarayan R, Mouton J et al (2013) Global survey of polymyxin use: a call for international guidelines. J Glob Antimicrob Resist 1:131–134

    Article  PubMed  PubMed Central  Google Scholar 

  3. Garonzik SM, Li J, Thamlikitkul V, Paterson DL, Shoham S, Jacob J, Silveira FP et al (2011) Population pharmacokinetics of colistin methanesulfonate and formed colistin in critically ill patients from a multicenter study provide dosing suggestions for various categories of patients. Antimicrob Agents Chemother 55:3284–3294

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Polymyxin Article-31 referral—annex II. http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/referrals/Polymyxin-containing_medicines/human_referral_000383.jsp&mid=WC0b01ac05805c516f. Assessed Jan 2017

  5. Nation RL, Garonzik SM, Li J, Thamlikitkul V, Giamarellos-Bourboulis EJ, Paterson DL et al (2016) Updated United States and European dose recommendations for intravenous colistin: how do they perform? Clin Infect Dis 62:552–558

    Article  PubMed  Google Scholar 

Download references

Acknowledgements

The study was designed and performed by the Study Group “Infections in Critically Ill Patients” (ESGCIP), of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID). Investigators are listed in S7 Table, Electronic supplement. A preliminary analysis of the results was presented as a Poster (No 4204) in the 24th ECCMID 2014, 10–13 May 2014, Barcelona, Spain.

Author information

Authors and Affiliations

Authors

Consortia

Corresponding author

Correspondence to Garyfallia Poulakou.

Ethics declarations

Funding

This study has not received any funding.

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors.

Conflicts of interest

On behalf of all authors, the corresponding author states that there is no conflict of interest.

Additional information

The ESGCIP Investigators are given in acknowledgements.

Electronic supplementary material

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Poulakou, G., Matthaiou, D.K., Bassetti, M. et al. “Salvage treatment” for infections by extensively- and pan-drug-resistant pathogens is common and often sub-optimal. Intensive Care Med 43, 1164–1166 (2017). https://doi.org/10.1007/s00134-017-4796-y

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00134-017-4796-y

Keywords

Navigation