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Experiences with continuous intra-arterial blood gas monitoring: precision and drift of a pure optode-system

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Abstract

Objective

The utility of continuous intra-arterial blood gas analysis (CBGA) with combined electrochemical and optode sensors has been demonstrated. More recently, a pure optode sensor with a changed sensing element architecture has become available. The aim was to determine the measurement accuracy and long-term stability of the new sensor.

Design

A prospective explorative study was performed. Simultaneous measurements of intermittent blood gas analyses (IBGA) (ABL 610, Radiometer, Copenhagen) and CBGA (Diametrics Medical, High Wycombe, Bucks., UK) were compared using Bland-Altman analysis.

Patients

Twenty-five patients admitted to the ICU and requiring mechanical ventilation for an expected minimum of about 96 h were included.

Results

Mean monitoring time was 106.1 (range 15–231) hours. Bias and precision for PO2 were −0.2 kPa (1%)±1.8 kPa (9.5%); PCO2: 0.03 kPa (0.6%)±0.44 kPa (9.3%); pH: −0.001 (0.01%)±0.04 (0.45%). The sensor showed no change of measurement characteristics during 4 days of measurement. However, in 69 cases continuous monitoring was interrupted (reversible sudden drops of PO2 measurement) possibly caused by thrombotic deposition and/or sensor bending and accidental sensor retraction.

Conclusions

The precision and bias of the PCO2- and pH-sensing elements were in line with the findings of the older sensor technology. The possibility that the PO2 optode could offer greater accuracy than the older technology is suggested by comparisons with results reported in previous studies. No sensor drift occurred during long-term measurement over more than 4 days.

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Acknowledgments

This study was supported by a cooperation contract between Philips Medical Systems (Böblingen, Germany) and the Department of Anesthesiology and Critical Care Medicine of the University of Halle-Wittenberg, Germany.

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Authors and Affiliations

  1. Dept. of Anesthesiology and Intensive Care Medicine, Martin-Luther-University, Magdeburger Strasse 16, 06097, Halle, Germany

    Matthias Menzel, Jens Soukup, Dirk Henze, Kai Engelbrecht, Maik Senderreck, Alexander Scharf, Andreas Rieger & Stefan Grond

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  1. Matthias Menzel
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  2. Jens Soukup
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  7. Andreas Rieger
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  8. Stefan Grond
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Correspondence to Matthias Menzel.

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Menzel, M., Soukup, J., Henze, D. et al. Experiences with continuous intra-arterial blood gas monitoring: precision and drift of a pure optode-system. Intensive Care Med 29, 2180–2186 (2003). https://doi.org/10.1007/s00134-003-1962-1

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  • DOI: https://doi.org/10.1007/s00134-003-1962-1

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